Notch signaling in the brain: In good and bad times
Tài liệu tham khảo
Alagille, 1975, Hepatic ductular hypoplasia associated with characteristic facies, vertebral malformations, retarded physical, mental, and sexual development, and cardiac murmur, Journal of Pediatrics, 86, 63, 10.1016/S0022-3476(75)80706-2
Alberi, 2010, Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury, Stroke, 41, S64, 10.1161/STROKEAHA.110.595298
Alberi, 2011, Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks, Neuron, 69, 437, 10.1016/j.neuron.2011.01.004
Andersen, 2012, Non-canonical Notch signaling: emerging role and mechanism, Trends in Cell Biology, 22, 257, 10.1016/j.tcb.2012.02.003
Androutsellis-Theotokis, 2006, Notch signalling regulates stem cell numbers in vitro and in vivo, Nature, 442, 823, 10.1038/nature04940
Ann, 2012, Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein, J Biol Chem, 287, 36814, 10.1074/jbc.M112.356048
Arboleda-Velasquez, 2011, Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease, Proceedings of the National Academy of Sciences of the United States of America, 108, E128, 10.1073/pnas.1101964108
Arboleda-Velasquez, 2008, Linking Notch signaling to ischemic stroke, Proceedings of the National Academy of Sciences of the United States of America, 105, 4856, 10.1073/pnas.0709867105
Artavanis-Tsakonas, 1999, Notch signaling: cell fate control and signal integration in development, Science, 284, 770, 10.1126/science.284.5415.770
Arumugam, 2006, Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke, Nature Medicine, 12, 621, 10.1038/nm1403
Arumugam, 2011, Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke, Molecular Pharmacology, 80, 23, 10.1124/mol.111.071076
Ataman, 2008, Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling, Neuron, 57, 705, 10.1016/j.neuron.2008.01.026
Basak, 2012, Neurogenic subventricular zone stem/progenitor cells are Notch1-dependent in their active but not quiescent state, Journal of Neuroscience, 32, 5654, 10.1523/JNEUROSCI.0455-12.2012
Basak, 2007, Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression, European Journal of Neuroscience, 25, 1006, 10.1111/j.1460-9568.2007.05370.x
Bash, 1999, Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors, EMBO Journal, 18, 2803, 10.1093/emboj/18.10.2803
Becam, 2010, A role of receptor Notch in ligand cis-inhibition in Drosophila, Current Biology, 20, 554, 10.1016/j.cub.2010.01.058
Beffert, 2005, Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2, Neuron, 47, 567, 10.1016/j.neuron.2005.07.007
Bekinschtein, 2007, mTOR signaling in the hippocampus is necessary for memory formation, Neurobiology of Learning and Memory, 87, 303, 10.1016/j.nlm.2006.08.007
Ben Abdallah, 2010, Early age-related changes in adult hippocampal neurogenesis in C57 mice, Neurobiology of Aging, 31, 151, 10.1016/j.neurobiolaging.2008.03.002
Berezovska, 1999, Notch1 inhibits neurite outgrowth in postmitotic primary neurons, Neuroscience, 93, 433, 10.1016/S0306-4522(99)00157-8
Berezovska, 1998, Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease, Journal of Neuropathology and Experimental Neurology, 57, 738, 10.1097/00005072-199808000-00003
Bergami, 2009, Conditional deletion of TrkB alters adult hippocampal neurogenesis and anxiety-related behavior, Communicative and Integrative Biology, 2, 14, 10.4161/cib.2.1.7349
Bonini, 2011, Nuclear factor kappaB-dependent neurite remodeling is mediated by Notch pathway, Journal of Neuroscience, 31, 11697, 10.1523/JNEUROSCI.1113-11.2011
Breunig, 2007, Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus, Proceedings of the National Academy of Sciences of the United States of America, 104, 20558, 10.1073/pnas.0710156104
