Normal tissue complication probability (NTCP) models for modern radiation therapy

Seminars in Oncology - Tập 46 Số 3 - Trang 210-218 - 2019
Giuseppe Palma1, Serena Monti1, Manuel Conson2, Roberto Pacelli2, Laura Cella1
1National Research Council, Institute of Biostructures and Bioimaging, Napoli, Italy
2Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

Yorke, 2001, Modeling the effects of inhomogeneous dose distributions in normal tissues, Semin Radiat Oncol, 11, 197, 10.1053/srao.2001.23478

Tommasino, 2017, Increasing the power of tumour control and normal tissue complication probability modelling in radiotherapy: recent trends and current issues, Transl Cancer Res, 6, S807, 10.21037/tcr.2017.06.03

Deasy, 2014, Advancing our quantitative understanding of radiotherapy normal tissue morbidity, Acta Oncol, 53, 577, 10.3109/0284186X.2014.907055

Bentzen, 2010, Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues, Int J Radiat Oncol Biol Phys, 76, S3, 10.1016/j.ijrobp.2009.09.040

Lyman, 1985, Complication probability as assessed from dose-volume histograms, Radiat Res Suppl, 8, S13, 10.2307/3583506

Kutcher, 1989, Calculation of complication probability factors for non-uniform normal tissue irradiation: the effective volume method, Int J Radiat Oncol Biol Phys, 16, 1623, 10.1016/0360-3016(89)90972-3

Kutcher, 1991, Histogram reduction method for calculating complication probabilities for three-dimensional treatment planning evaluations, Int J Radiat Oncol Biol Phys, 21, 137, 10.1016/0360-3016(91)90173-2

Burman, 1991, Fitting of normal tissue tolerance data to an analytic function, Int J Radiat Oncol Biol Phys, 21, 123, 10.1016/0360-3016(91)90172-Z

Kallman, 1992, Tumour and normal tissue responses to fractionated non-uniform dose delivery, Int J Radiat Biol, 62, 249, 10.1080/09553009214552071

Gagliardi, 1996, Long-term cardiac mortality after radiotherapy of breast cancer–application of the relative seriality model, Br J Radiol, 69, 839, 10.1259/0007-1285-69-825-839

Gagliardi, 2000, Radiation pneumonitis after breast cancer irradiation: analysis of the complication probability using the relative seriality model, Int J Radiat Oncol Biol Phys, 46, 373, 10.1016/S0360-3016(99)00420-4

Rancati, 2004, Fitting late rectal bleeding data using different NTCP models: results from an Italian multi-centric study (AIROPROS0101), Radiother Oncol, 73, 21, 10.1016/j.radonc.2004.08.013

Semenenko, 2008, Lyman-Kutcher-Burman NTCP model parameters for radiation pneumonitis and xerostomia based on combined analysis of published clinical data, Phys Med Biol, 53, 737, 10.1088/0031-9155/53/3/014

Gulliford, 2012, Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise, Radiother Oncol, 102, 347, 10.1016/j.radonc.2011.10.022

Miah, 2013, Dose-response analysis of parotid gland function: what is the best measure of xerostomia?, Radiother Oncol, 106, 341, 10.1016/j.radonc.2013.03.009

Cella, 2014, Complication probability models for radiation-induced heart valvular dysfunction: do heart-lung interactions play a role?, PLoS One, 9, 10.1371/journal.pone.0111753

D'Avino, 2015, Prediction of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer, Radiat Oncol, 10, 80, 10.1186/s13014-015-0389-5

El Naqa, 2006, Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors, Int J Radiat Oncol Biol Phys, 64, 1275, 10.1016/j.ijrobp.2005.11.022

Rancati, 2011, Inclusion of clinical risk factors into NTCP modelling of late rectal toxicity after high dose radiotherapy for prostate cancer, Radiother Oncol, 100, 124, 10.1016/j.radonc.2011.06.032

Defraene, 2012, The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer, Int J Radiat Oncol Biol Phys, 82, 1233, 10.1016/j.ijrobp.2011.03.056

