Nutrition, frailty, and sarcopenia

Alfonso J. Cruz-Jentoft1, Eva Kiesswetter2, Michael Drey2, Cornel Sieber2
1Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
2Institute for Biomedicine of Aging, University of Erlangen-Nürnberg, Nuremberg, Germany

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Petit-Dutaillis D, Chavany J, Guiot G (1953) Operative frailty of patients with chromophobe adenoma of abnormal symptomatology; prognostic value of homonymous lateral hemianopsia. Presse Med 61:341–343

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K (2013) Frailty in elderly people. Lancet 381:752–762. doi: 10.1016/S0140-6736(12)62167-9

Fried LP, Tangen CM, Walston J et al. (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146–M156. doi: 10.1093/gerona/56.3.M146

Rockwood K, Song X, MacKnight C et al (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ 173:489–495. doi: 10.1503/cmaj.050051

Rosenberg IH (2011) Sarcopenia: origins and clinical relevance. Clin Geriatr Med 27:337–339. doi: 10.1016/j.cger.2011.03.003

Goodpaster BH, Park SW, Harris TB et al (2006) The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci 61:1059–1064

Fielding RA, Vellas B, Evans WJ et al (2011) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 12:249–256. doi: 10.1016/j.jamda.2011.01.003

Morley JE, Abbatecola AM, Argiles JM et al (2011) Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc 12:403–409. doi: 10.1016/j.jamda.2011.04.014

Cruz-Jentoft AJ, Baeyens JP, Bauer JM et al (2010) Sarcopenia: European consensus on definition and diagnosis: report of the european working group on sarcopenia in older people. Age Ageing 39:412–423. doi: 10.1093/ageing/afq034

Cruz-Jentoft AJ, Landi F (2014) Sarcopenia. Clin Med (Lond) 14:183–186. doi: 10.7861/clinmedicine.14-2-183

Morley JE, Vellas B, Abellan van Kan G et al (2013) Frailty consensus: a call to action. J Am Med Dir Assoc 14:392–397. doi: 10.1016/j.jamda.2013.03.022

Studenski SA, Peters KW, Alley DE et al (2014) The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci 69:547–558. doi: 10.1093/gerona/glu010

Morley JE, von Haehling S, Anker SD, Vellas B (2014) From sarcopenia to frailty: a road less traveled. J Cachexia Sarcopenia Muscle 5:5–8. doi: 10.1007/s13539-014-0132-3

Cruz-jentoft AJ, Michel JP (2013) Sarcopenia: a useful paradigm for physical frailty. Eur Geriatr Med 4:102–105. doi: 10.1016/j.eurger.2013.02.009

Samper-Ternent R, Reyes-Ortiz C, Ottenbacher KJ, Cano CA (2016) Frailty and sarcopenia in Bogotá: results from the SABE Bogotá study. Aging Clin Exp Res. doi: 10.1007/s40520-016-0561-2 (ahead of print)

Walston J, Hadley E, Ferrucci L et al (2006) Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc 54:991–1001. doi: 10.1111/j.1532-5415.2006.00745.x

Walston JD (2012) Sarcopenia in older adults. Curr Opin Rheumatol 24:623–627. doi: 10.1097/BOR.0b013e328358d59b

Ahmed N, Mandel R, Fain MJ (2007) Frailty: an emerging geriatric syndrome. Am J Med 120:748–753. doi: 10.1016/j.amjmed.2006.10.018

Bauer JM, Sieber CC (2008) Sarcopenia and frailty: a clinician’s controversial point of view. Exp Gerontol 43:674–678. doi: 10.1016/j.exger.2008.03.007

Cruz-Jentoft AJ, Landi F, Topinková E, Michel J (2010) Understanding sarcopenia as a geriatric syndrome. Curr Opin Clin Nutr Metab Care 13:1–7. doi: 10.1097/MCO.0b013e328333c1c1

Hubbard RE, Lang IA, Llewellyn DJ, Rockwood K (2010) Frailty, body mass index, and abdominal obesity in older people. J Gerontol A Biol Sci Med Sci 65:377–381. doi: 10.1093/gerona/glp186

Bollwein J, Volkert D, Diekmann R et al (2013) Nutritional status according to the mini nutritional assessment (MNA(R)) and frailty in community dwelling older persons: a close relationship. J Nutr Health Aging 17:351–356. doi: 10.1007/s12603-013-0009-8

Shikany JM, Barrett-Connor E, Ensrud KE et al (2014) Macronutrients, diet quality, and frailty in older men. J Gerontol A Biol Sci Med Sci 69:695–701. doi: 10.1093/gerona/glt196