Brown, 2007, Heat shock proteins and protection of the nervous system, Annals of the New York Academy of Sciences, 1113, 147, 10.1196/annals.1391.032
Brown, 2003, Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis, European Journal of Neuroscience, 17, 2042, 10.1046/j.1460-9568.2003.02647.x
Bruel-Jungerman, 2009, Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus, PLoS ONE, 4, e7901, 10.1371/journal.pone.0007901
Calzavara, 2008, Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro, Journal of Cellular Biochemistry, 103, 1405, 10.1002/jcb.21527
Carlen, 2009, Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke, Nature Neuroscience, 12, 259, 10.1038/nn.2268
Chan, 2007, Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia, Blood, 110, 278, 10.1182/blood-2006-08-039883
Chao, 2005, lin-12 Notch functions in the adult nervous system of C. elegans, BMC Neuroscience, 6, 45, 10.1186/1471-2202-6-45
Chavez, 2002, Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1, Journal of Neuroscience, 22, 8922, 10.1523/JNEUROSCI.22-20-08922.2002
Chavez-Gutierrez, 2012, The mechanism of gamma-Secretase dysfunction in familial Alzheimer disease, Embo J, 31, 2261, 10.1038/emboj.2012.79
Chen, 2008, Atorvastatin promotes presenilin-1 expression and Notch1 activity and increases neural progenitor cell proliferation after stroke, Stroke, 39, 220, 10.1161/STROKEAHA.107.490946
Chen, 2008, Adult neurogenesis is functionally associated with AD-like neurodegeneration, Neurobiology of Disease, 29, 316, 10.1016/j.nbd.2007.09.005
Cheng, 2001, Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells, Journal of Immunology, 167, 4458, 10.4049/jimmunol.167.8.4458
Chevallier, 2005, Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation, American Journal of Pathology, 167, 151, 10.1016/S0002-9440(10)62962-8
Chi, 2012, Botch promotes neurogenesis by antagonizing Notch, Developmental Cell, 22, 707, 10.1016/j.devcel.2012.02.011
Childress, 2006, Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis, Current Biology, 16, 2228, 10.1016/j.cub.2006.09.031
Cisse, 2011, The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein, Journal of Biological Chemistry, 286, 29192, 10.1074/jbc.M110.208249
Conboy, 2007, Notch signalling becomes transiently attenuated during long-term memory consolidation in adult Wistar rats, Neurobiology of Learning and Memory, 88, 342, 10.1016/j.nlm.2007.04.006
Costa, 2003, Learning and memory deficits in Notch mutant mice, Current Biology, 13, 1348, 10.1016/S0960-9822(03)00492-5
Crowner, 2003, Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway, Current Biology, 13, 967, 10.1016/S0960-9822(03)00325-7
D‘Souza, 2008, The many facets of Notch ligands, Oncogene, 27, 5148, 10.1038/onc.2008.229
Dahlhaus, 2008, Notch1 signaling in pyramidal neurons regulates synaptic connectivity and experience-dependent modifications of acuity in the visual cortex, Journal of Neuroscience, 28, 10794, 10.1523/JNEUROSCI.1348-08.2008
Dai, 2010, Functional identification of neuroprotective molecules, PLoS ONE, 5, e15008, 10.1371/journal.pone.0015008
Dang, 2006, Notch3 signaling initiates choroid plexus tumor formation, Oncogene, 25, 487, 10.1038/sj.onc.1209074
de Bivort, 2009, Notch Signaling Is Required for Activity-Dependent Synaptic Plasticity at the Drosophila Neuromuscular Junction, Journal of Neurogenetics, 1, 10.1080/01677060902878481
de Celis, 1997, Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing, Development, 124, 3241, 10.1242/dev.124.17.3241
de la Pompa, 1997, Conservation of the Notch signalling pathway in mammalian neurogenesis, Development, 124, 1139, 10.1242/dev.124.6.1139
del Alamo, 2009, Notch signalling: receptor cis-inhibition to achieve directionality, Current Biology, 19, R683, 10.1016/j.cub.2009.07.025
