Nuovi farmaci a bersaglio molecolare nei tumori neuroendocrini gastroenteropancreatici
Tóm tắt
Từ khóa
Tài liệu tham khảo
Ito T, Lee L, Jensen RT (2016) Treatment of symptomatic neuroendocrine tumor syndromes: recent advances and controversies. Expert Opin Pharmacother 17(16):2191–2205
Öberg K, Lamberts SW (2016) Somatostatin analogues in acromegaly and gastroenteropancreatic neuroendocrine tumours: past, present and future. Endocr Relat Cancer 23(12):R551–566
Lee MS, O’Neil BH (2016) Summary of emerging personalized medicine in neuroendocrine tumors: are we on track? J Gastrointest Oncol 7(5):804–818
Broder MS, Beenhouwer D, Strosberg JR et al. (2015) Gastrointestinal neuroendocrine tumors treated with high dose octreotide-LAR: a systematic literature review. World J Gastroenterol 21(6):1945
Veenstra MJ, van Koetsveld PM, Dogan F et al (2016) Epidrug-induced upregulation of functional somatostatin type 2 receptors in human pancreatic neuroendocrine tumor cells. Oncotarget. Available from http://www.oncotarget.com/abstract/9462
Alonso-Gordoa T, Capdevila J, Grande E (2015) GEP-NETs update: biotherapy for neuroendocrine tumours. Eur J Endocrinol 172(1):R31–46
Pópulo H, Lopes JM, Soares P (2012) The mTOR signalling pathway in human cancer. Int J Mol Sci 13(2):1886–1918
Fazio N (2015) Neuroendocrine tumors resistant to mammalian target of rapamycin inhibitors: a difficult conversion from biology to the clinic. World J Clin Oncol 6(6):194–197
Manfredi GI, Dicitore A, Gaudenzi G et al. (2015) PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy. Endocrine 48(2):363–370
Hobday TJ, Qin R, Reidy-Lagunes D et al. (2015) Multicenter phase II trial of temsirolimus and bevacizumab in pancreatic neuroendocrine tumors. J Clin Oncol 33(14):1551–1556
Raymond E, Hobday T, Castellano D et al. (2011) Therapy innovations: tyrosine kinase inhibitors for the treatment of pancreatic neuroendocrine tumors. Cancer Metastasis Rev 30(S1):19–26