Novel inhibitor candidates of TRPV2 prevent damage of dystrophic myocytes and ameliorate against dilated cardiomyopathy in a hamster model

Oncotarget - Tập 9 Số 18 - Trang 14042-14057 - 2018
Yuko Iwata1, Yoshimi Katayama2,3, Yasushi Okuno4, Shigeo Wakabayashi5,6
1Departments of Molecular Physiology and Clinical Research, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan
2Pharmacological Research Laboratories, Drug Safety Testing Center Co., Ltd., Higashimatsuyama, Saitama, Japan; Present affiliation: Biological Research Laboratories, Nissan Chemical Industries, Ltd, Shiraoka, Saitama, Japan
3Present affiliation: Biological Research Laboratories, Nissan Chemical Industries, Ltd, Shiraoka, Saitama, Japan
4Department of Clinical System Onco-Informatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan
5Departments of Molecular Physiology and Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan; Present affiliation: Department of Pharmocology, Osaka Medical Collage, Takatsuki, Osaka, Japan
6Present affiliation: Department of Pharmocology, Osaka Medical Collage, Takatsuki, Osaka, Japan

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