Novel prognostic value and potential utility of opioid receptor gene methylation in liquid biopsy for oral cavity cancer

Arantes, 2014, Methylation as a biomarker for head and neck cancer, Oral Oncol, 50, 587, 10.1016/j.oraloncology.2014.02.015 Kang, 2015, Emerging biomarkers in head and neck cancer in the era of genomics, Nat Rev Clin Oncol, 12, 11, 10.1038/nrclinonc.2014.192 Bose, 2013, Head and neck cancer: from anatomy to biology, Int J Cancer, 133, 10.1002/ijc.28112 Lappano, 2011, G protein-coupled receptors: novel targets for drug discovery in cancer, Nat Rev Drug Discov, 10, 10.1038/nrd3320 Latek, 2013, Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison, PLoS One, 8, 10.1371/journal.pone.0056742 Hanson, 2009, Discovery of new GPCR biology: one receptor structure at a time, Structure, 17, 8, 10.1016/j.str.2008.12.003 Misawa, 2015, Aberrant methylation inactivates somatostatin and somatostatin receptor type 1 in head and neck squamous cell carcinoma, PLoS One, 10, 10.1371/journal.pone.0118588 Misawa, 2008, Epigenetic inactivation of galanin receptor 1 in head and neck cancer, Clin Cancer Res, 14, 10.1158/1078-0432.CCR-07-4673 Misawa, 2014, Tumor suppressor activity and inactivation of galanin receptor type 2 by aberrant promoter methylation in head and neck cancer, Cancer, 120, 10.1002/cncr.28411 Misawa, 2018, Association of TET3 epigenetic inactivation with head and neck cancer, Oncotarget, 9, 10.18632/oncotarget.25333 Misawa, 2019, 5-Hydroxymethylcytosine and ten-eleven translocation dioxygenases in head and neck carcinoma, J Cancer, 10, 10.7150/jca.34806 Wu, 2018, Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid Growth Factor Receptor (OGFr), Mol Cell Proteomics, 17, 10.1074/mcp.RA117.000277 Bortsov, 2012, mu-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer, Anesthesiology, 116, 896, 10.1097/ALN.0b013e31824b96a1 Krishnan, 2014, Insights into the origin of nematode chemosensory GPCRs: putative orthologs of the Srw family are found across several phyla of protostomes, PLoS One, 9, 10.1371/journal.pone.0093048 Bar-Shavit, 2016, G Protein-Coupled receptors in cancer, Int J Mol Sci, 10.3390/ijms17081320 Ji, 2017, Elevated OPRD1 promoter methylation in Alzheimer's disease patients, PLoS One, 12, 10.1371/journal.pone.0172335 Ji, 2015, OPRK1 promoter hypermethylation increases the risk of Alzheimer's disease, Neurosci Lett, 606, 10.1016/j.neulet.2015.08.027 Ruggeri, 2015, Association of protein phosphatase PPM1G with alcohol use disorder and brain activity during behavioral control in a genome-wide methylation analysis, Am J Psychiatry, 172, 543, 10.1176/appi.ajp.2014.14030382 Viet, 2014, Demethylating drugs as novel analgesics for cancer pain, Clin Cancer Res, 20, 10.1158/1078-0432.CCR-14-0901 Wagley, 2017, Epigenetic activation of mu-opioid receptor gene via increased expression and function of mitogen- and stress-activated protein kinase 1, Mol Pharmacol, 91, 10.1124/mol.116.106567 Herceg, 2007, Genetic and epigenetic alterations as biomarkers for cancer detection, diagnosis and prognosis, Mol Oncol, 1, 26, 10.1016/j.molonc.2007.01.004 Cheng, 2019, Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials, Signal Transduct Target Ther, 4, 62, 10.1038/s41392-019-0095-0 Lianidou, 2021, Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook, Mol Oncol, 15, 10.1002/1878-0261.12978 Nassar, 2021, Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction, Clin Epigenetics, 13, 111, 10.1186/s13148-021-01095-5 de Vos, 2017, Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients, Clin Epigenetics, 9, 125, 10.1186/s13148-017-0425-4 Zavridou, 2020, Direct comparison of size-dependent versus EpCAM-dependent CTC enrichment at the gene expression and DNA methylation level in head and neck squamous cell carcinoma, Sci Rep, 10, 10.1038/s41598-020-63055-y Misawa, 2020, Long interspersed nuclear element 1 hypomethylation has novel prognostic value and potential utility in liquid biopsy for oral cavity cancer, Biomark Res, 8, 53, 10.1186/s40364-020-00235-y Rasmussen, 2016, Role of TET enzymes in DNA methylation, development, and cancer, Genes Dev, 30 Scourzic, 2015, TET proteins and the control of cytosine demethylation in cancer, Genome Med, 7, 9, 10.1186/s13073-015-0134-6