Non-occupational risk factors for cancer of the lower urinary tract in Germany
Tóm tắt
In a hospital-based case–control study conducted between 1989 and 1992 in Hessen (West-Germany) 300 cases (239 male and 61 female) of histologically confirmed cancer of the lower urinary tract (LUT) were individually matched to controls from the same hospitals with respect to sex, age and area of residence. Smoking of cigarettes was associated with an elevated risk of 2.80 in males (95% confidence interval (CI): 1.65–4.76) and 5.33 (95% CI: 1.55–18.33) in females, as compared with non-smokers. Variables like daily amount of smoked cigarettes, duration of smoking, age at beginning of cigarette smoking and time since smoking cessation showed a clear dose- and time–response relationship in males, but not in females. Elevated risks were observed for higher consumption of coffee, beer and wine, but – especially for the consumption of coffee – were drastically reduced after adjustment for smoking. A weak association was found between the daily fluid intake and bladder cancer in males. Among females a significantly decreased odds ratio (OR) of 0.34 (95% CI: 0.11–0.99) was found for a daily fluid intake of more than two liters. Protective effects and risk reductions of approximately 50% were found for the regular intake of raw carrots, kale, salads and fruits. The findings of this investigation support an association between lifestyle factors and cancer of the lower urinary tract.
Tài liệu tham khảo
Tomatis L, ed. Cancer: Causes, occurence and control (IARC Scientific Publications No 100). Lyon: International Agency for Research on Cancer, 1990.
Doll R, Peto R. The causes of cancer. Quantitative estimates of avoidable risks of cancer in the United States today. Oxford: Oxford University Press, 1981.
Vineis P, Simonato L. Proportion of lung and bladder cancers in males resulting from occupation: A systematic approach. Arch Environ Health 1991; 46: 6–15.
Claude J, Kunze E, Frentzel-Beyme R, Paczkowski K, Schneider J, Schubert H. Life style and occupational risk factors in cancer of the lower urinary tract. Am J Epidemiol 1986; 124: 578–589.
Kunze E, Chang-Claude J, Frentzel-Beyme R. Life style and occupational risk factors for bladder cancer in Germany. Cancer 1992; 69: 1776–1790.
Jöckel K-H, Ahrens W, Jahn I, Pohlabeln H, Bolm-Audorff U. Occupational risk factors for lung cancer: A case-control study in West-Germany. Int J Epidemiol 1998; 27: 549–560.
SAS Institute Inc., SAS/STAT Software: Changes and enhancements through Release 6.11. Cary, NC: SAS Institute Inc., 1996.
Donato F, Boffetta P, Fazioli R, et al. Bladder cancer, tobacco smoking, coffee and alcohol drinking in Brescia, northern Italy. Eur J Epidemiol 1997; 13: 795–800.
Nomura A, Kolonel LN, Yoshizawa CN. Smoking, alcohol, occupation, and hair dye use in cancer of the lower urinary tract. Am J Epidemiol 1989; 130: 1159–1163.
Hours M, Dananche B, Fevotte J, et al. Bladder cancer and occupational exposures. Scan J Work Environ Health 1994; 20: 322–330.
Howe GR, Burch JD, Miller AB, et al. Tobacco use, occupation, coffee, various nutrients, and bladder cancer. J Natl Cancer Inst 1980; 64: 701–713.
Morrison AS, Buring JE, Verhoek WG, et al. Coffee drinking and cancer of the lower urinary tract. J Natl Cancer Inst 1982; 68: 91–94.
Bedwani R, el-Khwsky F, Renganathan E, Braga C, Abu Seif HH, Abul Azm T, Zaki A, Franceschi S, Boffetta P, La Vecchia C. Epidemiology of bladder cancer in Alexandria, Egypt: Tobacco smoking. Int J Cancer 1997; 73: 64–67.
D' Avanzo B, Negri E, La Vecchia C, Gramenzi A, Bianchi C, Franceschi S, Boyle P. Cigarette smoking and bladder cancer. Eur J Cancer 1990; 26: 714–718.
