Normal Structure, Function, and Histology of the Spleen
Tóm tắt
The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. These functions are carried out by the 2 main compartments of the spleen, the white pulp (including the marginal zone) and the red pulp, which are vastly different in their architecture, vascular organization, and cellular composition. The morphology of these compartments is described and, to a lesser extent, their functions are discussed. The variation between species and effects of aging and genetics on splenic morphology are also discussed.
Từ khóa
Tài liệu tham khảo
Custer RP, 1985, Am J Pathol, 120, 464
Hanes MA, 2005, The Laboratory Rat, 733
HoganEsch H, 2001, Pathobiology of the Aging Dog, 1, 127
Losco P, 1992, Pathobiology of the Aging Rat, 1, 75
Nicander L, 1993, Textbook of Veterinary Histology, 120
Schmidt EE, 1993, Scanning Microsc, 7, 613
Stefanski SA, 1990, Pathology of the Fisher Rat, 369
Van Rees EP, 1996, Pathobiology of the Aging Mouse, 1, 173
Ward JM, 1999, Pathology of the Mouse, 333