New trends for metal complexes with anticancer activity

Current Opinion in Chemical Biology - Tập 12 Số 2 - Trang 197-206 - 2008
Pieter C. A. Bruijnincx1, Peter J. Sadler1
1Department of Chemistry, University of Warwick, CV4 7AL, Coventry, United Kingdom

Tóm tắt

Từ khóa


Tài liệu tham khảo

Hambley, 2007, Developing new metal-based therapeutics: challenges and opportunities, Dalton Trans, 4929, 10.1039/b706075k

Orvig, 1999, Medicinal inorganic chemistry: introduction, Chem Rev, 99, 2201, 10.1021/cr980419w

Guo, 1999, Metals in medicine, Angew Chem Int Ed, 38, 1512, 10.1002/(SICI)1521-3773(19990601)38:11<1512::AID-ANIE1512>3.0.CO;2-Y

Thompson, 2006, Metal complexes in medicinal chemistry: new vistas and challenges in drug design, Dalton Trans, 761, 10.1039/B513476E

Jung, 2007, Direct cellular responses to platinum-induced DNA damage, Chem Rev, 107, 1387, 10.1021/cr068207j

van Zutphen, 2005, Targeting platinum anti-tumour drugs: overview of strategies employed to reduce systemic toxicity, Coord Chem Rev, 249, 2845, 10.1016/j.ccr.2005.03.005

Yang, 2007, Encapsulation of platinum anticancer drugs by apoferritin, Chem Commun, 3453, 10.1039/b705326f

MacDiarmid, 2007, Bacterially derived 400nm particles for encapsulation and cancer cell targeting of chemotherapeutics, Cancer Cell, 11, 431, 10.1016/j.ccr.2007.03.012

Hall, 2007, Basis for design and development of platinum(IV) anticancer complexes, J Med Chem, 50, 3403, 10.1021/jm070280u

Barnes, 2004, Synthesis, characterization, and cytotoxicity of a series of estrogen-tethered platinum(IV) complexes, Chem Biol, 11, 557, 10.1016/j.chembiol.2004.03.024

Ang, 2005, Rational design of platinum(IV) compounds to overcome glutathione-S-transferase mediated drug resistance, J Am Chem Soc, 127, 1382, 10.1021/ja0432618

Feazell, 2007, Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(IV) anticancer drug design, J Am Chem Soc, 129, 8438, 10.1021/ja073231f

Bednarski, 2006, Light-activated destruction of cancer cell nuclei by platinum diazide complexes, Chem Biol, 13, 61, 10.1016/j.chembiol.2005.10.011

Mackay, 2006, A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin, Chem Eur J, 12, 3155, 10.1002/chem.200501601

Heringova, 2006, Transplatin is cytotoxic when photoactivated: enhanced formation of DNA cross-links, J Med Chem, 49, 7792, 10.1021/jm0606692

Lutterman, 2006, cis-[Rh2(μ-O2CCH3)2(CH3CN)6]2+ as a photoactivated cisplatin analog, J Am Chem Soc, 128, 738, 10.1021/ja057620q

Ang, 2006, Classical and non-classical ruthenium-based anticancer drugs: Towards targeted chemotherapy, Eur J Inorg Chem, 4003, 10.1002/ejic.200600723

Liu, 2006, Diversity in guanine-selective DNA binding modes for an organometallic ruthenium arene complex, Angew Chem Int Ed, 45, 8153, 10.1002/anie.200602873

Habtemariam, 2006, Structure–activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands, J Med Chem, 49, 6858, 10.1021/jm060596m

Yan, 2005, Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes, Chem Commun, 4764, 10.1039/b508531b

Peacock, 2007, Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity, J Am Chem Soc, 129, 3348, 10.1021/ja068335p

Dyson, 2006, Metal-based antitumour drugs in the post genomic era, Dalton Trans, 1929, 10.1039/b601840h

Timerbaev, 2006, Interactions of antitumor metallodrugs with serum proteins: Advances in characterization using modern analytical methodology, Chem Rev, 106, 2224, 10.1021/cr040704h

Calderone, 2006, Structural investigation of cisplatin-protein interactions: Selective platination of His19 in a cuprozinc superoxide dismutase, Angew Chem Int Ed, 45, 1267, 10.1002/anie.200502599

McNae, 2004, Half-sandwich arene ruthenium(II)-enzyme complex, Chem Commun, 1786, 10.1039/B408141B

Casini, 2007, ESI-MS characterisation of protein adducts of anticancer ruthenium(II)–arene PTA (RAPTA) complexes, Chem Med Chem, 2, 631, 10.1002/cmdc.200600258

Weidt, 2007, Platination of superoxide dismutase with cisplatin: tracking the ammonia ligands using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), Chem Commun, 1719, 10.1039/b701903c

