Obesity-induced dysregulation of skin-resident PPARγ+ Treg cells promotes IL-17A-mediated psoriatic inflammation

Immunity - Tập 56 - Trang 1844-1861.e6 - 2023
Pulavendran Sivasami1, Cody Elkins1, Pamela P. Diaz-Saldana1, Kyndal Goss2,3, Amy Peng1, Michael Hamersky4, Jennifer Bae1, Miaoer Xu1, Brian P. Pollack5,6,7, Edwin M. Horwitz2,3, Christopher D. Scharer1, Lindsey Seldin4,5,6,7, Chaoran Li1,6,7
1Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
2Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA
3Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA,
4Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322 USA
5Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA
6Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA
7Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA

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