Nuclear Accumulation of Mutated β-Catenin in Hepatocellular Carcinoma Is Associated with Increased Cell Proliferation
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Murray, 1997, Mortality by cause for eight regions of the world: global burden of disease study, Lancet, 349, 1269, 10.1016/S0140-6736(96)07493-4
Nagai, 1998, Oncogenes, tumor suppressors, and co-factors in hepatocellular carcinoma, 182
Nagai, 1997, Comprehensive allelotyping of human hepatocellular carcinoma, Oncogene, 14, 2927, 10.1038/sj.onc.1201136
Murakami, 1991, Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas, Cancer Res, 51, 5520
Hsu, 1994, Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas, Cancer, 73, 42, 10.1002/1097-0142(19940101)73:1<42::AID-CNCR2820730109>3.0.CO;2-D
De Souza, 1995, M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity, Nat Genet, 11, 447, 10.1038/ng1295-447
Nishida, 1994, Amplification and overexpression of the cyclin D1 gene in aggressive hepatocellular carcinoma, Cancer Res, 54, 3107
de La Coste, 1998, Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas, Proc Natl Acad Sci USA, 95, 8847, 10.1073/pnas.95.15.8847
Miyoshi, 1998, Activation of the β-catenin gene in primary hepatocellular carcinoma by somatic alterations involving exon 3, Cancer Res, 58, 2524
He, 1998, Identification of c-myc as a target of the APC pathway, Science, 281, 1509, 10.1126/science.281.5382.1509
Tetsu, 1999, β-Catenin regulates expression of cyclin D1 in colon carcinoma cells, Nature, 398, 422, 10.1038/18884
Aberle, 1996, Cadherin-catenin complex: protein interactions and their implications for cadherin function, J Cell Biochem, 61, 514, 10.1002/(SICI)1097-4644(19960616)61:4<514::AID-JCB4>3.0.CO;2-R
Cadigan, 1997, Wnt signaling: a common theme in animal development, Genes Dev, 11, 3286, 10.1101/gad.11.24.3286
Polakis, 1997, The adenomatous polyposis coli (APC) tumor suppressor, Biochim Biophys Acta, 1332, F127
Clevers, 1997, TCF/LEF factors earn their wings, Trends Genet, 13, 485, 10.1016/S0168-9525(97)01305-X
Pennica, 1998, WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors, Proc Natl Acad Sci USA, 95, 14717, 10.1073/pnas.95.25.14717
Morin, 1997, Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC, Science, 275, 1787, 10.1126/science.275.5307.1787
Iwao, 1998, Activation of the β-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations, Cancer Res, 58, 1021
Polakis, 1999, The oncogenic activation of β-catenin, Curr Opin Genet Dev, 9, 15, 10.1016/S0959-437X(99)80003-3
Inomata, 1996, Alteration of β-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients, Cancer Res, 56, 2213
Palacios, 1998, Mutations in the β-catenin gene (CTNNB1) in endometrioid ovarian carcinomas, Cancer Res, 58, 1344
Fukuchi, 1998, Beta-catenin mutation in carcinoma of the uterine endometrium, Cancer Res, 58, 3526
Rimm, 1999, Frequent nuclear/cytoplasmic localization of β-catenin without exon 3 mutations in malignant melanoma, Am J Pathol, 154, 325, 10.1016/S0002-9440(10)65278-9
Pileri, 1997, Antigen retrieval techniques in immunohistochemistry: comparison of different methods, J Pathol, 183, 116, 10.1002/(SICI)1096-9896(199709)183:1<116::AID-PATH1087>3.0.CO;2-2
Barnes, 1995, Determination of cell proliferation, J Clin Pathol Clin Mol Pathol, 48, M2, 10.1136/mp.48.1.M2
Ishak, 1994
Ihara, 1996, Expression of epithelial cadherin and α- and β-catenins in nontumoral livers and hepatocellular carcinoma, Hepatology, 23, 1441
Voeller, 1998, Beta-catenin mutations in human prostate cancer, Cancer Res, 58, 2520
Rubinfeld, 1996, Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly, Science, 272, 1023, 10.1126/science.272.5264.1023
Ding, 1993, The putative tumor suppressor gene on chromosome 5q for hepatocellular carcinoma is distinct from the MCC and APC genes, Cancer Detect Prev, 17, 405
Tanaka, 1998, A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals, Proc Natl Acad Sci USA, 95, 10164, 10.1073/pnas.95.17.10164
Kitamoto, 1993, The assessment of proliferating cell nuclear antigen immunohistochemical staining in small hepatocellular carcinoma and its relationship to histologic characteristics and prognosis, Cancer, 72, 1859, 10.1002/1097-0142(19930915)72:6<1859::AID-CNCR2820720612>3.0.CO;2-A