Nierenbeteiligung im Rahmen von Großgefäßvaskulitiden
Tóm tắt
Systemische Vaskulitiden sind entzündliche Erkrankungen der Gefäße, die den ganzen Körper befallen können. Die Einteilung erfolgt nach der Größe der betroffenen Gefäße. Zu den Großgefäßvaskulitiden gehören die Riesenzellarteriitis (RZA) und die Takayasu-Arteriitis (TA). Die RZA ist durch eine granulomatöse Entzündung der mittleren und großen Arterien charakterisiert. Sie ist die häufigste systemische Vaskulitis bei Personen über dem 50. Lebensjahr. Die TA ist als eine granulomatöse Vaskulitis der Aorta und ihrer Hauptäste definiert. Sie tritt typischerweise vor dem 40. Lebensjahr auf und ist in Europa vergleichsweise selten. Bei beiden Erkrankungen können neben anderen Organen auch die Nieren in unterschiedlichem Ausmaß betroffen sein. Im vorliegenden Artikel werden beide Vaskulitiden beschrieben und die jeweiligen Therapieoptionen aufgezeigt.
Tài liệu tham khảo
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