Del Monte, 2007, Monitoring Notch1 activity in development: evidence for a feedback regulatory loop, Developmental Dynamics, 236, 2594, 10.1002/dvdy.21246
Dichgans, 2007, Genetics of ischaemic stroke, The Lancet Neurology, 6, 149, 10.1016/S1474-4422(07)70028-5
Ehm, 2010, RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus, Journal of Neuroscience, 30, 13794, 10.1523/JNEUROSCI.1567-10.2010
Eiraku, 2002, Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons, Journal of Biological Chemistry, 277, 25400, 10.1074/jbc.M110793200
Espinosa, 2002, p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR, Journal of Cell Science, 115, 1295, 10.1242/jcs.115.6.1295
Fassa, 2005, Notch 1 interacts with the amyloid precursor protein in a Numb-independent manner, Journal of Neuroscience Research, 82, 214, 10.1002/jnr.20642
Faure, 2011, Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease, Neurobiology of Aging, 32, 407, 10.1016/j.neurobiolaging.2009.03.009
Ferrari Toninelli, 2003, Long-lasting induction of Notch2 in the hippocampus of kainate-treated adult mice, Neuroreport, 14, 917, 10.1097/00001756-200305230-00003
Ferron, 2009, Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis, Journal of Neuroscience, 29, 14394, 10.1523/JNEUROSCI.3836-09.2009
Fischer, 2005, Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP, FASEB Journal, 19, 1451, 10.1096/fj.04-3395.com
Fortini, 1994, The suppressor of hairless protein participates in notch receptor signaling, Cell, 79, 273, 10.1016/0092-8674(94)90196-1
Franklin, 1999, Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1, Current Biology, 9, 1448, 10.1016/S0960-9822(00)80114-1
Fre, 2011, Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice, PLoS ONE, 6, e25785, 10.1371/journal.pone.0025785
Fryer, 2004, Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover, Molecular Cell, 16, 509, 10.1016/j.molcel.2004.10.014
Gaiano, 2002, The role of notch in promoting glial and neural stem cell fates, Annual Review of Neuroscience, 25, 471, 10.1146/annurev.neuro.25.030702.130823
Garaschuk, 2000, Large-scale oscillatory calcium waves in the immature cortex, Nature Neuroscience, 3, 452, 10.1038/74823
Gazave, 2009, Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes, BMC Evolutionary Biology, 9, 249, 10.1186/1471-2148-9-249
Ge, 2008, The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development, Proceedings of the National Academy of Sciences of the United States of America, 105, 1539, 10.1073/pnas.0702846105
Ge, 2004, Notch signaling in Drosophila long-term memory formation, Proceedings of the National Academy of Sciences of the United States of America, 101, 10172, 10.1073/pnas.0403497101
Gidday, 2006, Cerebral preconditioning and ischaemic tolerance, Nature Reviews Neuroscience, 7, 437, 10.1038/nrn1927
Giniger, 1998, A role for Abl in Notch signaling, Neuron, 20, 667, 10.1016/S0896-6273(00)81007-7
Glittenberg, 2006, Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis, EMBO Journal, 25, 4697, 10.1038/sj.emboj.7601337
Grandbarbe, 2003, Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process, Development, 130, 1391, 10.1242/dev.00374
Gustafsson, 2005, Hypoxia requires notch signaling to maintain the undifferentiated cell state, Developmental Cell, 9, 617, 10.1016/j.devcel.2005.09.010
Gutierrez, 2007, NOTCH and PI3K-AKT pathways intertwined, Cancer Cell, 12, 411, 10.1016/j.ccr.2007.10.027
Hanz, 2003, Axoplasmic importins enable retrograde injury signaling in lesioned nerve, Neuron, 40, 1095, 10.1016/S0896-6273(03)00770-0
Hashimoto-Torii, 2008, Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex, Neuron, 60, 273, 10.1016/j.neuron.2008.09.026
Herz, 2006, Reelin, lipoprotein receptors and synaptic plasticity, Nature Reviews Neuroscience, 7, 850, 10.1038/nrn2009
