Oleanolic acid, a natural triterpenoid improves blood glucose tolerance in normal mice and ameliorates visceral obesity in mice fed a high-fat diet

Després, 2007, Cardiovascular disease under the influence of excess visceral fat, Crit. Path Cardiol., 6, 51, 10.1097/HPC.0b013e318057d4c9

Ibrahim, 2009, Subcutaneous and visceral adipose tissue: structural and functional differences, Obes. Rev.

Pagotto, 2008, Pharmacological therapy of obesity, G. Ital. Cardiol. (Rome), 9, 83S

Braakman, 2009, Rimonabant induces partial seizures in a patient with a history of generalized epilepsy, Epilepsia, 50, 2171, 10.1111/j.1528-1167.2009.02203.x

Lee, 2009, New trends in medicinal chemistry approaches to antiobesity therapy, Curr. Top. Med. Chem., 9, 564, 10.2174/156802609788897853

Lee, 2009, The current status and future perspectives of studies of cannabinoid receptor 1 antagonists as anti-obesity agents, Curr. Top. Med. Chem., 9, 482, 10.2174/156802609788897844

Cefalu, 2008, Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans, Endocr. Metab. Immune Disord. Drug Targets, 8, 78, 10.2174/187153008784534376

Hasani-Ranjbar, 2009, A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity, World J. Gastroenterol., 15, 3073, 10.3748/wjg.15.3073

Jäger, 2009, Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts, Molecules, 14, 2016, 10.3390/molecules14062016

Yoshizumi, 2006, Lupane-type saponins from leaves of Acanthopanax sessiliforus and their inhibitory activity on pancreatic lipase, J. Agric. Food Chem., 54, 335, 10.1021/jf052047f

Ali, 2006, Alpha-amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus, J. Ethnopharmacol., 107, 449, 10.1016/j.jep.2006.04.004

Chung, 2006, Inhibition of diacylglycerol acyltransferase by betulinic acid from Alnus hirsuta, Planta Med., 72, 267, 10.1055/s-2005-916178

Atta-ur-Rahman, 2008, Alpha-glucosidase inhibitory activity of triterpenoids from Cichorium intybus, J. Nat. Prod., 71, 910, 10.1021/np800001v

de Melo, 2009, Betulinic acid, a natural pentacyclic triterpenoid, prevents abdominal fat accumulation in mice fed a high-fat diet, J. Agric. Food Chem., 57, 8776, 10.1021/jf900768w

Amico, 2009, Bioassay-guided isolation of antiproliferative compounds from grape (Vitis vinifera) stems, Nat. Prod. Commun., 4, 27

Liu, 1995, Pharmacology of oleanolic acid and ursolic acid, J. Ethnopharmacol., 49, 57, 10.1016/0378-8741(95)90032-2

Hou, 2009, Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors, Phytother. Res., 23, 614, 10.1002/ptr.2661

Gao, 2009, Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan-induced diabetic rats, Phytother Res, 23, 1257, 10.1002/ptr.2603

Zhang, 2008, Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities, Bioorg. Med. Chem., 16, 8697, 10.1016/j.bmc.2008.07.080

Yunoki, 2008, Effect of dietary wine pomace extract and oleanolic acid on plasma lipids in rats fed high-fat diet and its DNA microarray analysis, J. Agric. Food Chem., 56, 12052, 10.1021/jf8026217

Rodriguez-Rodriguez, 2009, Effects of pomace olive oil-enriched diets on endothelial function of small mesenteric arteries from spontaneously hypertensive rats, Br. J. Nutr., 29, 1

Blum, 2009, 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds, Mol. Cell. Endocrinol., 301, 132, 10.1016/j.mce.2008.08.028

Velloso, 2008, Diet-induced inflammation of the hypothalamus in obesity, Neuroimmunomodulation, 15, 189, 10.1159/000153423

Popovic, 2005, Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity, Nutr. Neurosci., 8, 1, 10.1080/10284150400027107

Mahato, 1994, 13C NMR spectra of pentacyclic triterpenoids—a compilation and some salient features, Phytochemistry, 37, 1517, 10.1016/S0031-9422(00)89569-2

Ma, 2005, The cytotoxic activity of ursolic acid derivatives, Eur. J. Med. Chem., 40, 582, 10.1016/j.ejmech.2005.01.001

Debora, 2004, Effect of palatable hyperlipidic diet on lipid metabolism of sedentary and exercised rats, Nutrition, 20, 218, 10.1016/j.nut.2003.10.008

Klok, 2007, The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review, Obes. Rev., 8, 21, 10.1111/j.1467-789X.2006.00270.x

Cordido, 2009, Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect, Curr. Drug Discov. Technol., 6, 34, 10.2174/157016309787581048

Weigle, 2003, Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet, J. Clin. Endocrinol. Metab., 88, 1577, 10.1210/jc.2002-021262

Tschöp, 2001, Circulating ghrelin levels are decreased in human obesity, Diabetes, 50, 707, 10.2337/diabetes.50.4.707

Handjieva-Darlenska, 2009, The effect of high-fat diet on plasma ghrelin and leptin levels in rats, J. Physiol. Biochem., 65, 157, 10.1007/BF03179066

Teodoro, 2008, Oleanolic acid enhances insulin secretion in pancreatic beta-cells, FEBS Lett., 582, 1375, 10.1016/j.febslet.2008.03.026

Eder, 2009, The major inflammatory mediator interleukin-6 and obesity, Inflamm. Res., 58, 727, 10.1007/s00011-009-0060-4

Marquez-Martin, 2006, Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells, Cytokine, 36, 211, 10.1016/j.cyto.2006.12.007

Katz, 2007, Punica granatum: heuristic treatment for diabetes mellitus, J. Med. Food, 10, 213, 10.1089/jmf.2006.290