Nierenbeteiligung im Rahmen von Großgefäßvaskulitiden

Der Nephrologe - Tập 7 - Trang 200-208 - 2012
A.D. Wagner1
1Klinik für Nieren- und Hochdruckerkrankungen, Medizinische Hochschule Hannover, Hannover, Deutschland

Tóm tắt

Systemische Vaskulitiden sind entzündliche Erkrankungen der Gefäße, die den ganzen Körper befallen können. Die Einteilung erfolgt nach der Größe der betroffenen Gefäße. Zu den Großgefäßvaskulitiden gehören die Riesenzellarteriitis (RZA) und die Takayasu-Arteriitis (TA). Die RZA ist durch eine granulomatöse Entzündung der mittleren und großen Arterien charakterisiert. Sie ist die häufigste systemische Vaskulitis bei Personen über dem 50. Lebensjahr. Die TA ist als eine granulomatöse Vaskulitis der Aorta und ihrer Hauptäste definiert. Sie tritt typischerweise vor dem 40. Lebensjahr auf und ist in Europa vergleichsweise selten. Bei beiden Erkrankungen können neben anderen Organen auch die Nieren in unterschiedlichem Ausmaß betroffen sein. Im vorliegenden Artikel werden beide Vaskulitiden beschrieben und die jeweiligen Therapieoptionen aufgezeigt.