Tucker, 2008, Analysis of radiation pneumonitis risk using a generalized Lyman model, Int J Radiat Oncol Biol Phys, 72, 568, 10.1016/j.ijrobp.2008.04.053

van der Schaaf, 2015, Embracing phenomenological approaches to normal tissue complication probability modeling: a question of method, Int J Radiat Oncol Biol Phys, 91, 468, 10.1016/j.ijrobp.2014.10.017

Dobson, 2018, 376

Huang, 2011, Heart irradiation as a risk factor for radiation pneumonitis, Acta Oncol, 50, 51, 10.3109/0284186X.2010.521192

Cella, 2012, Development of multivariate NTCP models for radiation-induced hypothyroidism: a comparative analysis, Radiat Oncol, 7, 224, 10.1186/1748-717X-7-224

Cella, 2013, Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer, Radiat Oncol, 8, 221, 10.1186/1748-717X-8-221

Cella, 2013, Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors, Int J Radiat Oncol Biol Phys, 87, 304, 10.1016/j.ijrobp.2013.05.049

Cella, 2015, Modeling the risk of radiation-induced lung fibrosis: irradiated heart tissue is as important as irradiated lung, Radiother Oncol, 117, 36, 10.1016/j.radonc.2015.07.051

Coates, 2015, Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer, Radiother Oncol, 115, 107, 10.1016/j.radonc.2015.03.005

Wijsman, 2015, Multivariable normal-tissue complication modeling of acute esophageal toxicity in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-)radiotherapy, Radiother Oncol, 117, 49, 10.1016/j.radonc.2015.08.010

Cozzarini, 2017, Patient-reported urinary incontinence after radiotherapy for prostate cancer: quantifying the dose-effect, Radiother Oncol, 125, 101, 10.1016/j.radonc.2017.07.029

Luxton, 2004, Dosimetry and radiobiologic model comparison of IMRT and 3D conformal radiotherapy in treatment of carcinoma of the prostate, Int J Radiat Oncol Biol Phys, 59, 267, 10.1016/j.ijrobp.2004.01.024

Michalski, 2010, Radiation dose-volume effects in radiation-induced rectal injury, Int J Radiat Oncol Biol Phys, 76, S123, 10.1016/j.ijrobp.2009.03.078

Beetz, 2012, External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy, Radiother Oncol, 105, 94, 10.1016/j.radonc.2011.11.006

Troeller, 2015, Comparison and limitations of DVH-based NTCP models derived from 3D-CRT and IMRT data for prediction of gastrointestinal toxicities in prostate cancer patients by using propensity score matched pair analysis, Int J Radiat Oncol Biol Phys, 91, 435, 10.1016/j.ijrobp.2014.09.046

Robinson, 2015, Modeling early haematologic adverse events in conformal and intensity-modulated pelvic radiotherapy in anal cancer, Radiother Oncol, 117, 246, 10.1016/j.radonc.2015.09.009

Teoh, 2011, Volumetric modulated arc therapy: a review of current literature and clinical use in practice, Br J Radiol, 84, 967, 10.1259/bjr/22373346

Cella, 2001, New techniques in hadrontherapy: intensity modulated proton beams, Phys Med, 17, 100

Bortfeld, 2017, Three ways to make proton therapy affordable, Nature, 549, 451, 10.1038/549451a

Durante, 2017, Charged-particle therapy in cancer: clinical uses and future perspectives, Nat Rev Clin Oncol, 14, 483, 10.1038/nrclinonc.2017.30

Laine, 2015, The role of hypofractionated radiation therapy with photons, protons, and heavy ions for treating extracranial lesions, Front Oncol, 5, 302

Astrahan, 2008, Some implications of linear-quadratic-linear radiation dose-response with regard to hypofractionation, Med Phys, 35, 4161, 10.1118/1.2969065

Guckenberger, 2014, Definition of stereotactic body radiotherapy: principles and practice for the treatment of stage I non-small cell lung cancer, Strahlenther Onkol, 190, 26, 10.1007/s00066-013-0450-y

