Non-coding RNAs are promising targets for stem cell-based cancer therapy

Macfarlane, 2010, MicroRNA: biogenesis, function and role in cancer, Curr. Genomics, 11, 537, 10.2174/138920210793175895 Kung, 2013, Long noncoding RNAs: past, present, and future, Genetics, 193, 651, 10.1534/genetics.112.146704 Brosnan, 2009, The long and the short of noncoding RNAs, Curr. Opin. Cell Biol., 21, 416, 10.1016/j.ceb.2009.04.001 Huang, 2013, Noncoding RNAs in cancer and cancer stem cells, Chin. J. Cancer, 32, 582, 10.5732/cjc.013.10170 Rusek, 2015, MicroRNA modulators of epigenetic regulation, the tumor microenvironment and the immune system in lung cancer, Mol. Cancer, 14, 34, 10.1186/s12943-015-0302-8 Gloss, 2016, The specificity of long noncoding RNA expression, Biochim. Biophys. Acta, 1859, 16, 10.1016/j.bbagrm.2015.08.005 Jia, 2013, The functions of microRNAs and long non-coding RNAs in embryonic and induced pluripotent stem cells, Genom. Proteom. Bioinforma., 11, 275, 10.1016/j.gpb.2013.09.004 Huo, 2013, Pivots of pluripotency: the roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells, Biochim. Biophys. Acta, 1830, 2385, 10.1016/j.bbagen.2012.10.014 Fatica, 2014, Long non-coding RNAs: new players in cell differentiation and development, Nat. Rev. Genet., 15, 7, 10.1038/nrg3606 Schratt, 2006, A brain-specific microRNA regulates dendritic spine development, Nature, 439, 283, 10.1038/nature04367 Cordes, 2009, MicroRNA regulation of cardiovascular development, Circ. Res., 104, 724, 10.1161/CIRCRESAHA.108.192872 Magee, 2012, Cancer stem cells: impact, heterogeneity, and uncertainty, Cancer Cell, 21, 283, 10.1016/j.ccr.2012.03.003 Barker, 2010, Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells, Gastroenterology, 138, 1681, 10.1053/j.gastro.2010.03.002 Mak, 2014, CD133-targeted niche-dependent therapy in cancer: a multipronged approach, Am. J. Pathol., 184, 1256, 10.1016/j.ajpath.2014.01.008 Neveu, 2010, MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states, Cell Stem Cell, 7, 671, 10.1016/j.stem.2010.11.012 Chin, 2009, Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures, Cell Stem Cell, 5, 111, 10.1016/j.stem.2009.06.008 Anokye-Danso, 2011, Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency, Cell Stem Cell, 8, 376, 10.1016/j.stem.2011.03.001 Wang, 2012, Quantitative functions of Argonaute proteins in mammalian development, Genes Dev., 26, 693, 10.1101/gad.182758.111 He, 2005, A microRNA polycistron as a potential human oncogene, Nature, 435, 828, 10.1038/nature03552 Choi, 2011, miR-34 miRNAs provide a barrier for somatic cell reprogramming, Nat. Cell Biol., 13, 1353, 10.1038/ncb2366 Melton, 2010, Opposing microRNA families regulate self-renewal in mouse embryonic stem cells, Nature, 463, 621, 10.1038/nature08725 Chang, 2009, Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation, Proc. Natl. Acad. Sci. U. S. A., 106, 3384, 10.1073/pnas.0808300106 Pourrajab, 2014, MicroRNA-based system in stem cell reprogramming; differentiation/dedifferentiation, Int. J. Biochem. Cell Biol., 55, 318, 10.1016/j.biocel.2014.08.008 Subramanyam, 2011, Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells, Nat. Biotechnol., 29, 443, 10.1038/nbt.1862 Samavarchi-Tehrani, 2010, Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming, Cell Stem Cell, 7, 64, 10.1016/j.stem.2010.04.015 Li, 2011, Small RNA-mediated regulation of iPS cell generation, Embo J., 30, 823, 10.1038/emboj.2011.2 Lu, 2012, MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs, PLoS One, 7, e40938, 10.1371/journal.pone.0040938 