Barillaro C, Liperoti R, Martone AM, Onder G, Landi F (2013) The new metabolic treatments for sarcopenia. Aging Clin Exp Res 25:119–127. doi: 10.1007/s40520-013-0030-0

Newman AB, Lee JS, Visser M et al (2005) Weight change and the conservation of lean mass in old age: the health, aging and body composition study. Am J Clin Nutr 82:872–878 (quiz 915)

Morley JE (2013) Pathophysiology of the anorexia of aging. Curr Opin Clin Nutr Metab Care 16:27–32. doi: 10.1097/MCO.0b013e328359efd7

Landi F, Laviano A, Cruz-Jentoft AJ (2010) The anorexia of aging: is it a geriatric syndrome? J Am Med Dir Assoc 11:153–156. doi: 10.1016/j.jamda.2009.09.003

Serra-Prat M, Mans E, Palomera E, Clavé P (2013) Gastrointestinal peptides, gastrointestinal motility, and anorexia of aging in frail elderly persons. Neurogastroenterol Motil 25:291–e245. doi: 10.1111/nmo.12055

Bartali B, Frongillo EA, Bandinelli S et al (2006) Low nutrient intake is an essential component of frailty in older persons. J Gerontol A Biol Sci Med Sci 61:589–593

Smit E, Winters-Stone KM, Loprinzi PD, Tang AM, Crespo CJ (2013) Lower nutritional status and higher food insufficiency in frail older US adults. Br J Nutr 110:172–178. doi: 10.1017/S000711451200459X

Kim JE, Lee YH, Huh JH, Kang DR, Rhee Y, Lim SK (2014) Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: the fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008–2009. Osteoporos Int 25:2189–2198. doi: 10.1007/s00198-014-2745-y

Volpi E, Campbell WW, Dwyer JT et al (2013) Is the optimal level of protein intake for older adults greater than the recommended dietary allowance. J Gerontol A Biol Sci Med Sci 68:677–681. doi: 10.1093/gerona/gls229

Tieland M, Borgonjen-Van Den Berg K, van Loon LJ, de Groot LC (2012) Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement. Eur J Nutr 51:173–179. doi: 10.1007/s00394-011-0203-6

Bauer J, Biolo G, Cederholm T et al (2013) Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group. J Am Med Dir Assoc 14:542–559. doi: 10.1016/j.jamda.2013.05.021

Deutz NE, Bauer JM, Barazzoni R et al (2014) Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group. Clin Nutr 33:929–936. doi: 10.1016/j.clnu.2014.04.007

Houston DK, Ding J, Nicklas BJ et al (2009) Overweight and obesity over the adult life course and incident mobility limitation in older adults: the health, aging and body composition study. Am J Epidemiol 169:927–936. doi: 10.1093/aje/kwp007

Meng X, Zhu K, Devine A, Kerr DA, Binns CW, Prince RL (2009) A 5-year cohort study of the effects of high protein intake on lean mass and BMC in elderly postmenopausal women. J Bone Miner Res 24:1827–1834. doi: 10.1359/jbmr.090513

Beasley JM, LaCroix AZ, Neuhouser ML et al (2010) Protein intake and incident frailty in the women’s health initiative observational study. J Am Geriatr Soc 58:1063–1071. doi: 10.1111/j.1532-5415.2010.02866.x

Bollwein J, Diekmann R, Kaiser MJ et al (2013) Distribution but not amount of protein intake is associated with frailty: a cross-sectional investigation in the region of Nürnberg. Nutr J 12:109. doi: 10.1186/1475-2891-12-109

Valenzuela RE, Ponce JA, Morales-Figueroa GG, Muro KA, Carreón VR, Alemán-Mateo H (2013) Insufficient amounts and inadequate distribution of dietary protein intake in apparently healthy older adults in a developing country: implications for dietary strategies to prevent sarcopenia. Clin Interv Aging 8:1143–1148. doi: 10.2147/CIA.S49810

Wyss M, Kaddurah-Daouk R (2000) Creatine and creatinine metabolism. Physiol Rev 80:1107–1213

Harris RC, Söderlund K, Hultman E (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci (Lond) 83:367–374. doi: 10.1042/cs0830367

Gualano B, Roschel H, Lancha-Jr AH, Brightbill CE, Rawson ES (2012) In sickness and in health: the widespread application of creatine supplementation. Amino Acids 43:519–529. doi: 10.1007/s00726-011-1132-7

Kley RA, Tarnopolsky MA, Vorgerd M (2011) Creatine for treating muscle disorders. Cochrane Database Syst Rev. doi: 10.1002/14651858.CD004760.pub3

