Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease - Tập 1865 - Trang 1253-1264 - 2019
Tài liệu tham khảo
Swynghedauw, 1999
Dahlof, 2002, Cardiovascular morbidity and mortality in the Losartan Intervention For End point reduction in hypertension study (LIFE): a randomised trial against atenolol, Lancet, 359, 995, 10.1016/S0140-6736(02)08089-3
Swynghedauw, 2010, Molecular mechanisms in evolutionary cardiology failure, Ann. N. Y. Acad. Sci., 1188, 58, 10.1111/j.1749-6632.2009.05084.x
Diaz, 2018, Angiotensin II requires an intact cardiac thyrotropin-releasing hormone (TRH) system to induce cardiac hypertrophy in mouse, J. Mol. Cell. Cardiol., 24, 1, 10.1016/j.yjmcc.2018.09.009
P.C. Group, 2001, Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack, Lancet, 358, 1033, 10.1016/S0140-6736(01)06178-5
Fox, 2003, Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study), Lancet, 362, 782, 10.1016/S0140-6736(03)14286-9
Yusuf, 2000, Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators, N. Engl. J. Med., 342, 145, 10.1056/NEJM200001203420301
Sadoshima, 1993, Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro, Cell, 75, 977, 10.1016/0092-8674(93)90541-W
Sugden, 2001, Mechanotransduction in Cardiomyocyte Hypertrophy, Circulation, 103, 1375, 10.1161/01.CIR.103.10.1375
Yang, 2018, Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension, J. Hypertens., 36, 834, 10.1097/HJH.0000000000001613
Al, 2016, Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype, Proc. Natl. Acad. Sci. U. S. A., 113
Choi, 2016, Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion, J. Mol. Cell. Cardiol., 100, 64, 10.1016/j.yjmcc.2016.09.001
Takayanagi, 2015, Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II, Hypertension, 65, 1349, 10.1161/HYPERTENSIONAHA.115.05344
Lau, 2013, The predicted molecular weight of Nrf2: it is what it is not, Antioxid. Redox Signal., 18, 91, 10.1089/ars.2012.4754
Rojo de la Vega, 2018, NRF2 and the hallmarks of cancer, Cancer Cell., 34, 21, 10.1016/j.ccell.2018.03.022
Best, 2018, Synergy between the KEAP1/NRF2 and PI3K pathways drives non-small-cell lung cancer with an altered immune microenvironment, Cell Metab., 27, 935, 10.1016/j.cmet.2018.02.006
Chartoumpekis, 2018, Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice, JCI Insight, 3, 10.1172/jci.insight.97735
Kuda, 2018, Nrf2-mediated antioxidant defense and peroxiredoxin 6 are linked to biosynthesis of palmitic acid ester of 9-hydroxystearic acid, Diabetes, 67, 1190, 10.2337/db17-1087
Wang, 2014, Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins, J. Mol. Cell. Cardiol., 72, 305, 10.1016/j.yjmcc.2014.04.006
Li, 2011, Up-regulation of p27kip1 contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy, Carbohydr. Res., 90, 315
Qin, 2015, Nrf2-mediated cardiac maladaptive remodeling and dysfunction in a setting of autophagy insufficiency, Hypertension, 67, 107, 10.1161/HYPERTENSIONAHA.115.06062
Lee, 2003, Identification of the NF-E2-related Factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis, J. Biol. Chem., 278, 12029, 10.1074/jbc.M211558200
Nguyen, 2009, The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress, J. Biol. Chem., 284, 13291, 10.1074/jbc.R900010200
Li, 2009, Molecular mechanisms of Nrf2-mediated antioxidant response, Mol. Carcinog., 48, 91, 10.1002/mc.20465
Ma, 2013, Role of Nrf2 in oxidative stress and toxicity, Annu. Rev. Pharmacol. Toxicol., 53, 401, 10.1146/annurev-pharmtox-011112-140320
Kensler, 2006, Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway, Annu. Rev. Pharmacol. Toxicol., 47, 89, 10.1146/annurev.pharmtox.46.120604.141046
Li, 2009, Nrf2 protects against maladaptive cardiac responses to hemodynamic stress, Arterioscler. Thromb. Vasc. Biol., 29, 1843, 10.1161/ATVBAHA.109.189480
Barančík, 2016, Nrf2 as a key player of redox regulation in cardiovascular diseases, Physiol. Res., 65, S1, 10.33549/physiolres.933403
Erkens, 2015, Left ventricular diastolic dysfunction in Nrf2 knock out mice Is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function, Free Radic. Biol. Med., 89, 906, 10.1016/j.freeradbiomed.2015.10.409
Chen, 2017, Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy, Biochem. Biophys. Res. Commun., 494, 534, 10.1016/j.bbrc.2017.10.119
Fredj, 2005, Role of interleukin-6 in cardiomyocyte/cardiac fibroblast interactions during myocyte hypertrophy and fibroblast proliferation, J. Cell. Physiol., 204, 428, 10.1002/jcp.20307
Sano, 2000, Autocrine/Paracrine secretion of IL-6 family cytokines causes angiotensin II-induced delayed STAT3 activation, Biochem. Biophys. Res. Commun., 269, 798, 10.1006/bbrc.2000.2364