Hicks, 2002, A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling, Journal of Neuroscience Research, 68, 655, 10.1002/jnr.10263
Hoeck, 2010, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun, Nature Neuroscience, 13, 1365, 10.1038/nn.2644
Hoeffer, 2008, Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior, Neuron, 60, 832, 10.1016/j.neuron.2008.09.037
Hoey, 2009, Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production, Journal of Neuroscience, 29, 4442, 10.1523/JNEUROSCI.6017-08.2009
Hofmann, 2007, Notch signaling in blood vessels: who is talking to whom about what?, Circulation Research, 100, 1556, 10.1161/01.RES.0000266408.42939.e4
Hori, 2011, Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal, Journal of Cell Biology, 195, 1005, 10.1083/jcb.201104146
Hou, 2004, Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression, Journal of Neuroscience, 24, 6352, 10.1523/JNEUROSCI.0995-04.2004
Huang, 2004, Identification of p53 regulators by genome-wide functional analysis, Proceedings of the National Academy of Sciences of the United States of America, 101, 3456, 10.1073/pnas.0308562100
Huenniger, 2010, Notch1 signaling is mediated by importins alpha 3, 4, and 7, Cellular and Molecular Life Sciences, 67, 3187, 10.1007/s00018-010-0378-7
Imayoshi, 2011, The role of Notch signaling in adult neurogenesis, Molecular Neurobiology, 44, 7, 10.1007/s12035-011-8186-0
Imayoshi, 2010, Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains, Journal of Neuroscience, 30, 3489, 10.1523/JNEUROSCI.4987-09.2010
Ishikawa, 2008, Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7, Oncogene, 27, 6164, 10.1038/onc.2008.216
Ishikura, 2005, Notch-1 activation and dendritic atrophy in prion disease, Proceedings of the National Academy of Sciences of the United States of America, 102, 886, 10.1073/pnas.0408612101
Iso, 2003, HES and HERP families: multiple effectors of the Notch signaling pathway, Journal of Cellular Physiology, 194, 237, 10.1002/jcp.10208
Jafar-Nejad, 2002, Numb: Adapting” notch for endocytosis, Developmental Cell, 3, 155, 10.1016/S1534-5807(02)00228-9
Jaskelioff, 2011, Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice, Nature, 469, 102, 10.1038/nature09603
Johnson, 2011, HIF takes it up a notch, Science Signaling, 4, pe33, 10.1126/scisignal.2002277
Joutel, 2000, Splice site mutation causing a seven amino acid Notch3 in-frame deletion in CADASIL, Neurology, 54, 1874, 10.1212/WNL.54.9.1874
Kameda, 2012, Activation of latent precursors in the hippocampus is dependent on long-term potentiation, Translational Psychiatry, 2, e72, 10.1038/tp.2011.70
Kawai, 2005, Changes in the expression of Hes5 and Mash1 mRNA in the adult rat dentate gyrus after transient forebrain ischemia, Neuroscience Letters, 380, 17, 10.1016/j.neulet.2005.01.005
Kempermann, 2002, Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task, European Journal of Neuroscience, 16, 129, 10.1046/j.1460-9568.2002.02042.x
Kim, 2007, Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction, Biochimica et Biophysica Acta, 1773, 736, 10.1016/j.bbamcr.2007.02.001
Koeller, 2008, Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity, Neurobiology of Disease, 31, 230, 10.1016/j.nbd.2008.04.010
Konietzko, 2010, Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories, Neurobiology of Aging, 31, 58, 10.1016/j.neurobiolaging.2008.03.001
Koo, 2005, Mind bomb 1 is essential for generating functional Notch ligands to activate Notch, Development, 132, 3459, 10.1242/dev.01922
Koo, 2007, An obligatory role of mind bomb-1 in notch signaling of mammalian development, PLoS ONE, 2, e1221, 10.1371/journal.pone.0001221
Kopan, 2009, The canonical Notch signaling pathway: unfolding the activation mechanism, Cell, 137, 216, 10.1016/j.cell.2009.03.045
