Novel Presentation of Cardiotoxicity and Other Complications in Tricyclic Antidepressant Poisoning.

CUREUS JOURNAL OF MEDICAL SCIENCE - Tập 13 Số 8 - Trang e17181 - 2021
Hiep Nguyen1, Ariel Kidron2, Christopher Ghildyal3, Shriya Veluri4, Nghi Nguyen5, Quan Nguyen6, Hoang Nguyen7
1Osteopathic Medicine, Nova Southeastern University Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
2Emergency Medicine, Nova Southeastern University Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
3Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
4School of Interdisciplinary Studies, University of Texas at Dallas, Richardson, USA
5Medicine, University of Saint Thomas, Houston, USA.
6Clinical Sciences, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
7Basic Sciences, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.

Tóm tắt

Tricyclic antidepressant (TCA) is a known frequently used and highly potent antidepressant that serves as an unsuspecting source of acute human poisoning. We present a case of an Asian female in her mid-30s who suffered TCA toxidrome that manifested as severe cardiovascular toxicities including arrhythmia characterized by QT elongation that was managed emergently. Hemodynamics and ECG findings improved gradually following appropriate therapy in the intensive care unit. Following two days of treatment, the patient regained consciousness and after seven days the patient made a full clinical recovery and was discharged with no residual neurological effects. The relevant medical literature on TCA poisoning is reviewed.

Từ khóa

#cardiology #clinical psychiatry #critical care #disaster medicine #emergency critical care #emergency medicine #neurology #psychiatric pharmacology

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