Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

The Lancet Oncology - Tập 16 Số 4 - Trang 375-384 - 2015
Jeffrey S. Weber1, Sandra P D'Angelo2, David R. Minor3, F. Stephen Hodi4, Ralf Gutzmer5, Bart Neyns6, Christoph Höeller7, Nikhil I. Khushalani8, Wilson H. Miller9, Christopher D. Lao10, Gerald P. Linette11, Luc Thomas12, Paul Lorigan13, Kenneth F. Grossmann14, Jessica C. Hassel15, Michele Maio16, Mario Sznol17, Paolo A. Ascierto18, Peter Mohr19, Bartosz Chmielowski20, Alan H. Bryce21, Inge Marie Svane22, Jean‐Jacques Grob23, Angela M. Krackhardt24, Christine E. Horak25, Alexandre Lambert26, Arvin Yang25, James Larkin27
1Moffitt Cancer Center, Tampa, FL, USA
2Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA
3California Pacific Center for Melanoma Research, San Francisco, CA, USA
4Dana-Farber Cancer Institute, Boston, MA, USA
5Medizinische Hochschule Hannover, Hannover, Germany
6Universitair Ziekenhuis Brussel, Brussels, Belgium
7Medical University of Vienna, Vienna, Austria
8Roswell Park Cancer Institute, Buffalo, NY, USA
9Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, QC, Canada
10University of Michigan, Ann Arbor, MI USA
11Washington University, St Louis, Mo. USA
12Centre Hospitalier Universitaire de Lyon, Lyon, France
13Christie Hospital, Manchester, UK
14Huntsman Cancer Institute, Salt Lake City, UT, USA
15German Cancer Research Centre University Hospital, Heidelberg, Germany
16Medical Oncology and Immunotherapy, University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy
17Yale Cancer Center, New Haven, CT, USA
18Istituto Nazionale Tumori, Fondazione 'G. Pascale', Naples, Italy
19Elbe Kliniken Buxtehude, Buxtehude, Germany
20Department of Medicine, University of California, Los Angeles, CA, USA
21Department of Medicine, Mayo Clinic, Scottsdale, AZ, USA
22Department of Oncology, Herlev Hospital, Copenhagen, Denmark
23Aix-Marseille University, Hopital de la Timone, Marseille, France
24Technische Universität München School of Medicine, II Medical Department, Munich, Germany
25Bristol-Myers Squibb, Princeton, NJ, USA.
26Bristol-Myers Squibb, Braine-I’Alleud, Belgium
27Royal Marsden Hospital, London, UK

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