Kumar, 2001, EGF receptor and Notch signaling act upstream of Eyeless/Pax6 to control eye specification, Cell, 104, 687, 10.1016/S0092-8674(01)00265-3
Kurisu, 2010, Polarized targeting of DNER into dendritic plasma membrane in hippocampal neurons depends on endocytosis, Journal of Neurochemistry, 113, 1598
Kwon, 2011, Notch post-translationally regulates beta-catenin protein in stem and progenitor cells, Nature Cell Biology, 13, 1244, 10.1038/ncb2313
Kyriazis, 2010, Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel, Journal of Biological Chemistry, 285, 6811, 10.1074/jbc.M109.074690
Le Borgne, 2005, Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila, PLoS Biology, 3, e96, 10.1371/journal.pbio.0030096
Le Gall, 2008, Molecular separation of two signaling pathways for the receptor, Notch, Developmental Biology, 313, 556, 10.1016/j.ydbio.2007.10.030
Leal, 2012, Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Abeta metabolism, Biochimica et Biophysica Acta, 1823, 227, 10.1016/j.bbamcr.2011.09.014
Lefort, 2007, Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases, Genes and Development, 21, 562, 10.1101/gad.1484707
Li, 2012, Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1, Stem Cells, 30, 741, 10.1002/stem.1030
Lie, 2005, Wnt signalling regulates adult hippocampal neurogenesis, Nature, 437, 1370, 10.1038/nature04108
Lieber, 2011, DSL-Notch signaling in the Drosophila brain in response to olfactory stimulation, Neuron, 69, 468, 10.1016/j.neuron.2010.12.015
Limbourg, 2005, Essential role of endothelial Notch1 in angiogenesis, Circulation, 111, 1826, 10.1161/01.CIR.0000160870.93058.DD
Lindsell, 1996, Expression patterns of Jagged, Delta1, Notch1. Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development, Molecular and Cellular Neurosciences, 8, 14, 10.1006/mcne.1996.0040
Lindsell, 1995, Jagged: a mammalian ligand that activates Notch1, Cell, 80, 909, 10.1016/0092-8674(95)90294-5
Liu, 2011, MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway, PLoS ONE, 6, e23461, 10.1371/journal.pone.0023461
Lou, 2012, miR-210 activates notch signaling pathway in angiogenesis induced by cerebral ischemia, Molecular and Cellular Biochemistry, 370, 45, 10.1007/s11010-012-1396-6
Lugert, 2010, Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging, Cell Stem Cell, 6, 445, 10.1016/j.stem.2010.03.017
Lugert, 2012, Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1(high) intermediate progenitors, Nature Communications, 3, 670, 10.1038/ncomms1670
Matsumoto, 2011, Fbxw7-dependent degradation of Notch is required for control of stemness” and neuronal-glial differentiation in neural stem cells, Journal of Biological Chemistry, 286, 13754, 10.1074/jbc.M110.194936
Matsuno, 2009, The Drosophila cell adhesion molecule klingon is required for long-term memory formation and is regulated by Notch, Proceedings of the National Academy of Sciences of the United States of America, 106, 310, 10.1073/pnas.0807665106
Meffert, 2005, Physiological functions for brain NF-kappaB, Trends in Neurosciences, 28, 37, 10.1016/j.tins.2004.11.002
Meffert, 2003, NF-kappa B functions in synaptic signaling and behavior, Nature Neuroscience, 6, 1072, 10.1038/nn1110
Miller, 2009, cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition, Current Biology, 19, 1378, 10.1016/j.cub.2009.06.042
Mizutani, 2007, Differential Notch signalling distinguishes neural stem cells from intermediate progenitors, Nature, 449, 351, 10.1038/nature06090
Moehlmann, 2002, Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production, Proceedings of the National Academy of Sciences of the United States of America, 99, 8025, 10.1073/pnas.112686799
