New mesalamine polymeric conjugate for controlled release: Preparation, characterization and biodistribution study

Abinusawa, 2015, Release of 5-aminosalicylic acid (5-ASA) from mesalamine formulations at various pH levels, Adv. Ther., 32, 477, 10.1007/s12325-015-0206-4 Ahmad, 2006, Dextran and 5-aminosalicylic acid (5-ASA) conjugates: synthesis, characterisation and enzymic hydrolysis, Carbohydr. Res., 341, 2694, 10.1016/j.carres.2006.08.015 Bansal, 2015, Benzimidazoleeibuprofen/mesalamine conjugates: potential candidates for multifactorial diseases, Eur. J. Med. Chem., 89, 671, 10.1016/j.ejmech.2014.10.081 Baumgart, 2007, Inflammatory bowel disease: clinical aspects and established and evolving therapies, Lancet, 369, 1641, 10.1016/S0140-6736(07)60751-X Campana, 2015, Anti-TNF-α activity of Brazilian medicinal plants and compounds from Ouratea semiserrata, Phytother. Res., 29, 1509, 10.1002/ptr.5401 Canevari, 2009, Poly(ethylene glycol)-mesalazine conjugate for colon specific delivery, Int. J. Pharm., 368, 171, 10.1016/j.ijpharm.2008.09.058 Cañas, 2010, Chondroitin sulfate inhibits lipopolysaccharide-induced inflammation in rat astrocytes by preventing nuclear factor kappa B activation, Neuroscience, 167, 872, 10.1016/j.neuroscience.2010.02.069 Chang, 2009, Fabrication and characterization of poly (γ-glutamic acid)-graft-chondroitin sulfate/polycaprolactone porous scaffolds for cartilage tissue engineering, Acta Biomater., 5, 1937, 10.1016/j.actbio.2009.02.002 Clayden, 2012 Corridoni, 2014, Inflammatory bowel disease, Immunol. Lett., 161, 231, 10.1016/j.imlet.2014.04.004 Costa, 2001, Modeling and comparison of dissolution profiles, Eur. J. Pharm. Sci., 13, 123, 10.1016/S0928-0987(01)00095-1 da Silva, 2014, Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis, World J. Gastroenterol., 20, 9458, 10.3748/wjg.v20.i28.9458 Duncan, 2003, The dawning era of polymer therapeutics, Nat. Rev. Drug Discov., 2, 347, 10.1038/nrd1088 Ergün, 2004, Characterization of the role of physicochemical factors on the hydrolysis of dipyrone, J. Pharm. Biomed. Anal., 35, 479, 10.1016/j.jpba.2004.02.004 Ham, 2012, Mesalamine in the treatment and maintenance of remission of ulcerative colitis, Expert. Rev. Clin. Pharmacol., 5, 113, 10.1586/ecp.12.2 Henrotin, 2010, Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations, Ther. Adv. Musculoskelet. Dis., 2, 335, 10.1177/1759720X10383076 Jing, 2012, Synthesis and characterization of folic acid modified water-soluble chitosan derivatives for folate-receptor-mediated targeting, Bioorg. Med. Chem. Lett., 22, 3418, 10.1016/j.bmcl.2012.03.102 Kopeček, 2013, Polymer-drug conjugates: origins, progress to date and future directions, Adv. Drug Deliv. Rev., 65, 49, 10.1016/j.addr.2012.10.014 Lee, 2007, Synthesis and characterizations of amphiphilic poly(l-lactide)-grafted chondroitin sulfate copolymer and its application as drug carrier, Biomol. Eng., 24, 131, 10.1016/j.bioeng.2006.05.010 Li, 2015, Biodegradable polymer nanogels for drug/nucleic acid delivery, Chem. Rev., 115, 8564, 10.1021/cr500131f Mladenovska, 2007, Colon-specific delivery of 5-aminosalicylic acid from chitosan-Ca-alginate microparticles, Int. J. Pharm., 342, 124, 10.1016/j.ijpharm.2007.05.028 Mladenovska, 2007, 5-ASA loaded chitosan–Ca–alginate microparticles: preparation and physicochemical characterization, Int. J. Pharm., 345, 59, 10.1016/j.ijpharm.2007.05.059 Murakami, 2006, Bio-based hydrogels prepared by cross-linking of microbial poly(ç-glutamic acid) with various saccharides, Biomacromolecules, 7, 2122, 10.1021/bm0600264 Ordás, 2012, Ulcerative colitis, Lancet, 380, 1606, 10.1016/S0140-6736(12)60150-0 Ozgur, 2012, Synthesis and biological evaluation of radiolabeled photosensitizer linked bovine serum albumin nanoparticles as a tumor imaging agent, Int. J. Pharm., 422, 472, 10.1016/j.ijpharm.2011.11.013 Pasut, 2007, Polymer-drug conjugation, recent achievements and general strategies, Prog. Polym. Sci., 32, 933, 10.1016/j.progpolymsci.2007.05.008 Quetglas, 2015, Review article: the pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment, Eur. J. Clin. Pharmacol., 71, 773, 10.1007/s00228-015-1862-7 Ritger, 1987, A simple equation for description of solute release II. Fickian and anomalous release from swellable devices, J. Control. Release, 5, 37, 10.1016/0168-3659(87)90035-6 Shrivastava, 2013, Dextran Carrier macromolecules for colon-specific delivery of 5-aminosalicylic acid, Indian J. Pharm. Sci., 75, 277, 10.4103/0250-474X.117420 Silverstein, 2000 Sobal, 2007, Radiolabeling procedure, quality control and stability of 99mTc-labeled chondroitin sulfate: a new approach of targeting osteoarthritis, Appl. Radiat. Isot., 66, 415, 10.1016/j.apradiso.2007.11.002 Varum, 2008, Mucoadhesion and the gastrointestinal tract, Crit. Rev. Ther. Drug Carrier Syst., 25, 207, 10.1615/CritRevTherDrugCarrierSyst.v25.i3.10 Walsh, 2011, Inflammatory bowel disease, Prim. Care, 38, 415, 10.1016/j.pop.2011.06.001 Xu, 2014, Preparation and evaluation of colon adhesive pellets of 5-aminosalicylic acid, Int. J. Pharm., 468, 165, 10.1016/j.ijpharm.2014.04.040