D'Andrea, 2017, Radiobiological optimization in lung stereotactic body radiation therapy: are we ready to apply radiobiological models?, Front Oncol, 7, 321, 10.3389/fonc.2017.00321

Kasperts, 2005, A review on re-irradiation for recurrent and second primary head and neck cancer, Oral Oncol, 41, 225, 10.1016/j.oraloncology.2004.07.006

Milano, 2018, Review of thoracic reirradiation with stereotactic body radiation therapy: a focus on toxicity risks, Pract Radiat Oncol, 8, 251, 10.1016/j.prro.2018.01.008

Pinnix, 2018, Predictors of hypothyroidism in Hodgkin lymphoma survivors after intensity modulated versus 3-dimensional radiation therapy, Int J Radiat Oncol Biol Phys, 101, 530, 10.1016/j.ijrobp.2018.03.003

Marks, 2010, Radiation dose-volume effects in the lung, Int J Radiat Oncol Biol Phys, 76, S70, 10.1016/j.ijrobp.2009.06.091

Tucker, 2013, Predicting pneumonitis risk: a dosimetric alternative to mean lung dose, Int J Radiat Oncol Biol Phys, 85, 522, 10.1016/j.ijrobp.2012.03.052

Tucker, 2019, Validation of effective dose as a better predictor of radiation pneumonitis risk than mean lung dose: secondary analysis of a randomized trial, Int J Radiat Oncol Biol Phys, 103, 403, 10.1016/j.ijrobp.2018.09.029

Pinnix, 2015, Predictors of radiation pneumonitis in patients receiving intensity modulated radiation therapy for Hodgkin and non-Hodgkin lymphoma, Int J Radiat Oncol Biol Phys, 92, 175, 10.1016/j.ijrobp.2015.02.010

Cella, 2014, Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: predictors of radiation-induced lung injury, Acta Oncol, 53, 613, 10.3109/0284186X.2013.850739

Chun, 2017, Impact of intensity-modulated radiation therapy technique for locally advanced non-small-cell lung cancer: a secondary analysis of the NRG oncology RTOG 0617 randomized clinical trial, J Clin Oncol, 35, 56, 10.1200/JCO.2016.69.1378

Liao, 2018, Bayesian adaptive randomization trial of passive scattering proton therapy and intensity-modulated photon radiotherapy for locally advanced non-small-cell lung cancer, J Clin Oncol, 36, 1813, 10.1200/JCO.2017.74.0720

Durante, 2010, Charged particles in radiation oncology, Nat Rev Clin Oncol, 7, 37, 10.1038/nrclinonc.2009.183

Tessonnier, 2017, Dosimetric verification in water of a Monte Carlo treatment planning tool for proton, helium, carbon and oxygen ion beams at the Heidelberg Ion Beam Therapy Center, Phys Med Biol, 62, 6579, 10.1088/1361-6560/aa7be4

2008

Durante, 2018, Heavy charged particles: does improved precision and higher biological effectiveness translate to better outcome in patients?, Semin Radiat Oncol, 28, 160, 10.1016/j.semradonc.2017.11.004

Paganetti, 2015, Relating proton treatments to photon treatments via the relative biological effectiveness-should we revise current clinical practice?, Int J Radiat Oncol Biol Phys, 91, 892, 10.1016/j.ijrobp.2014.11.021

2007

Lambrecht, 2018, Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus, Radiother Oncol, 128, 26, 10.1016/j.radonc.2018.05.001

Kramer, 2000, Treatment planning for heavy-ion radiotherapy: calculation and optimization of biologically effective dose, Phys Med Biol, 45, 3319, 10.1088/0031-9155/45/11/314

Blanchard, 2016, Toward a model-based patient selection strategy for proton therapy: external validation of photon-derived normal tissue complication probability models in a head and neck proton therapy cohort, Radiother Oncol, 121, 381, 10.1016/j.radonc.2016.08.022

Langendijk, 2018, Clinical trial strategies to compare protons with photons, Semin Radiat Oncol, 28, 79, 10.1016/j.semradonc.2017.11.008