Mukherjee, 2011, Interaction between Notch and Hif-alpha in development and survival of Drosophila blood cells, Science, 332, 1210, 10.1126/science.1199643
Mumm, 2000, A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1, Molecular Cell, 5, 197, 10.1016/S1097-2765(00)80416-5
Muskavitch, 1994, Delta-notch signaling and Drosophila cell fate choice, Developmental Biology, 166, 415, 10.1006/dbio.1994.1326
Nagarsheth, 2006, Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease, Journal of the Neurological Sciences, 244, 111, 10.1016/j.jns.2006.01.007
Nichols, 2007, DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur, Journal of Cell Biology, 176, 445, 10.1083/jcb.200609014
Nishimura, 2006, Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2, Molecular Biology of the Cell, 17, 1273, 10.1091/mbc.E05-07-0700
Nye, 1995, Developmental signaling. Vertebrate ligands for Notch, Current Biology, 5, 966, 10.1016/S0960-9822(95)00189-8
Nyfeler, 2005, Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal, EMBO Journal, 24, 3504, 10.1038/sj.emboj.7600816
Ohtsuka, 2006, Visualization of embryonic neural stem cells using Hes promoters in transgenic mice, Molecular and Cellular Neurosciences, 31, 109, 10.1016/j.mcn.2005.09.006
Okochi, 2002, Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1, EMBO Journal, 21, 5408, 10.1093/emboj/cdf541
Oya, 2009, Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury, Neuroscience, 158, 683, 10.1016/j.neuroscience.2008.10.043
Palomero, 2007, Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia, Nature Medicine, 13, 1203, 10.1038/nm1636
Palop, 2009, Epilepsy and cognitive impairments in Alzheimer disease, Archives of Neurology, 66, 435, 10.1001/archneurol.2009.15
Parks, 2000, Ligand endocytosis drives receptor dissociation and activation in the Notch pathway, Development, 127, 1373, 10.1242/dev.127.7.1373
Parr-Sturgess, 2010, Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event, Biochemical Journal, 432, 283, 10.1042/BJ20100321
Perumalsamy, 2009, A hierarchical cascade activated by non-canonical Notch signaling and the mTOR-Rictor complex regulates neglect-induced death in mammalian cells, Cell Death and Differentiation, 16, 879, 10.1038/cdd.2009.20
Pierfelice, 2011, Notch3 activation promotes invasive glioma formation in a tissue site-specific manner, Cancer Research, 71, 1115, 10.1158/0008-5472.CAN-10-0690
Pierre, 2001, Mobilization of the cell adhesion glycoprotein F3/contactin to axonal surfaces is activity dependent, European Journal of Neuroscience, 14, 645, 10.1046/j.0953-816x.2001.01682.x
Placanica, 2009, Gender- and age-dependent gamma-secretase activity in mouse brain and its implication in sporadic Alzheimer disease, PLoS ONE, 4, e5088, 10.1371/journal.pone.0005088
Rebay, 1991, Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor, Cell, 67, 687, 10.1016/0092-8674(91)90064-6
Redmond, 2000, Nuclear Notch1 signaling and the regulation of dendritic development, Nature Neuroscience, 3, 30, 10.1038/71104
Rochefort, 2002, Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory, Journal of Neuroscience, 22, 2679, 10.1523/JNEUROSCI.22-07-02679.2002
Rodriguez, 2008, Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease, PLoS ONE, 3, e2935, 10.1371/journal.pone.0002935
Rodriguez, 2009, Impaired cell proliferation in the subventricular zone in an Alzheimer's disease model, Neuroreport, 20, 907, 10.1097/WNR.0b013e32832be77d
Roncarati, 2002, The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling, Proceedings of the National Academy of Sciences of the United States of America, 99, 7102, 10.1073/pnas.102192599
Ronchini, 2001, Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic), Molecular and Cellular Biology, 21, 5925, 10.1128/MCB.21.17.5925-5934.2001
