Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Nature - Tập 404 Số 6779 - Trang 787-790 - 2000
Takeshi Nishikawa1, Diane Edelstein2, Xue Du2, Sho‐ichi Yamagishi2, Takeshi Matsumura2, Yasufumi Kaneda3, Mark A. Yorek4, David A. Beebe5, Peter J. Oates5, Hans‐Peter Hammes6, Ida Giardino2, Michael Brownlee2
1Albert Einstein College of Medicine, Diabetes Research Centre, Bronx, New York 10461, USA.
2Albert Einstein College of Medicine, Diabetes Research Centre, Bronx, USA
3Division of Gene Therapy Science, Osaka University Medical School, Suita, Japan
4Department of Internal Medicine, University of Iowa, Iowa City, USA
5Department of Metabolic Diseases Central Research Division, Pfizer Inc., Groton, USA
6Justus-Liebig University III Medical Department, Giessen, Germany

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