Novel inhibitor candidates of TRPV2 prevent damage of dystrophic myocytes and ameliorate against dilated cardiomyopathy in a hamster model
Tóm tắt
Từ khóa
Tài liệu tham khảo
McKenna, 2005, New insights into the pathology of inherited cardiomyopathy, Heart, 91, 257, 10.1136/hrt.2004.040337
Graham, 2002, Molecular mechanisms of inherited cardiomyopathies, Physiological Reviews, 82, 945, 10.1152/physrev.00012.2002
Seidman, 2001, The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms, Cell, 104, 557, 10.1016/S0092-8674(01)00242-2
Sanes, 1998, Progressive muscular dystrophy in alpha-sarcoglycan-deficient mice, The Journal of Cell Biology, 142, 1461, 10.1083/jcb.142.6.1461
Campbell, 1995, Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage, Cell, 80, 675, 10.1016/0092-8674(95)90344-5
Hayashizaki, 1997, Identification of the Syrian hamster cardiomyopathy gene, Human Molecular Genetics, 6, 601, 10.1093/hmg/6.4.601
Kahl, 1989, Association of dystrophin and an integral membrane glycoprotein, Nature, 338, 259, 10.1038/338259a0
Tinsley, Blake, Zuellig, Davies. Increasing complexity of the dystrophin-associated protein complex. Proceedings of the National Academy of Sciences of the United States of America. 1994; 91:pp. 8307–8313.
Campbell, 1993, A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin, The Journal of Cell Biology, 122, 809, 10.1083/jcb.122.4.809
Allard, 2000, Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels, Proc Natl Acad Sci U S A, 97, 4950, 10.1073/pnas.97.9.4950
Opas, 1997, Functions of dystrophin and dystrophin associated proteins, Curr Opin Neurol, 10, 436, 10.1097/00019052-199710000-00014
Pozzan, 2001, Alteration in calcium handling at the subcellular level in mdx myotubes, J Biol Chem, 276, 4647, 10.1074/jbc.M006337200
Lansman, 1990, Calcium entry through stretch-inactivated ion channels in mdx myotubes, Nature, 344, 670, 10.1038/344670a0
Steinhardt, 1990, Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin, Science, 250, 673, 10.1126/science.2173137
Shigekawa, 2001, Stretch-activated cation channels in skeletal muscle myotubes from sarcoglycan-deficient hamsters, Am J Physiol Cell Physiol, 281, C690, 10.1152/ajpcell.2001.281.2.C690
Shigekawa, 2003, A novel mechanism of myocyte degeneration involving the Ca2+-permeable growth factor-regulated channel, The Journal of Cell Biology, 161, 957, 10.1083/jcb.200301101
Wakabayashi, 2009, Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models, Human Molecular Genetics, 18, 824, 10.1093/hmg/ddn408
Gailly, 2009, Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions, FEBS Lett, 583, 3600, 10.1016/j.febslet.2009.10.033
Wakabayashi, 2013, Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy, Cardiovasc Res, 99, 760, 10.1093/cvr/cvt163
Matsuda, 2011, Adult onset cardiac dilatation in a transgenic mouse line with Galβ1,3GalNAc α2,3-sialyltransferase II (ST3Gal-II) transgenes: a new model for dilated cardiomyopathy, Proc Jpn Acad Ser B Phys Biol Sci, 87, 550, 10.2183/pjab.87.550
Rassendren, 2007, Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate, Mol Pharmacol, 72, 1258, 10.1124/mol.107.037044
Kojima, 1997, Inhibition of proliferation of MCF-7 breast cancer cells by a blocker of Ca(2+)-permeable channel, Cell Calcium, 22, 75, 10.1016/S0143-4160(97)90107-X
Nilius, 1994, Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells, Cell Calcium, 15, 45, 10.1016/0143-4160(94)90103-1
Kurimoto, 2002, Lumin, a cyanine dye, enhances interleukin 12-dependent interferon gamma production by lipopolysaccharide-stimulated mouse splenocytes, Biological & Pharmaceutical Bulletin, 25, 1018, 10.1248/bpb.25.1018
Prevarsakaya, 2009, Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation, Biochim Biophys Acta, 1793, 528, 10.1016/j.bbamcr.2009.01.003
Hwang, 2007, Transient receptor potential V2 expressed in sensory neurons is activated by probenecid, Neurosci Lett, 425, 120, 10.1016/j.neulet.2007.08.035
Flores, 2008, TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons, J Neurosci, 28, 6231, 10.1523/JNEUROSCI.0504-08.2008
Lorenz, 2012, Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation, J Mol Cell Cardiol, 53, 134, 10.1016/j.yjmcc.2012.04.011
Lorenz, 2014, Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance, Am J Physiol Heart Circ Physiol, 306, H574, 10.1152/ajpheart.00854.2013
Caterina, 2004, 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3, J Neurosci, 24, 5177, 10.1523/JNEUROSCI.0934-04.2004
Julius, 1999, A capsaicin-receptor homologue with a high threshold for noxious heat, Nature, 398, 436, 10.1038/18906
Tominaga, 2010, Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice, J Neurosci, 30, 16536, 10.1523/JNEUROSCI.4426-10.2010
Constantin, 2013, Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of alpha1-syntrophin and PLC/PKC in SOCE regulation, Am J Physiol Cell Physiol, 304, C881, 10.1152/ajpcell.00182.2012
Naruse, 2014, TRPV2 is critical for the maintenance of cardiac structure and function in mice, Nat Commun, 5, 3932, 10.1038/ncomms4932
Kimoto, 1992, Activation of mouse macrophages byandtreatment with a cyanine dye, lumin, Journal of Photochemistry and Photobiology B: Biology, 13, 295, 10.1016/1011-1344(92)85069-7
Mito, 1996, Photodynamic efficiency of macrophage activity using a photosensitizer, lumin, with near-IR laser light for photoimmunotherapy of a cancer, Frontiers of Medical and Biological Engineering, 7, 81
Wakabayashi, 2008, Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure, Circulation Research, 103, 891, 10.1161/CIRCRESAHA.108.175141
Wakabayashi, 2005, Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells, Biochem Pharmacol, 70, 740, 10.1016/j.bcp.2005.05.034
Sigworth, 1981, Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflugers Arch, 391, 85, 10.1007/BF00656997
Gordon, 2010, Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate, J Neurosci, 30, 13338, 10.1523/JNEUROSCI.2108-10.2010
Sokabe, 1993, Involvement of stretch-activated ion channels in Ca2+ mobilization to mechanical stretch in endothelial cells, Am J Physiol, 264, C1037, 10.1152/ajpcell.1993.264.4.C1037