Vineis P. Black (air-cured) and blond (flue-cured) tobacco and cancer risk I: Bladder cancer. Eur J Cancer 1991; 27: 1491–1493.
Momas I, Daurès J-P, Festy B, Bontoux J, Grémy F. Relative importance of risk factors in bladder carcinogenesis: Some new results about Mediterranean habits. Cancer Causes Control 1994; 5: 326–332.
Slattery ML, Schumacher MC, West DW, Robinson LM. Smoking and bladder cancer — the modifying effect of cigarettes on other factors. Cancer 1988; 61: 402–408.
Cole PH, Monson RR, Haning H, Friedell GH. Smoking and cancer of the lower urinary tract. N Engl J Med 1971; 284: 129–134.
Reza Najem GR, Louria DB, Seebode JJ, et al. Life time occupation, smoking, caffeine, saccharine, hairdyes and bladder carcinogenes. Int J Epidemiol 1982; 11: 212–217.
Burck, JD, Rohan TE, Howe GR, et al. Risk of bladder cancer by source and type of tobacco exposure: A case-control study. Int J Cancer 1989; 44: 622–628.
Hartge P, Hoover R, Kantor A. Bladder cancer risk and pipes, cigars and smokeless tobacco. Cancer 1985; 55: 901–906.
Cole P. Coffee-drinking and cancer of the lower urinary tract. Lancet 1971; 26: 1335–1337.
Risch HA, Burch JD, Miller AB, Hill GB, Steele R, Howe GR. Dietary factors and the incidence of cancer of the urinary bladder. Am J Epidemiol 1988; 127: 1179–1191.
Marrett LD, Walter SD, Meigs JW. Coffee drinking and bladder cancer in Connecticut. Am J Epidemiol 1983; 117: 113–127.
Jensen OM, Wahrendorf J, Knudsen JB, Sørensen BL. The Copenhagen case-control study of bladder cancer. II. Effect of coffee and other beverages. Int J Cancer 1986; 37: 651–657.
Barbone F, Franceschi S, Talamini R, Bidoli E, La Vecchia C. Occupation and bladder cancer in Pordenone (North-East Italy): A case-control study. Int J Epidemiol 1994; 23: 58–65.
Hartge P, Hoover R, West DW, Lyon JL. Coffe drinking and risk of bladder cancer. J Natl Cancer Inst 1983; 70: 1021–1026.
Viscoli CM, Lachs MS, Horwitz RI. Bladder cancer and coffee drinking: A summary of case-control research. The Lancet 1993; 341: 1432–1437.
Mills PK, Beeson WL, Phillips RL, Fraser GE. Bladder cancer in a low risk population: Results from the Adventist Health Study. Am J Epidemiol 1991; 133: 230–239.
Thomas DB, Uhl CN, Hartge P. Bladder cancer and alcoholic beverage consumption. Am J Epidemiol 1983; 118: 720–727.
La Vecchia C, Negri E, Decarli A, D' Avonzo B, Liberati C, Franceschi S. Dietary factors in the risk of bladder cancer. Nutr Cancer 1989; 12: 93–101.
Mettlin C, Graham, S. Dietary risk factors in human bladder cancer. Am J Epidemiol 1979; 110: 255–263.
Mettlin C, Graham S, Swanson M. Vitamin A and lung cancer. J Natl Cancer Inst 1979; 62: 1435–1438.
Riboli E, Gonzáles CA, López-Abente G, Errezola M, Izarzugaza I, Escolar A, et al. Diet and bladder cancer in Spain: A case-control study. Int J Cancer 1991, 49: 214–219.
Steineck G, Hagman U, Gerhardsson M, Norell SE. Vitamin A supplements, fried foods, fat and urothelial cancer. A case-referent study in Stockholm in 1985–87. Int J Cancer 1990; 45: 1006–1011.
La Vecchia C, Negri E. Nutrition and bladder cancer. Cancer causes and controls 1996; 7: 101–111.