Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner

Experimental Gerontology - Tập 119 - Trang 61-73 - 2019
Dong-Dong Huang1, Sheng-Dong Fan1, Xi-Yi Chen2, Xia-Lin Yan1, Xian-Zhong Zhang1, Bing-Wei Ma1, Ding-Ye Yu3, Wen-Yu Xiao4, Cheng-Le Zhuang1, Zhen Yu1,4
1Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China
2Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China
3Department of General Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
4Shanghai Tenth People's Hospital Chongming Branch Affiliated to Tongji University, Shanghai, China

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