Nosocomial pneumonia: Comparative multicentre trial between monotherapy with cefotaxime and treatment with antibiotic combinations

Manuel L. Fernández-Guerrero1, Francesc Gudiol1, A Rodríguez‐Torres1, C Arnau1, Luís Valdés2, Carlos Vallvé3
1Division of Infectious Disease, Fundación Jiménez Díaz, Madrid, Spain
2Infectious Disease Service, Hospital Príncipes de España, Barcelona, Spain
3Department of Clinical Microbiology, Hospital Clínico, Valladolid, Spain

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Centers for Disease Control National Nosocomial Infections Study Report. Annual Summary 1984. MMWR 35 (1986) 17ss-29ss.

Garibaldi, R. A., Britt, M. R., Coleman, M. L., Reading, J. C., Pace, N. L. Risk factors for postoperative pneumonia. Am. J. Med. 70 (1981) 677–680.

Gross, P. A., Neu, H. C., Aswaspokee, P., Van Antwerpen, C., Aswapokee, N. Deaths from nosocomial infections: experience in a university hospital and a community hospital. Am. J. Med. 68 (1980) 219–223.

Wimberley, N., Faling, L. J., Bartlett, J. G. A fiberoptic bronchoscopy technique to obtain uncontaminated lower airway secretions for bacterial culture. Am. Rev. Respir. Dis. 119 (1979) 337–343.

Chastre, J., Viau, F., Brun, P., Pierre, J., Dauge, M. C., Bouchana, A., Akesbi, A., Gibert, C. Prospective evaluation of the protected specimen brush for the diagnosis of pulmonary infections in ventilated patients. Am. Rev. Respir. Dis. 130 (1984) 924–929.

Pennington, J. E. Nosocomial respiratory infection. In:Mandell, G. L., Douglas, R. G., Bennett, J. E. (eds.): Principles and practice of infectious disease. Third edition. Churchill Livingstone, New York (1990) pp. 2199–2205.

Organización Mundial de la Salud: Clasificación Internacional de Enfermedades. Washington 1978.

Catálogo de especialidades farmacéuticas. Departamento Técnico. Consejo General de Colegios Oficiales de Farmacéuticos. Madrid 1989.

Eliopoulos, G. M., Eliopoulos, C. T. Antibiotic combinations: should they be tested? Clin. Microbiol. Rev. 1 (1988) 139–156.

Todd, P. A., Brogden, R. N. Cefotaxime. An update of its pharmacology and therapeutic use. Drugs 40 (1990) 608–651.

Cone, L. A., Woodard, D. R., Stolzman, D. S., Byrd, R. G. Ceftazidime versus tobramycin-ticarcillin in the treatment of pneumonia and bacteremia. Antimicrob. Agents Chemother. 28 (1985) 33–36.

Greenberg, R. N., Reilly, P. M., Luppen, K. L., Bollinger, M., Mc Millan, R. Aztreonam therapy for gram-negative pneumonia. Am. J. Med. 78s (1985) 31–33.

Salata, R. A., Gebhart, R. L., Palmer, D. L., Wade, B. H., Scheld, W. M., Groschel, D. H. M., Wenzel, R. P., Mandell, G. L., Duma, R. J. Pneumonia treated with imipenem/cilastin. Am. J. Med. 78s (1985) 104–109.

Carmine, A. A., Brogden, R. N., Heel, R. C., Speight, T. M., Avery, G. S. Cefotaxime: a review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs 25 (1983) 223–289.

Reeves, J. H., Russell, G. M., Cade, J. F., McDonald, M. Comparison of ceftriaxone with cefotaxime in serious chest infections. Chest 96 (1989) 1292–1297.

Pallarés, R., Gudiol, F., Liñares, J., Viladrich, P. Bacteremic pneumonia caused by penicillin-resistant pneumococci. N. Engl. J. Med. 318 (1988) 124–128.

Moore, R. D., Smith, C. R., Lietman, P. S. Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. Am. J. Med. 77 (1984) 657–662.