Sakamoto, 2011, Continuous neurogenesis in the adult forebrain is required for innate olfactory responses, Proceedings of the National Academy of Sciences of the United States of America, 108, 8479, 10.1073/pnas.1018782108
Sanalkumar, 2010, Non-canonical activation of Notch signaling/target genes in vertebrates, Cellular and Molecular Life Sciences, 67, 2957, 10.1007/s00018-010-0391-x
Sato, 2012, Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice, PLoS ONE, 7, e48180, 10.1371/journal.pone.0048180
Saura, 2004, Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration, Neuron, 42, 23, 10.1016/S0896-6273(04)00182-5
Sawe, 2008, Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke, Journal of Neuroscience Research, 86, 1659, 10.1002/jnr.21604
Schroeter, 1998, Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain, Nature, 393, 382, 10.1038/30756
Seidel, 2010, A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha, Brain, 133, 983, 10.1093/brain/awq042
Selkoe, 2007, Presenilin: running with scissors in the membrane, Cell, 131, 215, 10.1016/j.cell.2007.10.012
Sestan, 1999, Contact-dependent inhibition of cortical neurite growth mediated by notch signaling, Science, 286, 741, 10.1126/science.286.5440.741
Shepherd, 2010, Notch and delta mRNAs in early-stage and mid-stage drosophila embryos exhibit complementary patterns of protein-producing potentials, Developmental Dynamics, 239, 1220, 10.1002/dvdy.22262
Shepherd, 2009, Notch mRNA expression in Drosophila embryos is negatively regulated at the level of mRNA 3’ processing, PLoS ONE, 4, e8063, 10.1371/journal.pone.0008063
Shimada, 2011, Proliferating reactive astrocytes are regulated by Notch-1 in the peri-infarct area after stroke, Stroke, 42, 3231, 10.1161/STROKEAHA.111.623280
Sibbe, 2009, Reelin and Notch1 cooperate in the development of the dentate gyrus, Journal of Neuroscience, 29, 8578, 10.1523/JNEUROSCI.0958-09.2009
Sibbe, 2012, Experimental epilepsy affects Notch1 signalling and the stem cell pool in the dentate gyrus, Eur J Neurosci, 36, 3643, 10.1111/j.1460-9568.2012.08279.x
Smith, 2012, Generation and characterization of a Notch1 signaling-specific reporter mouse line, Genesis, 50, 700, 10.1002/dvg.22030
Song, 2010, Neural and synaptic defects in slytherin, a zebrafish model for human congenital disorders of glycosylation, PLoS ONE, 5, e13743, 10.1371/journal.pone.0013743
Souilhol, 2006, Nas transgenic mouse line allows visualization of Notch pathway activity in vivo, Genesis, 44, 277, 10.1002/dvg.20208
Speese, 2007, Wnts: up-and-coming at the synapse, Trends in Neurosciences, 30, 268, 10.1016/j.tins.2007.04.003
Stanley, 2007, Regulation of Notch signaling by glycosylation, Current Opinion in Structural Biology, 17, 530, 10.1016/j.sbi.2007.09.007
Steiner, 1999, Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease, European Archives of Psychiatry and Clinical Neuroscience, 249, 266, 10.1007/s004060050098
Steiner, 2001, A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques, Journal of Biological Chemistry, 276, 7233, 10.1074/jbc.M007183200
Stoll, 1998, Inflammation and glial responses in ischemic brain lesions, Progress in Neurobiology, 56, 149, 10.1016/S0301-0082(98)00034-3
Stump, 2002, Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain, Mechanisms of Development, 114, 153, 10.1016/S0925-4773(02)00043-6
Swiatek, 1994, Notch1 is essential for postimplantation development in mice, Genes and Development, 8, 707, 10.1101/gad.8.6.707
Tagami, 2008, Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1, Molecular and Cellular Biology, 28, 165, 10.1128/MCB.00863-07
Takeshita, 2007, Critical role of endothelial Notch1 signaling in postnatal angiogenesis, Circulation Research, 100, 70, 10.1161/01.RES.0000254788.47304.6e
