Novel phenyl-urea derivatives as dual-target ligands that can activate both GK and PPARγ

Acta Pharmaceutica Sinica B - Tập 2 - Trang 588-597 - 2012
Lijian Zhang1, Kang Tian1, Yongqiang Li2, Lei Lei3, Aifang Qin1, Lijuan Zhang1, Hongrui Song1, Lianchao Huo2, Lijing Zhang2, Xiaofeng Jin2, Zhufang Shen3, Zhiqiang Feng2
1School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China
2Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
3Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China

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