Kuo, 2012, A novel role of miR-302/367 in reprogramming, Biochem. Biophys. Res. Commun., 417, 11, 10.1016/j.bbrc.2011.11.058 Dinger, 2008, Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation, Genome Res., 18, 1433, 10.1101/gr.078378.108 Guttman, 2011, lincRNAs act in the circuitry controlling pluripotency and differentiation, Nature, 477, 295, 10.1038/nature10398 Li, 2015, Large noncoding RNAs are promising regulators in embryonic stem cells, J. Genet. Genomics, 42, 99, 10.1016/j.jgg.2015.02.002 Sheik Mohamed, 2010, Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells, Rna, 16, 324, 10.1261/rna.1441510 Loewer, 2010, Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells, Nat. Genet., 42, 1113, 10.1038/ng.710 Zhao, 2008, Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome, Science, 322, 750, 10.1126/science.1163045 Ng, 2012, Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors, Embo J., 31, 522, 10.1038/emboj.2011.459 Calin, 2007, Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas, Cancer Cell, 12, 215, 10.1016/j.ccr.2007.07.027 Goto, 2016, The transcribed-ultraconserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation, Oncogene, 35, 3598, 10.1038/onc.2015.445 Shimono, 2009, Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells, Cell, 138, 592, 10.1016/j.cell.2009.07.011 McDermott, 2010, Targeting breast cancer stem cells, Mol. Oncol., 4, 404, 10.1016/j.molonc.2010.06.005 Jung, 2011, Differentially expressed microRNAs in pancreatic cancer stem cells, Pancreas, 40, 1180, 10.1097/MPA.0b013e318221b33e Ji, 2009, MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells, PLoS One, 4, e6816, 10.1371/journal.pone.0006816 Gupta, 2010, Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis, Nature, 464, 1071, 10.1038/nature08975 Cheng, 2012, piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells, Cancer Lett., 315, 12, 10.1016/j.canlet.2011.10.004 Cheng, 2011, piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells, Clin. Chim. Acta, 412, 1621, 10.1016/j.cca.2011.05.015 Frith, 2014, Concise review: new frontiers in microRNA-based tissue regeneration, Stem Cells Transl. Med., 3, 969, 10.5966/sctm.2014-0032 Hullinger, 2012, Inhibition of miR-15 protects against cardiac ischemic injury, Circ. Res., 110, 71, 10.1161/CIRCRESAHA.111.244442 van Rooij, 2012, Developing microRNA therapeutics, Circ. Res., 110, 496, 10.1161/CIRCRESAHA.111.247916 Liu, 2011, miRNA cassettes in viral vectors: problems and solutions, Biochim. Biophys. Acta, 1809, 732, 10.1016/j.bbagrm.2011.05.014 Sen, 2015, miRNA control of tissue repair and regeneration, Am. J. Pathol., 185, 2629, 10.1016/j.ajpath.2015.04.001 Santo, 2012, From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering, Nanomedicine Lond., 7, 1045, 10.2217/nnm.12.78 Stuckey, 2014, Stem cell-based therapies for cancer treatment: separating hope from hype, Nat. Rev. Cancer, 14, 683, 10.1038/nrc3798 Martinez-Quintanilla, 2013, Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors, Stem Cells, 31, 1706, 10.1002/stem.1355 Ito, 2010, Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma, Cancer Gene Ther., 17, 299, 10.1038/cgt.2009.80 Yi, 2014, Selective antitumor effect of neural stem cells expressing cytosine deaminase and interferon-beta against ductal breast cancer cells in cellular and xenograft models, Stem Cell Res., 12, 36, 10.1016/j.scr.2013.09.010 Yan, 2013, Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: a double-target therapy against non-Hodgkin's lymphoma, Mol. Pharm., 10, 142, 10.1021/mp300261e