Reed, 2006, Stabilization of G-quadruplex DNA and inhibition of telomerase activity by square-planar nickel(II) complexes, J Am Chem Soc, 128, 5992, 10.1021/ja058509n

Dixon, 2007, A G-quadruplex ligand with 10000-fold selectivity over duplex DNA, J Am Chem Soc, 129, 1502, 10.1021/ja065591t

Komeda, 2006, A third mode of DNA binding: Phosphate clamps by a polynuclear platinum complex, J Am Chem Soc, 128, 16092, 10.1021/ja062851y

Harris, 2005, Synthesis, characterization, and cytotoxicity of a novel highly charged trinuclear platinum compound. Enhancement of cellular uptake with charge, Inorg Chem, 44, 9598, 10.1021/ic051390z

Oleksi, 2006, Molecular recognition of a three-way DNA junction by a metallosupramolecular helicate, Angew Chem Int Ed, 45, 1227, 10.1002/anie.200503822

Hannon, 2007, Supramolecular DNA recognition, Chem Soc Rev, 36, 280, 10.1039/B606046N

Pascu, 2007, Dinuclear ruthenium(II) triple-stranded helicates: Luminescent supramolecular cylinders that bind and coil DNA and exhibit activity against cancer cell lines, Angew Chem Int Ed, 46, 4374, 10.1002/anie.200700656

Hotze, 2006, Dinuclear double-stranded metallosupramolecular ruthenium complexes: potential anticancer drugs, Angew Chem Int Ed, 45, 4839, 10.1002/anie.200601351

Meggers, 2007, Exploring chemical space with organometallics: Ruthenium complexes as protein kinase inhibitors, Synlett, 1177, 10.1055/s-2007-973893

Bregman, 2006, Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: discovery of potent and selective protein kinase inhibitors, J Am Chem Soc, 128, 877, 10.1021/ja055523r

Debreczeni, 2006, Ruthenium half-sandwich complexes bound to protein kinase Pim-1, Angew Chem Int Ed, 45, 1580, 10.1002/anie.200503468

Smalley, 2007, An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells, Cancer Res, 67, 209, 10.1158/0008-5472.CAN-06-1538

Urig, 2006, On the potential of thioredoxin reductase inhibitors for cancer therapy, Semin Cancer Biol, 16, 452, 10.1016/j.semcancer.2006.09.004

Urig, 2006, Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases, Angew Chem Int Ed, 45, 1881, 10.1002/anie.200502756

Barnard, 2007, Targeting the mitochondrial cell death pathway with gold compounds, Coord Chem Rev, 251, 1889, 10.1016/j.ccr.2007.04.006

Sun, 2007, Some uses of transition metal complexes as anti-cancer and anti-HIV agents, Dalton Trans, 4884

Wang, 2006, Proteomic characterization of the cytotoxic mechanism of gold(III) porphyrin 1a, a potential anticancer drug, Proteomics, 6, 131, 10.1002/pmic.200402027

Milacic, 2006, A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts, Cancer Res, 66, 10478, 10.1158/0008-5472.CAN-06-3017

Ott, 2005, Antitumor-active cobalt–alkyne complexes derived from acetylsalicylic acid: Studies on the mode of drug action, J Med Chem, 48, 622, 10.1021/jm049326z

Failes, 2007, Studies of a cobalt(III) complex of the MMP inhibitor marimastat: A potential hypoxia-activated prodrug, Chem Eur J, 13, 2974, 10.1002/chem.200601137

Bergamo, 2007, Ruthenium complexes can target determinants of tumour malignancy, Dalton Trans, 1267, 10.1039/b617769g

Scolaro, 2005, In vitro and in vivo evaluation of ruthenium(II)–arene PTA complexes, J Med Chem, 48, 4161, 10.1021/jm050015d

Schatzschneider, 2006, New principles in medicinal organometallic chemistry, Angew Chem Int Ed, 45, 1504, 10.1002/anie.200504604

Hillard, 2006, Ferrocene-mediated proton-coupled electron transfer in a series of ferrocifen-type breast-cancer drug candidates, Angew Chem Int Ed, 45, 285, 10.1002/anie.200502925

James, 2006, Enantioselective synthesis of ferrocenyl nucleoside analogues with apoptosis-inducing activity, Org Lett, 8, 2763, 10.1021/ol060868f

Schlawe, 2004, Iron-containing nucleoside analogues with pronounced apoptosis-inducing activity, Angew Chem Int Ed, 43, 1731, 10.1002/anie.200353132

Noor, 2005, A cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery, Angew Chem Int Ed, 44, 2429, 10.1002/anie.200462519

Mackay, 2007, A potent cytotoxic photoactivated platinum complex, PNAS, 104, 20743, 10.1073/pnas.0707742105