Observation of cavitation pits on mechanical heart valve surfaces in an artificial heart used in in vitro testing

Journal of Artificial Organs - Tập 13 - Trang 17-23 - 2010
Hwansung Lee1, Akihiko Homma1, Eisuke Tatsumi1, Yoshiyuki Taenaka1
1Department of Artificial Organs, Research Institute, National Cardiovascular Center, Osaka, Japan

Tóm tắt

Our group has developed an electrohydraulic total artificial heart (EHTAH) with two diaphragm-type blood pumps. Cavitation in a mechanical heart valve (MHV) causes valve surface damage. The objective of this study was to investigate the possibility of estimating the MHV cavitation intensity using the slope of the driving pressure just before valve closure in this artificial heart. Twenty-five and twenty-three-millimeter Medtronic Hall valves were mounted at the inlet and outlet ports, respectively, of both pumps. The EHTAH was connected to the experimental endurance tester developed by our group, and tested under physiological pressure conditions. Cavitation pits could be seen on the inlet valve surface and on the outlet valve surface of the right and left blood pumps. The pits on the inlet valves were more severe than those on the outlet valves in both blood pumps, and the cavitation pits on the inlet valve of the left blood pump were more severe than those on the inlet valve of the right blood pump. The longer the pump running time, the more severe the cavitation pits on the valve surfaces. Cavitation pits were concentrated near the contact area with the valve stop. The major cause of these pits was the squeeze flow between the leaflet and valve stop.

Tài liệu tham khảo

Lee HS, Taenaka Y, Kitamura S. Mechanism for cavitation in the mechanical heart valve with an artificial heart: nuclei and viscosity dependence. Artif Organs. 2005;29:41–6. Knapp RT, Daily JW, Hammitt FG. Cavitation. Iowa City: Institute of Hydraulic Research, University of Iowa; 1979. Brennen CE. Cavitation and bubble dynamics. New York: Oxford University Press; 1995. Klepetko W, Moritz A, Mlczoch J, Schurawitzki H, Domanig E, Wolner E. Leaflet fracture in Edward–Duromedics bileaflet valves. J Thorac Cardiovasc Surg. 1989;97:90–4. Ericsson A, Lindblom D, Semb G, Huysmans HA, Thulin LI, Scully HE, et al. Strut fracture with Björk–Shily 70° convexo-concave valve: an international multi-institutional follow-up study. Eur J Cardiothorac Surg. 1992;6:339–46. Bottio T, Casarotto D, Thiene G, Caprili L, Angelini A, Gerosa G. Leaflet escape in a new bileaflet mechanical valve: TRI technologies. Circulation. 2003;107:2303–6. Dexter EU, Aluri S, Radcliffe RR, Zhn H, Carlson DD, Heilman TE, et al. In vivo demonstration of cavitation potential of a mechanical heart valve. ASAIO J. 1999;45:436–41. Nakata M, Masuzawa T, Tatsumi E, Taenaka Y, Nishimura T, Tsukiya T, et al. Characterization and optimization of the flow pattern inside a diaphragm blood pump based on flow visualization techniques. ASAIO J. 1998;44:M714–8. Lee HS, Homma A, Tatsumi E, Taenaka Y. Observation of cavitation pits on a mechanical heart valve surface in an artificial heart: in vivo testing. J Artif Organs. 2009;12:105–10. Potthast K, Erdönmen G, Schnelke C, Sellin L, Sliwka U, Schöndube F, et al. Origin and appearance of HITS induced by prosthetic heart valves: an in vitro study. Int J Artif Organs. 2000;23:441–5. Biancucci BA, Deutsch S, Geselowitz DB, Tarbell JM. In vitro studies of gas bubble formation by mechanical heart valves. J Heart Valve Dis. 1999;8:186–96. Zapanta CM, Stinebring DR, Sneckenberger DS, Deutsch S, Geselowitz DB, Tarbell JM, et al. In vivo observation of cavitation on prosthetic heart valves. ASAIO J. 1996;42:M550–5. Sneckenberger DS, Stinebring DR, Deutsch S, Geselowitz DB, Tarbell JM. Mitral heart valve cavitation in an artificial heart environment. J Heart Valve Dis. 1996;5:216–27. Makhijani VB, Yang HQ, Singhal AK, Hwang NHC. An experimental-computational analysis of MHV cavitation: effect of leaflet squeezing and rebound. J Heart Valve Dis. 1994;3(Suppl I):S35–48. Lee HS, Tatsumi E, Taenaka Y. Effects of the driving condition of a pneumatic ventricular assist device on the cavitation intensity of the inlet and outlet mechanical heart valves. ASAIO J. 2009;55:328–34. Graf T, Reul H, Dietz W, Wilmes R, Rau G. Cavitation of mechanical heart valve under physiologic conditions. J Heart Valve Dis. 1992;1:131–41. Lin HY, Bianccucci BA, Deutsch S, Fontaine AA, Tarbell JM. Observation and quantification of gas bubble formation on a mechanical heart valve. Trans ASME. 2000;122:304–9. Lee HS, Taenaka y. Observation and quantification of cavitation on a mechanical heart valve with an electro-hydraulic total artificial heart. Int J Artif Organs. 2006;29:303–7.