No-Touch Disinfection Methods to Decrease Multidrug-Resistant Organism Infections: A Systematic Review and Meta-analysis

Infection Control and Hospital Epidemiology - Tập 39 Số 1 - Trang 20-31 - 2018
Alexandre R. Marra1, Marin L. Schweizer2, Michael B. Edmond1
11Office of Clinical Quality,Safety and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.
23Department of Epidemiology,University of Iowa College of Public Health,Iowa City,Iowa.

Tóm tắt

BACKGROUNDRecent studies have shown that using no-touch disinfection technologies (ie, ultraviolet light [UVL] or hydrogen peroxide vapor [HPV] systems) can limit the transmission of nosocomial pathogens and prevent healthcare-associated infections (HAIs). To investigate these findings further, we performed a systematic literature review and meta-analysis on the impact of no-touch disinfection methods to decrease HAIs.METHODSWe searched PubMed, CINAHL, CDSR, DARE and EMBASE through April 2017 for studies evaluating no-touch disinfection technology and the nosocomial infection rates forClostridium difficile, methicillin-resistantStaphylococcus aureus(MRSA), vancomycin-resistant enterococci (VRE), and other multidrug-resistant organisms (MDROs). We employed random-effect models to obtain pooled risk ratio (pRR) estimates. Heterogeneity was evaluated with I2estimation and the Cochran Q statistic. Pooled risk ratios forC. difficile, MRSA, VRE, and MDRO were assessed separately.RESULTSIn total, 20 studies were included in the final review: 13 studies using UVL systems and 7 studies using HPV systems. When the results of the UVL studies were pooled, statistically significant reduction insC. difficileinfection (CDI) (pRR, 0.64; 95% confidence interval [CI], 0.49–0.84) and VRE infection rates (pRR, 0.42; 95% CI, 0.28–0.65) were observed. No differences were found in rates of MRSA or gram-negative multidrug-resistant pathogens.CONCLUSIONSUltraviolet light no-touch disinfection technology may be effective in preventing CDI and VRE infection.Infect Control Hosp Epidemiol2018;39:20–31

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Infection Control and Hospital Epidemiology

Tập 39 Số 1

20-31

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