Tanigaki, 2001, Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate, Neuron, 29, 45, 10.1016/S0896-6273(01)00179-9
Timsit, 1999, Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?, European Journal of Neuroscience, 11, 263, 10.1046/j.1460-9568.1999.00434.x
Tokunaga, 2004, Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain, Journal of Neurochemistry, 90, 142, 10.1111/j.1471-4159.2004.02470.x
Vaccari, 2005, The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking, Developmental Cell, 9, 687, 10.1016/j.devcel.2005.09.019
Vaccari, 2008, Endosomal entry regulates Notch receptor activation in Drosophila melanogaster, Journal of Cell Biology, 180, 755, 10.1083/jcb.200708127
van Praag, 1999, Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus, Nature Neuroscience, 2, 266, 10.1038/6368
Varela-Nallar, 2010, Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses, Proceedings of the National Academy of Sciences of the United States of America, 107, 21164, 10.1073/pnas.1010011107
Varnum-Finney, 2000, Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling, Journal of Cell Science, 113, 4313, 10.1242/jcs.113.23.4313
Vooijs, 2007, Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE, Development, 134, 535, 10.1242/dev.02733
Wang, 2009, Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo, Journal of Cerebral Blood Flow and Metabolism, 29, 1644, 10.1038/jcbfm.2009.83
Wang, 2004, Involvement of Notch signaling in hippocampal synaptic plasticity, Proceedings of the National Academy of Sciences of the United States of America, 101, 9458, 10.1073/pnas.0308126101
Weeber, 2002, Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning, Journal of Biological Chemistry, 277, 39944, 10.1074/jbc.M205147200
Wei, 2011, Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia, Stroke, 42, 2589, 10.1161/STROKEAHA.111.614834
Wolfe, 2012, gamma-Secretase inhibitors and modulators for Alzheimer's disease, Journal of Neurochemistry, 120, 89, 10.1111/j.1471-4159.2011.07501.x
Wong, 2004, Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation, Journal of Biological Chemistry, 279, 12876, 10.1074/jbc.M311652200
Woo, 2009, Alzheimer's disease and Notch signaling, Biochemical and Biophysical Research Communications, 390, 1093, 10.1016/j.bbrc.2009.10.093
Wu, 2011, Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent beta-amyloid generation, Cell, 147, 615, 10.1016/j.cell.2011.09.036
Xin, 2006, Bone marrow stromal cells induce BMP2/4 production in oxygen-glucose-deprived astrocytes, which promotes an astrocytic phenotype in adult subventricular progenitor cells, Journal of Neuroscience Research, 83, 1485, 10.1002/jnr.20834
Yagi, 2012, Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the Notch signaling pathway, Journal of Biological Chemistry, 287, 24356, 10.1074/jbc.M112.365643
Yang, 2012, Activation of canonical notch signaling pathway is involved in the ischemic tolerance induced by sevoflurane preconditioning in mice, Anesthesiology, 117, 996, 10.1097/ALN.0b013e31826cb469
Yang, 2004, Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway, Developmental Biology, 269, 81, 10.1016/j.ydbio.2004.01.014
Yoon, 2008, Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells, Neuron, 58, 519, 10.1016/j.neuron.2008.03.018
Yoon, 2012, Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway, Molecular Brain, 5, 40, 10.1186/1756-6606-5-40
Yu, 2001, APP processing and synaptic plasticity in presenilin-1 conditional knockout mice, Neuron, 31, 713, 10.1016/S0896-6273(01)00417-2
Zheng, 2012, Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins, Journal of Biological Chemistry, 287, 20356, 10.1074/jbc.M112.349738
Zhou, 2008, Notch-dependent control of myelopoiesis is regulated by fucosylation, Blood, 112, 308, 10.1182/blood-2007-11-115204