Nrf-2 transcriptionally activates P21 Cip/WAF1 and promotes A549 cell survival against oxidative stress induced by H 2 O 2

Chemico-Biological Interactions - Tập 285 - Trang 59-68 - 2018
Samarjit Jana1, Kartick Patra1, Jagannath Jana2, Deba Prasad Mandal1, Shamee Bhattacharjee1
1Department of Zoology, West Bengal State University, Berunanpukuria, Malikapur, North-24 Parganas, Barasat, Kolkata 700126, West Bengal, India
2Department of Biophysics, Bose Institute, Centenary Campus P 1/12, C. I. T. Road, Scheme – VII (M) Kolkata 700054, West Bengal, India

Tài liệu tham khảo

Trachootham, 2008, Redox regulation of cell survival, Antioxid. Redox. Sig., 10, 1343, 10.1089/ars.2007.1957 Martindale, 2002, Cellular response to oxidative stress: signaling for suicide and survival, J. Cell. Physiol., 192, 1, 10.1002/jcp.10119 Trachootham, 2008, Redox regulation of cell survival, Antioxid. Redox. Sig., 10, 1343, 10.1089/ars.2007.1957 Martindale, 2002, Cellular response to oxidative stress: signaling for suicide and survival, J. Cell. Physiol., 192, 1, 10.1002/jcp.10119 Ma, 2013, Role of nrf2 in oxidative stress and toxicity, Annu. Rev. Pharmacol. Toxicol., 53, 401, 10.1146/annurev-pharmtox-011112-140320 Jaiswal, 2004, Nrf2 signaling in coordinated activation of antioxidant gene expression, Free Radic. Biol. Med., 36, 1199, 10.1016/j.freeradbiomed.2004.02.074 Chen, 2009, Direct interaction between Nrf2 and p21 (Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response, Mol. Cell., 34, 663, 10.1016/j.molcel.2009.04.029 Esposito, 1998, F.Cimino. A new p21waf1/cip1 isoform is an early event of cell response to oxidative stress, Cell Death Differ., 5, 940, 10.1038/sj.cdd.4400427 Rotblat, 2012, NRF2 and p53: januses in cancer?, Oncotarget, 3, 1272, 10.18632/oncotarget.754 Faraonio, 2006, p53 suppresses the Nrf2-dependent transcription of antioxidant response genes, J. Biol. Chem., 281, 39776, 10.1074/jbc.M605707200 Hayes, 2009, NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer, Trends Biochem. Sci., 34, 176, 10.1016/j.tibs.2008.12.008 Seve, 2005, Chemoresistance in non-small cell lung cancer, Curr. Med. Chem. Anticancer. Agents, 5, 73, 10.2174/1568011053352604 Kweon, 2006, Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate, J. Biol. Chem., 281, 33761, 10.1074/jbc.M604748200 Broos, 2011, ConTra v2: a tool to identify transcription factor binding sites across species, update 2011, Nucleic Acids Res., 39, W74, 10.1093/nar/gkr355 Rössig, 2001, Akt-dependent phosphorylation of p21 (Cip1) regulates PCNA binding and proliferation of endothelial cells, Mol. Cell Biol., 21, 5644, 10.1128/MCB.21.16.5644-5657.2001 Wang, 2008, Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2, Carcinogenesis, 29, 1235, 10.1093/carcin/bgn095 Zhang, 2010, The Nrf2-Keap1-ARE signaling pathway: the regulation and dual function of Nrf2 in cancer, Antioxid. Redox. Sig., 13, 1623, 10.1089/ars.2010.3301 No, 2014, Targeting Nrf2 signaling to combat chemoresistance, J. Cancer. Prev., 19, 111, 10.15430/JCP.2014.19.2.111 Kim, 2008, Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin, Lung Canc., 60, 47, 10.1016/j.lungcan.2007.09.021 Singh, 2008, RNAi mediated silencing of Nrf2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy, Cancer. Res., 68, 7975, 10.1158/0008-5472.CAN-08-1401 Solis, 2010, Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features, Clin. Cancer. Res., 16, 3743, 10.1158/1078-0432.CCR-09-3352 Li, 2002, AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival, J. Biol. Chem., 277, 11352, 10.1074/jbc.M109062200 Héliez, 2003, Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells, Oncogene, 22, 3260, 10.1038/sj.onc.1206409 O'Reilly, 2005, Redox activation of p21Cip1/WAF1/Sdi1: a multifunctional regulator of cell survival and death, Antioxid. Redox. Sig., 7, 108, 10.1089/ars.2005.7.108 Toledano, 2009, The guardian recruits cops: the p53-p21 axis delegates prosurvival duties to the Keap1-Nrf2 stress pathway, Mol. Cell., 34, 637, 10.1016/j.molcel.2009.06.005 Xia, 2011, Cytoplasmic p21 is a potential predictor for cisplatin sensitivity in ovarian cancer, BMC Canc., 11, 399, 10.1186/1471-2407-11-399 Koster, 2010, Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer, J. Clin. Invest., 120, 3594, 10.1172/JCI41939 Vurusaner, 2012, Tumor suppressor genes and ROS: complex networks of interactions, Free Radic. Biol. Med., 52, 7, 10.1016/j.freeradbiomed.2011.09.035