Obstructive Sleep Apnea and Risk of Cardiovascular Events and All-Cause Mortality: A Decade-Long Historical Cohort Study

PLoS Medicine - Tập 11 Số 2 - Trang e1001599
Tetyana Kendzerska1, Andrea S. Gershon2,3,4,1, Gillian Hawker2,5,4,1, Richard Leung2,6,7, George Tomlinson2,8,1
1Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
2Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
3Department of Medicine Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
4Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
5Department of Medicine, Women's College Hospital, Toronto, Ontario, Canada
6Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada
7Sleep Laboratory, St. Michael's Hospital, Toronto, Ontario, Canada
8Department of Medicine, University Health Network/Mt Sinai Hospital, Toronto, Ontario, Canada

Tóm tắt

Từ khóa


Tài liệu tham khảo

PE Peppard, 2013, Increased prevalence of sleep-disordered breathing in adults, Am J Epidemiol

LJ Epstein, 2009, Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults, J Clin Sleep Med, 5, 263, 10.5664/jcsm.27497

RS Leung, 2012, Mechanisms of sleep-disordered breathing: causes and consequences, Pflugers Arch, 463, 213, 10.1007/s00424-011-1055-x

TD Bradley, 2009, Obstructive sleep apnoea and its cardiovascular consequences, Lancet, 373, 82, 10.1016/S0140-6736(08)61622-0

M Kohler, 2010, Mechanisms of vascular damage in obstructive sleep apnea, Nat Rev Cardiol, 7, 677, 10.1038/nrcardio.2010.145

HA Chami, 2013, Vascular inflammation and sleep disordered breathing in a community-based cohort, Sleep, 36, 763, 10.5665/sleep.2644

T Kendzerska, 2014, Untreated obstructive sleep apnea and the risk for serious long-term adverse outcomes: a systematic review, Sleep Med Rev, 18, 49, 10.1016/j.smrv.2013.01.003

Polysomnography in patients with obstructive sleep apnea: an evidence-based analysis, Ont Health Technol Assess Ser, 6, 1

BA Edwards, 2013, PSGs: more than just the AHI, J Clin Sleep Med, 9, 527, 10.5664/jcsm.2738

DJ Eckert, 2013, Defining phenotypic causes of obstructive sleep apnea: Identification of novel therapeutic targets, Am J Respir Crit Care Med, 188, 996, 10.1164/rccm.201303-0448OC

NM Punjabi, 2009, Sleep-disordered breathing and mortality: a prospective cohort study, PLoS Med, 6, e1000132, 10.1371/journal.pmed.1000132

T Young, 2008, Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort, Sleep, 31, 1071

DJ Gottlieb, 2010, Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study, Circulation, 122, 352, 10.1161/CIRCULATIONAHA.109.901801

S Redline, 2010, Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study, Am J Respir Crit Care Med, 182, 269, 10.1164/rccm.200911-1746OC

(2005) Improving health care data in Ontario. ICES investigative report Toronto: Institute for Clinical Evaluative Sciences.

Policies and procedures manual for the assistive devices program, Ministry of Health and Long-Term Care, 1

Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force, Sleep, 22, 667, 10.1093/sleep/22.5.667

J Fleetham, 2006, Canadian Thoracic Society guidelines: diagnosis and treatment of sleep disordered breathing in adults, Can Respir J, 13, 387, 10.1155/2006/627096

Harrell FE (2001) Regression modeling strategies: with applications to linear models, logistic regression, and survival analysis. New York: Springer. xxii, 568 .

P Grambsch, 1994, Proportional hazards tests and diagnostics based on weighted residuals, Biometrika, 81, 515, 10.1093/biomet/81.3.515

MJ Azur, 2011, Multiple imputation by chained equations: what is it and how does it work?, Int J Methods Psychiatr Res, 20, 40, 10.1002/mpr.329

S Van Buuren, 2011, MICE: multivariate imputation by chained equations in R, Journal of Statistical Software, 45, 1

Rubin DB (1987) Multiple imputation for nonresponse in surveys. New York: Wiley. xxix, 258 p.

