Nuốt Bình Thường và Chụp Cộng Hưởng Từ Chức Năng: Một Đánh Giá Hệ Thống

Dysphagia - Tập 22 - Trang 266-275 - 2007
Ianessa A. Humbert1,2, JoAnne Robbins1
1William S. Middleton Memorial Veterans Hospital, Department of Medicine, University of Wisconsin-Madison, Madison, USA
2Department of Medicine, University of Wisconsin-Madison, Madison, USA

Tóm tắt

Những điều chưa biết về sinh lý thần kinh của quá trình nuốt bình thường và rối loạn đã kích thích nhiều câu hỏi nghiên cứu thú vị và quan trọng. Trước đây, các câu hỏi này đã được trả lời bằng các nghiên cứu lâm sàng và trên động vật. Tuy nhiên, các tiến bộ công nghệ gần đây đã đưa các kỹ thuật chụp ảnh não như chụp cộng hưởng từ chức năng (fMRI) lên hàng đầu trong nghiên cứu sinh lý thần kinh của quá trình nuốt. Đánh giá hệ thống này đã tóm tắt các phương pháp và kết quả của các nghiên cứu về sinh lý thần kinh của quá trình nuốt ở người lớn khỏe mạnh sử dụng fMRI. Một tìm kiếm điện tử và thủ công toàn diện cho các nghiên cứu gốc đã được thực hiện, bao gồm ít giới hạn tìm kiếm nhằm thu được số lượng tối đa các nghiên cứu có liên quan. Các tham gia, thiết kế nghiên cứu, nhiệm vụ và quá trình thu nhận hình ảnh não đã được xem xét và kết quả cho thấy rằng các khu vực vận động chính và cảm giác hoạt động thường xuyên nhất ở các người tham gia lành mạnh trong tất cả các nghiên cứu có liên quan. Các khu vực hoạt động phổ biến khác bao gồm vỏ não cingulate trước và vỏ não insula. Các giới hạn của bản đánh giá và các hướng đi tương lai được đề xuất cũng được thảo luận.

Từ khóa

#nuốt bình thường #sinh lý thần kinh #fMRI #hoạt động não #nghiên cứu lâm sàng.

Tài liệu tham khảo

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