Prayongrat, 2018, Present developments in reaching an international consensus for a model-based approach to particle beam therapy, J Radiat Res, 59, i72, 10.1093/jrr/rry008

Mee, 2018, Mathematical modelling for patient selection in proton therapy, Clin Oncol (R Coll Radiol), 30, 299, 10.1016/j.clon.2018.01.007

Pehlivan, 2012, Temporal lobe toxicity analysis after proton radiation therapy for skull base tumors, Int J Radiat Oncol Biol Phys, 83, 1432, 10.1016/j.ijrobp.2011.10.042

McDonald, 2015, Dose-volume relationships associated with temporal lobe radiation necrosis after skull base proton beam therapy, Int J Radiat Oncol Biol Phys, 91, 261, 10.1016/j.ijrobp.2014.10.011

Stieb, 2018, Long-term clinical safety of high-dose proton radiation therapy delivered with pencil beam scanning technique for extracranial chordomas and chondrosarcomas in adult patients: clinical evidence of spinal cord tolerance, Int J Radiat Oncol Biol Phys, 100, 218, 10.1016/j.ijrobp.2017.08.037

Dutz, 2019, Development and validation of NTCP models for acute side-effects resulting from proton beam therapy of brain tumours, Radiother Oncol, 130, 164, 10.1016/j.radonc.2018.06.036

Taffelli, 2018, Modeling the risk of radiation induced alopecia in brain tumor patients treated with active beam proton therapy, Int J Radiat Oncol Biol Phys, 102, S211, 10.1016/j.ijrobp.2018.07.124

Tommasino, 2017, Model-based approach for quantitative estimates of skin, heart, and lung toxicity risk for left-side photon and proton irradiation after breast-conserving surgery, Acta Oncol, 56, 730, 10.1080/0284186X.2017.1299218

Fellin, 2019, Potential skin morbidity reduction with intensity-modulated proton therapy for breast cancer with nodal involvement, Acta Oncol, 58, 1, 10.1080/0284186X.2019.1591638

Min, 2014, Evaluation of permanent alopecia in pediatric medulloblastoma patients treated with proton radiation, Radiat Oncol, 9, 220, 10.1186/s13014-014-0220-8

Pastore, 2016, Dose-surface analysis for prediction of severe acute radio-induced skin toxicity in breast cancer patients, Acta Oncol, 55, 466, 10.3109/0284186X.2015.1110253

Palma, 2019, A new formalism of Dose Surface Histograms for robust modeling of skin toxicity in radiation therapy, Phys Med, 59, 75, 10.1016/j.ejmp.2019.02.005

Yanagi, 2010, Dose-volume histogram and dose-surface histogram analysis for skin reactions to carbon ion radiotherapy for bone and soft tissue sarcoma, Radiother Oncol, 95, 60, 10.1016/j.radonc.2009.08.041

Fukahori, 2016, Estimation of late rectal normal tissue complication probability parameters in carbon ion therapy for prostate cancer, Radiother Oncol, 118, 136, 10.1016/j.radonc.2015.11.023

Okonogi, 2018, Dose constraints in the rectum and bladder following carbon-ion radiotherapy for uterus carcinoma: a retrospective pooled analysis, Radiat Oncol, 13, 119, 10.1186/s13014-018-1061-7

Nahum, 2015, The radiobiology of hypofractionation, Clin Oncol (R Coll Radiol), 27, 260, 10.1016/j.clon.2015.02.001

Douglas, 1976, The effect of multiple small doses of x rays on skin reactions in the mouse and a basic interpretation, Radiat Res, 66, 401, 10.2307/3574407

Fowler, 1989, The linear-quadratic formula and progress in fractionated radiotherapy, Br J Radiol, 62, 679, 10.1259/0007-1285-62-740-679

Wang, 2010, A generalized linear-quadratic model for radiosurgery, stereotactic body radiation therapy, and high-dose rate brachytherapy, Sci Transl Med, 2, 39ra48, 10.1126/scitranslmed.3000864