Tài liệu tham khảo

Nordborg E, Bengtsson BA (1990) Epidemiology of biopsy-proven giant cell arteritis (GCA). J Intern Med 227:233–236 Reinhold-Keller E, Zeidler A, Gutfleisch J et al (2000) Giant cell arteritis is more prevalent in urban than in rural populations: results of an epidemiological study of primary systemic vasculitides in Germany. Rheumatology (Oxford) 39:1396–1402 Hunder GG, Allen GL (1978) Giant cell arteritis: a review. Bull Rheum Dis 29:980–986 Salvarani C, Gabriel SE, O’Fallon WM, Hunder GG (1995) The incidence of giant cell arteritis in Olmsted County, Minnesota: apparent fluctuations in a cyclic pattern. Ann Intern Med 123:192–194 Bengtsson BA (1991) Epidemiology of giant cell arteritis. Baillière’s Clin Rheumatol 5:379–385 Aiello PD, Trautmann JC, McPhee TJ et al (1993) Visual prognosis in giant cell arteritis. Ophthalmology 100:550–555 Evans JM, O’Fallon WM, Hunder GG (1995) Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis. A population-based study. Ann Intern Med 122:502–507 Wagner AD, Andresen J, Raum E et al (2005) Standardised work-up programme for fever of unknown origin and contribution of magnetic resonance imaging for the diagnosis of hidden systemic vasculitis. Ann Rheum Dis 64:105–110 Klein RG, Hunder GG, Stanson AW, Sheps SC (1975) Large artery involvement in giant cell (temporal) arteritis. Ann Intern Med 83:806 Moraga, Sicilia JJ, Blanco J, Ubeda I (2001) Giant cell arteritis and renal amyloidosis: report of a case. Clin Nephrol 56:402–406 Escriba A, Morales E, Albizua E et al (2000) Secondary (AA-type) amyloidosis in patients with polymyalgia rheumatica. Am J Kidney Dis 35:137–140 Altiparmak MR, Tabak F, Pamuk ON et al (2001) Giant cell arteritis and secondary amyloidosis: the natural history. Scand J Rheumatol 30:114–116 Stebbing J, Buetens O, Hellmann D, Stone J (1999) Secondary amyloidosis associated with giant cell arteritis/polymyalgia rheumatica. J Rheumatol 26:2698–2700 Strasser F, Hailemariam S, Weinreich T et al (2000) Giant cell arteritis „causing“ AA-amyloidosis with rapid renal failure. Schweiz Med Wochenschr 130:1606–1609 Estrada A, Stenzel TT, Burchette JL, Allen NB (1998) Multiple myeloma-associated amyloidosis and giant cell arteritis. Arthritis Rheum 41:1312–1317 Logar D, Rozman B, Vizjak A et al (1994) Arteritis of both internal carotid arteries in a patient with focal crescentic glomerulonephritis and antineutrophil cytoplasmic antibodies (c-ANCA). Br J Rheumatol 33:167–169 Muller E, Schneider W, Kettritz U et al (2004) Temporal ateritis with pauci-immune glomerulonephritis: a systemic disease. Clin Nephrol 62:384-386 Tanaka A, Tsujimoto I, Ito Y et al (2011) Temporal artery involvement in microscopic polyangitis. Intern Med 50:1033–1037 Ogawa O, Watanabe R, Shimizu H, Masani F (2011) Hypertensive crisis in young woman with Takayasu arteritis. Intern Med 50:1963–1967 Wada Y, Nishida H, Kohno K et al (1999) AA amyloidosis in Takayasu’s arteritis-long-term survival on maintenance haemodialysis. Nephrol Dial Transplant 14:2478–2481 Koga T, Nishino Y, Makiyama J et al (2010) Serum amyloid A is a useful marker to evaluate the disease activity of Takayasu’s arteritis. Rheumatol Int 30:561–563 Cavatorta F, Campisi S, Trabassi E et al (1995) IgA nephropathy associated with Takayasu’s arteritis: report of a case and review of the literature. Am J Nephrol 15:165–167 Li XM, Ye WL, Wen YB et al (2009) Glomerular disease associated with Takayasu arteritis: 6 cases analysis and review of the literature. Chin Med Sci J 24:69–75 Saxe PA, Altman RD (1992) Takayasu’s arteritis syndrome associated with systemic lupus erythematosus. Semin Arthritis Rheum 21:295–305 Kitazawa K, Joh K, Akizawa T (2008) A case of lupus nephritis coexisting with podocytic infolding associated with Takayasu’s arteritis. Clin Exp Nephrol 12:462–466 Sano N, Kitazawa K, Totsuka D et al (2002) A case of lupus nephritis with alteration of the glomerular basement membrane associated with Takayasu’s arteritis. Clin Nephrol 58:161–165 Jghaimi F, Kabbaj A, Essaadouni L (2010) Takayasu’s arteritis and retroperitoneal fibrosis: a case report. Rev Med Interne 31:1–3 Wagner AD (2011) Einsatz von Biologics bei Vaskulitiden großer Gefäße. In: Hellmich B (Hrsg) Biologics in der Therapie der Vaskulitiden. Uni-Med Verlag, Bremen, S 60–62 Young BR, Cook BE Jr, Bartley GB et al (2004) Initiation of glucocorticoid therapy: before and after temporal artery biopsy. Mayo Clin Proc 79:483–491 Penn H, Dasgupta B (2003) Giant cell arteritis. Autoimmun Rev 2:199–203 Mazlumzadeh M, Hunder GG, Easley KA et al (2006) Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum 54:3310–3318 Salvarani C, Cantini F, Niccoli L et al (2005) Acute-phase reactants and the risk of relaps/recurrence in polymyalgia rheumatica: a prospective follow up study. Arthritis Rheum 53:33–38 Nesher G, Berkun Y, Mates M et al (2004) Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteriitis. Athritis Rheum 50:1332–1337 Hoffman GS, Cid MC, Hellmann DB for the International Network for the Study of Systemic Vasculitides (2002) A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis. Arthritis Rheum 46:1309–1318 Jover JA, Hernandez-Garcia C, Morado IC et al (2001) Combined treatment of giant cell arteritis with methotrexate and prednisolone: a randomised, double blind, placebo-controlled trial. Ann Intern Med 134:106–114 Mahr AD, Jover JA, Spiera RF et al (2007) Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis. Arthritis Rheum 56:2789–2797 Hoffman GS, Cid MC, Weyand CM et al for the Infliximab-GCA Study Group (2007) Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis. Ann Intern Med 146:621–630 Martinez-Taboada VM, Rodriguez-Valverde V et al (2008) A double-blind placebo controlled trial of etanercept in patients with giant cell arteritis and corticosteroid side effects. Ann Rheum Dis 67:625–630 Hernandez-Rodriguez J, Segarra M, Vilardell C et al (2004) Tissue production of pro-inflammatory cytokines (IL-1β, TNFα and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis. Rheumatology (Oxford) 43:294–301 Cantini F, Niccoli L, Salvarani C et al (2001) Treatment of longstanding active giant cell arteritis with infliximab: report of four cases. Arthritis Rheum 44:2933–2935 Salvarani C, Cantini F, Niccoli L et al (2003) Treatment of refractory polymyalgia rheumatica with infliximab: a pilot study. J Rheumatol 33:760–763 Catanoso MG, Macchioni PL, Boiardi L et al (2007) Treatment of refractory polymyalgia rheumatica with etanercept: an open pilot study. Arthritis Rheum 57:1514–1519 Roche NE, Fulbright JW, Wagner AD et al (1993) Correlation of interleukin 6 production and disease activity in polymyalgia rheumatica and giant cell arteritis. Arthritis Rheum 36:1286–1294 Strand V, Yazici Y (2007) Interleukin-6 inhibition. Tolerability profile and clinical implications. Bull NYU Hosp JT Dis 65(Suppl 1):S21–24 Beyer C, Axmann R, Sahinbegovic E et al (2011) Anti-interleukin 6 receptor therapy as rescue treatment for giant cell arteritis. Ann Rheum Dis 70:1874–1875 Bhatia A, Ell PJ, Edwards JCW (2005) Anti-CD20 monoclonal antibody (rituximab) as an adjunct in the treatment of giant cell arteritis. Ann Rheum Dis 64:1099–1100 Jones RB, Tervaert JW, Hauser T et al (2010) Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. N Engl J Med 363:211–220 Stone JH, Merkel PA, Spiera R et al (2010) Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med 363:221–232 Liang P, Hoffman GS (2005) Advances in the medical and surgical treatment of Takayasu arteritis. Curr Opin Rheumatol 17:16–24 (Review) Hoffman GS, Merkel PA, Brasington Rd et al (2004) Anti-tumor necrosis factor therapy in patients with difficult to treat Takayasu arteritis. Arthritis Rheum 50:2296–2304 Hoyer BF, Mumtaz IM, Loddenkemper K et al (2012) Takayasu arteritis is characterized by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab. Ann Rheum Dis 71:75–79 Both M, Moosig F, Gross WL et al (2009) Großgefäßvaskulitiden. Radiologe 49:947–966