Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

The Lancet - Tập 389 Số 10088 - Trang 2492-2502 - 2017
Anthony B. El-Khoueiry1, Bruno Sangro2, Thomas Yau3, Todd S. Crocenzi4, Masatoshi Kudo5, Chiun Hsu6, Tae‐You Kim7, Su-Pin Choo8, Jörg Trojan9, Theodore H. Welling10, Tim Meyer11, Yoon‐Koo Kang12, Winnie Yeo13, Akhil Chopra14, Jeffrey Anderson15, Christine Marie Dela Cruz15, Lixin Lang15, Jaclyn Neely15, Hao Tang15, Homa Dastani15, Ignacio Melero16,17
1USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA
2Clinica Universidad de Navarra and CIBEREHD, Pamplona, Spain
3University of Hong Kong, Hong Kong Special Administrative Region, China
4Providence Cancer Center, Portland, OR, USA
5Kindai University, Faculty of Medicine, Osaka, Japan
6National Taiwan University Hospital, Taipei, Taiwan
7Seoul National University Hospital, Seoul, South Korea
8National Cancer Center, Singapore
9Goethe University Hospital and Cancer Center, Frankfurt, Germany
10University of Michigan School of Medicine Ann Arbor MI USA
11Royal Free Hospital, London, UK
12Asan Medical Center, University of Ulsan, Seoul, South Korea
13Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
14Johns Hopkins Singapore International Medical Centre, Singapore
15Bristol-Myers Squibb, Princeton, NJ, USA.
16Biomedical Research Network in Oncology (CIBERONC), Pamplona, Spain
17Center for applied Medical Research (CIMA), Pamplona, Spain

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