Nucleotide-binding oligomerization domain 1 acts in concert with the cholecystokinin receptor agonist, cerulein, to induce IL-33-dependent chronic pancreatitis

Frossard, 2008, Acute pancreatitis, Lancet, 371, 143, 10.1016/S0140-6736(08)60107-5 Braganza, 2011, Chronic pancreatitis, Lancet, 377, 1184, 10.1016/S0140-6736(10)61852-1 Steer, 1995, Chronic pancreatitis, N. Engl. J. Med., 332, 1482, 10.1056/NEJM199506013322206 Sah, 2011, Molecular mechanisms of pancreatic injury, Curr. Opin. Gastroenterol., 27, 444, 10.1097/MOG.0b013e328349e346 Saluja, 2007, Why does pancreatic overstimulation cause pancreatitis?, Annu. Rev. Physiol., 69, 249, 10.1146/annurev.physiol.69.031905.161253 Whitcomb, 2010, Genetic aspects of pancreatitis, Annu. Rev. Med., 61, 413, 10.1146/annurev.med.041608.121416 Etemad, 2001, Chronic pancreatitis: diagnosis, classification, and new genetic developments, Gastroenterology, 120, 682, 10.1053/gast.2001.22586 Dawra, 2011, Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis, Gastroenterology, 141, 2210, 10.1053/j.gastro.2011.08.033 Sah, 2013, Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice, Gastroenterology, 144, 1076, 10.1053/j.gastro.2013.01.041 Yamaguchi, 1989, Activation of proteases in cerulein-induced pancreatitis, Pancreas, 4, 565, 10.1097/00006676-198910000-00007 Ji, 2011, Digesting new information about the role of trypsin in pancreatitis, Gastroenterology, 141, 1972, 10.1053/j.gastro.2011.10.021 Akira, 2004, Toll-like receptor signalling, Nat. Rev. Immunol., 4, 499, 10.1038/nri1391 Strober, 2006, Signalling pathways and molecular interactions of NOD1 and NOD2, Nat. Rev. Immunol., 6, 9, 10.1038/nri1747 Kono, 2008, How dying cells alert the immune system to danger, Nat. Rev. Immunol., 8, 279, 10.1038/nri2215 Tsuji, 2012, Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis, Immunity, 37, 326, 10.1016/j.immuni.2012.05.024 Mithofer, 1996, Antibiotic treatment improves survival in experimental acute necrotizing pancreatitis, Gastroenterology, 110, 232, 10.1053/gast.1996.v110.pm8536862 Hoque, 2012, Sterile inflammatory response in acute pancreatitis, Pancreas, 41, 353, 10.1097/MPA.0b013e3182321500 Hoque, 2011, TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis, Gastroenterology, 141, 358, 10.1053/j.gastro.2011.03.041 Ulmasov, 2013, Differences in the degree of cerulein-induced chronic pancreatitis in C57BL/6 mouse substrains lead to new insights in identification of potential risk factors in the development of chronic pancreatitis, Am. J. Pathol., 183, 692, 10.1016/j.ajpath.2013.05.020 Masamune, 2013, Pancreatic stellate cells—multi-functional cells in the pancreas, Pancreatology, 13, 102, 10.1016/j.pan.2012.12.058 Watanabe, 2010, NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway, J. Clin. Invest., 120, 1645, 10.1172/JCI39481 Fichtner-Feigl, 2008, Cytokines mediating the induction of chronic colitis and colitis-associated fibrosis, Mucosal Immunol., 1 Suppl 1, S24, 10.1038/mi.2008.41 McHedlidze, 2013, Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis, Immunity, 39, 357, 10.1016/j.immuni.2013.07.018 Kempuraj, 2013, The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice, PLoS ONE, 8, e56866, 10.1371/journal.pone.0056866 Cayrol, 2014, IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy, Curr. Opin. Immunol., 31C, 31, 10.1016/j.coi.2014.09.004 Masamune, 2010, Nuclear expression of interleukin-33 in pancreatic stellate cells, Am. J. Physiol. Gastrointest. Liver Physiol., 299, G821, 10.1152/ajpgi.00178.2010 Li, 2014, IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice, J. Allergy Clin. Immunol., 134, 1422, 10.1016/j.jaci.2014.05.011 Seidelin, 2011, A role for interleukin-33 in T(H)2-polarized intestinal inflammation?, Mucosal Immunol., 4, 496, 10.1038/mi.2011.22 Monticelli, 2011, Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus, Nat. Immunol., 12, 1045, 10.1038/ni.2131 Li, 2014, Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation, J. Clin. Invest., 124, 3241, 10.1172/JCI73742 Lee, 2009, Type I interferon modulates monocyte recruitment and maturation in chronic inflammation, Am. J. Pathol., 175, 2023, 10.2353/ajpath.2009.090328 He, 2009, Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha, Cell, 137, 1100, 10.1016/j.cell.2009.05.021 Mancuso, 2007, Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria, J. Immunol., 178, 3126, 10.4049/jimmunol.178.5.3126 Ganal, 2012, Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota, Immunity, 37, 171, 10.1016/j.immuni.2012.05.020 Bonilla, 2012, The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses, Science, 335, 984, 10.1126/science.1215418 Ouziel, 2012, The ST2 pathway is involved in acute pancreatitis: a translational study in humans and mice, Am. J. Pathol., 180, 2330, 10.1016/j.ajpath.2012.03.009 Sesti-Costa, 2013, The IL-33/ST2 pathway controls coxsackievirus B5-induced experimental pancreatitis, J. Immunol., 191, 283, 10.4049/jimmunol.1202806 Schmieder, 2012, Interleukin-33 acts as a pro-inflammatory cytokine and modulates its receptor gene expression in highly metastatic human pancreatic carcinoma cells, Cytokine, 60, 514, 10.1016/j.cyto.2012.06.286 Ochi, 2012, MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells, J. Exp. Med., 209, 1671, 10.1084/jem.20111706 Liu, 2015, Collaborative interactions between type 2 innate lymphoid cells and antigen-specific CD4+ Th2 cells exacerbate murine allergic airway diseases with prominent eosinophilia, J. Immunol., 194, 3583, 10.4049/jimmunol.1400951 Zhang, 2014, Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin, Mol. Cell Biol., 34, 400, 10.1128/MCB.01070-13 Hagiwara, 2014, Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells, PLoS ONE, 9, e84072, 10.1371/journal.pone.0084072 Conway, 2014, Mosquito saliva serine protease enhances dissemination of dengue virus into the mammalian host, J. Virol., 88, 164, 10.1128/JVI.02235-13 Simons, 2015, A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression, J. Pathol., 235, 478, 10.1002/path.4472 Rommer, 2013, EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells, PLoS ONE, 8, e56308, 10.1371/journal.pone.0056308 van Westerloo, 2005, Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice, Am. J. Pathol., 166, 721, 10.1016/S0002-9440(10)62293-6 Gout, 2013, Isolation and culture of mouse primary pancreatic acinar cells, J. Vis. Exp., 78, e50514 Arai, 2015, Plasmacytoid dendritic cell activation and IFN-alpha production are prominent features of murine autoimmune pancreatitis and human igg4-related autoimmune pancreatitis, J. Immunol., 195, 3033, 10.4049/jimmunol.1500971