AC Atkinson, 1980, A note on the generalized information criterion for choice of a model, Biometrika, 67, 413, 10.1093/biomet/67.2.413

YC Chia, 2011, Review of tools of cardiovascular disease risk stratification: interpretation, customisation and application in clinical practice, Singapore Med J, 52, 116

Harrell FE (2013) RMS: regression modeling strategies, R package verson 4.0-0. <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://CRANR-projectorg" xlink:type="simple">http://CRANR-projectorg</ext-link>[mgn]package = rms.

JM Marin, 2005, Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study, Lancet, 365, 1046, 10.1016/S0140-6736(05)74229-X

NJ Buchner, 2007, Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk, Am J Respir Crit Care Med, 176, 1274, 10.1164/rccm.200611-1588OC

NM Punjabi, 2008, Sleep-disordered breathing and cardiovascular disease: an outcome-based definition of hypopneas, Am J Respir Crit Care Med, 177, 1150, 10.1164/rccm.200712-1884OC

J Jun, 2010, Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice, Atherosclerosis, 209, 381, 10.1016/j.atherosclerosis.2009.10.017

GE Foster, 2010, Intermittent hypoxia increases arterial blood pressure in humans through a Renin-Angiotensin system-dependent mechanism, Hypertension, 56, 369, 10.1161/HYPERTENSIONAHA.110.152108

A Atkeson, 2008, Mechanisms of endothelial dysfunction in obstructive sleep apnea, Vasc Health Risk Manag, 4, 1327, 10.2147/VHRM.S4078

BB Koo, 2011, Association of incident cardiovascular disease with periodic limb movements during sleep in older men: outcomes of sleep disorders in older men (MrOS) study, Circulation, 124, 1223, 10.1161/CIRCULATIONAHA.111.038968

AS Walters, 2010, Evidence continues to mount on the relationship of restless legs syndrome/periodic limb movements in sleep to hypertension, cardiovascular disease, and stroke, Sleep, 33, 287, 10.1093/sleep/33.3.287

AN Vgontzas, 2010, Insomnia with short sleep duration and mortality: the Penn State cohort, Sleep, 33, 1159, 10.1093/sleep/33.9.1159

B Krakow, 2012, Prospective assessment of nocturnal awakenings in a case series of treatment-seeking chronic insomnia patients: a pilot study of subjective and objective causes, Sleep, 35, 1685

Kendzerska T, Shapiro C. (2013) Associations and consequences of hypersomnias: morbidity and mortality. Kushida CA, editor. The encyclopedia of sleep. Waltham (Massachusetts): Academic Press <volume>2</volume>: : 460–468.

DJ Gottlieb, 2013, Sleep apnea cardiovascular clinical trials – current status and steps forward: The International Collaboration of Sleep Apnea Cardiovascular Trialists, Sleep, 36, 975, 10.5665/sleep.2790

F Barbe, 2012, Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial, JAMA, 307, 2161, 10.1001/jama.2012.4366

T Young, 2003, Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study, Am J Respir Crit Care Med, 167, 1181, 10.1164/rccm.200209-1055OC

V Pialoux, 2009, Effect of cardiorespiratory fitness on vascular regulation and oxidative stress in postmenopausal women, Hypertension, 54, 1014, 10.1161/HYPERTENSIONAHA.109.138917

JA Eastham, 2002, Nomograms as predictive models, Semin Urol Oncol, 20, 108, 10.1053/suro.2002.32936

A Iasonos, 2008, How to build and interpret a nomogram for cancer prognosis, J Clin Oncol, 26, 1364, 10.1200/JCO.2007.12.9791

DY Lin, 1998, Assessing the sensitivity of regression results to unmeasured confounders in observational studies, Biometrics, 54, 948, 10.2307/2533848

DJ Hand, 2006, Classifier technology and the illusion of progress, Stat Sci, 21, 1, 10.1214/088342306000000060

I Tzoulaki, 2009, Assessment of claims of improved prediction beyond the Framingham risk score, JAMA, 302, 2345, 10.1001/jama.2009.1757

MJ Pencina, 2010, Statistical methods for assessment of added usefulness of new biomarkers, Clin Chem Lab Med, 48, 1703, 10.1515/CCLM.2010.340