Oleanolic acid and ursolic acid: Research perspectives

Journal of Ethnopharmacology - Tập 100 Số 1-2 - Trang 92-94 - 2005
Jie Liu1
1Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis, NCI at NIEHS, 111 Alexander Drive, Research Triangle Park, NC 27709, USA.

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Tài liệu tham khảo

Chen, 2005, Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect, Journal of Pharmacy and Pharmacology, 57, 259, 10.1211/0022357055407

Dinkova-Kostova, 2005, Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress., 4584

Farina, 1998, Synthesis and anti-ulcer activity of new derivatives of glycyrrhetic, oleanolic and ursolic acids, Pharmacology, 53, 22

Kim, 2004, Inhibition of cytochrome P450 activities by oleanolic acid and ursolic acid in human liver microsomes, Life Sciences, 74, 2769, 10.1016/j.lfs.2003.10.020

Konopleva, 2004, The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1 9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia, Cancer Research, 64, 7927, 10.1158/0008-5472.CAN-03-2402

Liu, 1995, Pharmacology of oleanolic acid and ursolic acid, Journal of Ethnopharmacology, 49, 57, 10.1016/0378-8741(95)90032-2

Liu, 1999, Gene expression pattern in mice and rats produced by the hepatoprotectant oleanolic acid, Hepatology, 30, 948

Liu, 1998, Protection against carbon tetrachloride hepatotoxicity by oleanolic acid is not mediated through metallothionein, Toxicology Letters, 95, 77, 10.1016/S0378-4274(98)00009-5

Mix, 2001, A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines, Arthritis Rheumatology, 44, 1096, 10.1002/1529-0131(200105)44:5<1096::AID-ANR190>3.0.CO;2-6

Murakami, 2004, Ursolic acid, an antagonist for transforming growth factor (TGF)-beta1, FEBS Letters, 566, 55, 10.1016/j.febslet.2004.04.036

Oguro, 1998, Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin, Toxicological Sciences, 45, 88

Ovesna, 2004, Pentacyclic triterpenoic acids: new chemoprotective compounds, Minireview Neoplasma, 51, 327

Somova, 2003, Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension, Phytomedicine, 10, 115, 10.1078/094471103321659807

Suh, 1998, Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages, Cancer Research, 58, 717

Zou, 2004, c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1 9-dien-28-oate in human lung cancer cells, Cancer Research, 64, 7570, 10.1158/0008-5472.CAN-04-1238