Park, 2008, Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy, Int J Radiat Oncol Biol Phys, 70, 847, 10.1016/j.ijrobp.2007.10.059

Hoffmann, 2013, Fractionation in normal tissues: the (alpha/beta)EFF concept can account for dose heterogeneity and volume effects, Phys Med Biol, 58, 6897, 10.1088/0031-9155/58/19/6897

Ricardi, 2009, Dosimetric predictors of radiation-induced lung injury in stereotactic body radiation therapy, Acta Oncol, 48, 571, 10.1080/02841860802520821

Borst, 2010, Radiation pneumonitis after hypofractionated radiotherapy: evaluation of the LQ(L) model and different dose parameters, Int J Radiat Oncol Biol Phys, 77, 1596, 10.1016/j.ijrobp.2009.10.015

Tanguturi, 2017, Gallbladder toxicity and high-dose ablative-intent radiation for liver tumors: should we constrain the dose?, Pract Radiat Oncol, 7, e323, 10.1016/j.prro.2017.02.001

Jones, 2001, The role of biologically effective dose (BED) in clinical oncology, Clin Oncol, 13, 71

Woolley, 2018, Changes in the retreatment radiation tolerance of the spinal cord with time after the initial treatment, Int J Radiat Biol, 94, 515, 10.1080/09553002.2018.1430911

Nieder, 2000, Tissue tolerance to reirradiation, Semin Radiat Oncol, 10, 200, 10.1053/srao.2000.6593

Nieder, 2016, 1

Boman, 2017, Importance of deformable image registration and biological dose summation in planning of radiotherapy retreatments, Med Dosim, 42, 296, 10.1016/j.meddos.2017.06.006

McVicar, 2018, Re-irradiation volumetric modulated arc therapy optimization based on cumulative biologically effective dose objectives, J Appl Clin Med Phys, 19, 341, 10.1002/acm2.12481

Niemierko, 1997, Reporting and analyzing dose distributions: a concept of equivalent uniform dose, Med Phys, 24, 103, 10.1118/1.598063

Krauze, 2017, Re-irradiation for recurrent glioma- the NCI experience in tumor control, OAR toxicity and proposal of a novel prognostic scoring system, Radiat Oncol, 12, 191, 10.1186/s13014-017-0930-9

El Naqa, 2018, Radiation therapy outcomes models in the era of radiomics and radiogenomics: uncertainties and validation, Int J Radiat Oncol Biol Phys, 102, 1070, 10.1016/j.ijrobp.2018.08.022

Scheenstra, 2013, Local dose-effect relations for lung perfusion post stereotactic body radiotherapy, Radiother Oncol, 107, 398, 10.1016/j.radonc.2013.04.003

Defraene, 2015, CT characteristics allow identification of patient-specific susceptibility for radiation-induced lung damage, Radiother Oncol, 117, 29, 10.1016/j.radonc.2015.07.033

Defraene, 2017, Regional variability in radiation-induced lung damage can be predicted by baseline CT numbers, Radiother Oncol, 122, 300, 10.1016/j.radonc.2016.11.021

Avanzo, 2017, Voxel-by-voxel correlation between radiologically radiation-induced lung injury and dose after image-guided, intensity modulated radiotherapy for lung tumors, Phys Med, 42, 150, 10.1016/j.ejmp.2017.09.127

van den Bogaard, 2019, Cardiac function after radiotherapy for breast cancer, Int J Radiat Oncol Biol Phys, 104, 392, 10.1016/j.ijrobp.2019.02.003

Peeler, 2016, Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma, Radiother Oncol, 121, 395, 10.1016/j.radonc.2016.11.001

Connor, 2017, Regional susceptibility to dose-dependent white matter damage after brain radiotherapy, Radiother Oncol, 123, 209, 10.1016/j.radonc.2017.04.006

Jeraj, 2010, Imaging for assessment of radiation-induced normal tissue effects, Int J Radiat Oncol Biol Phys, 76, S140, 10.1016/j.ijrobp.2009.08.077