Mann, 2003, Stress-activated cytokines and the heart: from adaptation to maladaptation, Annu. Rev. Physiol., 65, 81, 10.1146/annurev.physiol.65.092101.142249
Yang, 2007, STAT3 regulates cytokine-mediated generation of inflammatory helper T cells, J. Biol. Chem., 282, 9358, 10.1074/jbc.C600321200
Loperena, 2018, Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: Roles of STAT3, interleukin 6 and hydrogen peroxide, Cardiovasc. Res., 114, 1547, 10.1093/cvr/cvy112
Wruck, 2011, Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter, J. Biol. Chem., 286, 4493, 10.1074/jbc.M110.162008
Minami, 2018, Prognostic significance of CD68, CD163 and folate receptor-β positive macrophages in hepatocellular carcinoma, Exp. Ther. Med., 15
Boytard, 2013, Role of proinflammatory CD68(+) mannose receptor(−) macrophages in peroxiredoxin-1 expression and in abdominal aortic aneurysms in humans, Arterioscler. Thromb. Vasc. Biol., 33, 431, 10.1161/ATVBAHA.112.300663
Chen, 2017, AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart, Biochem. Biophys. Res. Commun., 493, 1410, 10.1016/j.bbrc.2017.09.149
Ye, 2012, Translation of myocyte enhancer factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a calcineurin-dependent pathway, J. Mol. Cell. Cardiol., 53, 578, 10.1016/j.yjmcc.2012.07.013
Naya, 2002, Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor, Nat. Med., 8, 1303, 10.1038/nm789
Marfella, 2013, Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non-responders, Eur. J. Heart Fail., 15, 10.1093/eurjhf/hft088
Sardu, 2014, Functional role of miRNA in cardiac resynchronization therapy, Pharmacogenomics, 15, 10.2217/pgs.14.76
Sardu, 2016, Cardiac resynchronization therapy outcomes in type 2 diabetic patients: role of microRNA changes, J. Diabetes Res., 2016, 10.1155/2016/7292564
Sardu, 2018, Cardiovasc. Diabetol., 17, 137, 10.1186/s12933-018-0778-9
Sardu, 2018, Inflammatory cytokines and SIRT1 levels in subcutaneous abdominal fat: relationship with cardiac performance in overweight pre-diabetics patients, Front. Physiol., 9, 1030, 10.3389/fphys.2018.01030
Vicario, 2006, Effects of volume loading on strain rate and tissue Doppler velocity imaging in patients with idiopathic dilated cardiomyopathy, J. Cardiovasc. Med. (Hagerstown), 7, 852, 10.2459/01.JCM.0000253826.44234.09
Sardu, 2018, Stretch, injury and inflammation markers evaluation to predict clinical outcomes after implantable cardioverter defibrillator therapy in heart failure patients with metabolic syndrome, Front. Physiol., 9, 758, 10.3389/fphys.2018.00758
Ichikawa, 2009, Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes, PLoS One, 4, 10.1371/journal.pone.0008391
He, 2009, Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes, J. Mol. Cell. Cardiol., 46, 47, 10.1016/j.yjmcc.2008.10.007
Nako, 2012, Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF, Hypertens. Res., 35, 194, 10.1038/hr.2011.175
Soliman, 2017, Antihypertensive therapies and left ventricular hypertrophy, Curr. Hypertens. Rep., 19, 79, 10.1007/s11906-017-0777-3
Fagard, 2009, Regression of left ventricular mass by antihypertensive treatment: a meta-analysis of randomized comparative studies, Hypertension, 54, 1084, 10.1161/HYPERTENSIONAHA.109.136655
Dahlof, 1992, Reversal of cardiovascular structural changes when treating essential hypertension. The importance of the renin-angiotensin-aldosterone system, Am. J. Hypertens., 5, 900, 10.1093/ajh/5.12.900
Schmieder, 1996, Reversal of left ventricular hypertrophy in essential hypertension. A meta-analysis of randomized double-blind studies, JAMA, 275, 1507, 10.1001/jama.1996.03530430051039
Wang, 2016, Scutellarin protects cardiomyocyte ischemia–reperfusion injury by reducing apoptosis and oxidative stress, Life Sci., 157, 200, 10.1016/j.lfs.2016.01.018
Drenckhahn, 2015, Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart, Cardiovasc. Res., 106, 43, 10.1093/cvr/cvv028
Xu, 2006, Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice, J. Biol. Chem., 281, 9152, 10.1074/jbc.M510217200
Kweider, 2011, Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia, J. Biol. Chem., 286, 42863, 10.1074/jbc.M111.286880
Betz, 1998, Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects, J. Exp. Med., 188, 1955, 10.1084/jem.188.10.1955
Hilfiker-Kleiner, 2004, Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury, Circ. Res., 95, 187, 10.1161/01.RES.0000134921.50377.61
Hirota, 1999, Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress, Cell, 97, 189, 10.1016/S0092-8674(00)80729-1