Santos RV, Bassit RA, Caperuto EC, Costa Rosa LF (2004) The effect of creatine supplementation upon inflammatory and muscle soreness markers after a 30 km race. Life Sci 75:1917–1924. doi: 10.1016/j.lfs.2003.11.036

Palus S, von Haehling S, Springer J (2014) Muscle wasting: an overview of recent developments in basic research. J Cachexia Sarcopenia Muscle 5:193–198. doi: 10.1007/s13539-014-0157-7

Rieu I, Balage M, Sornet C et al (2007) Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats. Nutrition 23:323–331. doi: 10.1016/j.nut.2006.12.013

Leenders M, van Loon LJ (2011) Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes. Nutr Rev 69:675–689. doi: 10.1111/j.1753-4887.2011.00443.x

Szcześniak KA, Ostaszewski P, Fuller JC, Ciecierska A, Sadkowski T (2015) Dietary supplementation of β-hydroxy-β-methylbutyrate in animals—a review. J Anim Physiol Anim Nutr (Berl) 99:405–417. doi: 10.1111/jpn.12234

Fitschen PJ, Wilson GJ, Wilson JM, Wilund KR (2013) Efficacy of β-hydroxy-β-methylbutyrate supplementation in elderly and clinical populations. Nutrition 29:29–36. doi: 10.1016/j.nut.2012.05.005

Wilson JM, Fitschen PJ, Campbell B et al (2013) International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB). J Int Soc Sports Nutr 10:6. doi: 10.1186/1550-2783-10-6

Dupuy C, Lauwers-Cances V, Van Kan GA et al (2013) Dietary vitamin D intake and muscle mass in older women. Results from a cross-sectional analysis of the EPIDOS study. J Nutr Health Aging 17:119–124. doi: 10.1007/s12603-012-0089-x

Kim JS, Wilson JM, Lee SR (2010) Dietary implications on mechanisms of sarcopenia: roles of protein, amino acids and antioxidants. J Nutr Biochem 21:1–13. doi: 10.1016/j.jnutbio.2009.06.014

Kim J, Lee Y, Kye S, Chung YS, Kim KM (2015) Association of vegetables and fruits consumption with sarcopenia in older adults: the Fourth Korea National Health and Nutrition Examination Survey. Age Ageing 44:96–102. doi: 10.1093/ageing/afu028

Mulero J, Zafrilla P, Martinez-Cacha A (2011) Oxidative stress, frailty and cognitive decline. J Nutr Health Aging 15:756–760

Hutchins-Wiese HL, Kleppinger A, Annis K et al (2013) The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women. J Nutr Health Aging 17:76–80. doi: 10.1007/s12603-012-0415-3

Gill TM, Gahbauer EA, Allore HG, Han L (2006) Transitions between frailty states among community-living older persons. Arch Intern Med 166:418–423. doi: 10.1001/archinte.166.4.418

Cruz-Jentoft AJ, Landi F, Schneider SM et al (2014) Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing 43:748–759. doi: 10.1093/ageing/afu115

Talegawkar SA, Bandinelli S, Bandeen-Roche K et al (2012) A higher adherence to a Mediterranean-style diet is inversely associated with the development of frailty in community-dwelling elderly men and women. J Nutr 142:2161–2166. doi: 10.3945/jn.112.165498

Kobayashi S, Asakura K, Suga H, Sasaki S, Three-generation SOWODAHSG (2013) High protein intake is associated with low prevalence of frailty among old Japanese women: a multicenter cross-sectional study. Nutr J 12:164.doi: 10.1186/1475-2891-12-164

Kim CO, Lee KR (2013) Preventive effect of protein-energy supplementation on the functional decline of frail older adults with low socioeconomic status: a community-based randomized controlled study. J Gerontol A Biol Sci Med Sci 68:309–316. doi: 10.1093/gerona/gls167

Brown JC, Harhay MO, Harhay MN (2016) Physical activity, diet quality, and mortality among sarcopenic older adults. Aging Clin Exp Res. doi: 10.1007/s40520-016-0559-9 (ahead of print)

Cesari M, Demougeot L, Boccalon H, Guyonnet S, Vellas B, Andrieu S (2014) The multidomain intervention to preveNt disability in ElDers (MINDED) project: rationale and study design of a pilot study. Contemp Clin Trials 38:145–154. doi: 10.1016/j.cct.2014.04.006

Tikkanen P, Lonnroos E, Sipila S, Nykanen I, Sulkava R, Hartikainen S (2014) Effects of comprehensive geriatric assessment-based individually targeted interventions on mobility of pre-frail and frail community-dwelling older people. Geriatr Gerontol Int 15:80–88. doi: 10.1111/ggi.12231