Older donors and kidney transplantation

Transplant International - Tập 6 Số 1 - Trang 39-41 - 1993
Creagh, T. A.1,2,3,4, McLean, P. A.2,3,4, Donovan, M. G.2,3,4, Walshe, J. J.3,4, Murphy, D. M.2,3,4
1Department of Surgery, Beaumont Hospital, Dublin 9, Ireland
2Department of Urology, Beaumont Hospital, Dublin 9, Ireland
3Department of Transplantation, Beaumont Hospital, Dublin 9, Ireland
4The Royal College of Surgeons in Ireland, Dublin, Ireland

Tóm tắt

Reluctance to use kidneys from older donors (>50 years of age) is based on reports of inferior results. We reviewed our experience with 45 kidneys transplanted from older donors. Primary nonfunction, immediate graft function, and 1-, 2- and 3-year graft survival rates were similar to those obtained with kidneys transplanted from donors aged between 20 and 40 years. Renal function at 1 year (as measured by serum creatinine) was poorer in kidneys from older donors. No beneficial effect with respect to graft survival was noted with cyclosporin therapy compared to conventional immunosuppression; however, the numbers are small. We conclude that kidneys from older donors are a valuable source for transplantation.

Tài liệu tham khảo

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