Palma, 2015, A novel multiparametric approach to 3D quantitative MRI of the brain, PLoS One, 10, 10.1371/journal.pone.0134963

Monti, 2017, RESUME: turning an SWI acquisition into a fast qMRI protocol, PLoS One, 12, 10.1371/journal.pone.0189933

Partridge, 2010, Imaging of normal lung, liver and parotid gland function for radiotherapy, Acta Oncol, 49, 997, 10.3109/0284186X.2010.504735

Monti, 2015, A multiparametric and multiscale approach to automated segmentation of brain veins, Conf Proc IEEE Eng Med Biol Soc, 2015, 3041

Monti, 2017, MAVEN: an algorithm for multi-parametric automated segmentation of brain veins from gradient echo acquisitions, IEEE Trans Med Imaging, 36, 1054, 10.1109/TMI.2016.2645286

van Luijk, 2015, Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer, Sci Transl Med, 7, 305ra147, 10.1126/scitranslmed.aac4441

Jiang, 2018, Machine learning methods uncover radiomorphologic dose patterns in salivary glands that predict xerostomia in patients with head and neck cancer, Adv Radiat Oncol, 4, 401, 10.1016/j.adro.2018.11.008

Seppenwoolde, 2004, Regional differences in lung radiosensitivity after radiotherapy for non–small-cell lung cancer, Int J Radiat Oncol Biol Phys, 60, 748, 10.1016/j.ijrobp.2004.04.037

Palma, 2016, A voxel-based approach to explore local dose differences associated with radiation-induced lung damage, Int J Radiat Oncol Biol Phys, 96, 127, 10.1016/j.ijrobp.2016.04.033

Monti, 2018, Inter-patient image registration algorithms to disentangle regional dose bioeffects, Sci Rep, 8, 4915, 10.1038/s41598-018-23327-0

Palma, 2019, Spatial dose patterns associated with radiation pneumonitis in a randomized trial comparing intensity-modulated radiation therapy with passive scattering proton therapy for locally advanced non-small cell lung cancer, Int J Radiat Oncol Biol Phys, 104, 1124, 10.1016/j.ijrobp.2019.02.039

Palorini, 2016, First application of a pixel-wise analysis on bladder dose-surface maps in prostate cancer radiotherapy, Radiother Oncol, 119, 123, 10.1016/j.radonc.2016.02.025

Yahya, 2017, Modeling urinary dysfunction after external beam radiation therapy of the prostate using bladder dose-surface maps: evidence of spatially variable response of the bladder surface, Int J Radiat Oncol Biol Phys, 97, 420, 10.1016/j.ijrobp.2016.10.024

Acosta, 2013, Voxel-based population analysis for correlating local dose and rectal toxicity in prostate cancer radiotherapy, Phys Med Biol, 58, 2581, 10.1088/0031-9155/58/8/2581

Drean, 2016, Interindividual registration and dose mapping for voxelwise population analysis of rectal toxicity in prostate cancer radiotherapy, Med Phys, 43, 2721, 10.1118/1.4948501

Drean, 2016, Identification of a rectal subregion highly predictive of rectal bleeding in prostate cancer IMRT, Radiother Oncol, 119, 388, 10.1016/j.radonc.2016.04.023

Monti, 2017, Voxel-based analysis unveils regional dose differences associated with radiation-induced morbidity in head and neck cancer patients, Sci Rep, 7, 7220, 10.1038/s41598-017-07586-x

Beasley, 2018, Image-based data mining to probe dosimetric correlates of radiation-induced trismus, Int J Radiat Oncol Biol Phys, 10.1016/j.ijrobp.2018.05.054

Rutkowska, 2010, Mechanistic simulation of normal-tissue damage in radiotherapy–implications for dose-volume analyses, Phys Med Biol, 55, 2121, 10.1088/0031-9155/55/8/001

Palma, 2019, PACE: a probabilistic atlas for normal tissue complication estimation in radiation oncology, Front Oncol, 9, 130, 10.3389/fonc.2019.00130