New insights into E-protein function in lymphocyte development

Trends in Immunology - Tập 26 - Trang 334-338 - 2005
Adam Lazorchak1, Mary Elizabeth Jones1, Yuan Zhuang1
1Department of Immunology, Duke University Medical Center, Durham, NC 27710 USA

Tài liệu tham khảo

Jan, 1993, HLH proteins, fly neurogenesis, and vertebrate myogenesis, Cell, 75, 827, 10.1016/0092-8674(93)90525-U Jones, 2004, An overview of the basic helix–loop–helix proteins, Genome Biol., 5, 226, 10.1186/gb-2004-5-6-226 Henthorn, 1990, Two distinct transcription factors that bind the immunoglobulin enhancer microE5/κ2 motif, Science, 247, 467, 10.1126/science.2105528 Hu, 1992, HEB, a helix–loop–helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors, Mol. Cell. Biol., 12, 1031, 10.1128/MCB.12.3.1031 Lassar, 1991, Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo, Cell, 66, 305, 10.1016/0092-8674(91)90620-E Bain, 1993, E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins, Mol. Cell. Biol., 13, 3522, 10.1128/MCB.13.6.3522 Murre, 1989, A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins, Cell, 56, 777, 10.1016/0092-8674(89)90682-X Quong, 2002, E protein function in lymphocyte development, Annu. Rev. Immunol., 20, 301, 10.1146/annurev.immunol.20.092501.162048 Busslinger, 2004, Transcriptional control of early B cell development, Annu. Rev. Immunol., 22, 55, 10.1146/annurev.immunol.22.012703.104807 Smith, 2004, The roles of transcription factors in B lymphocyte commitment, development, and transformation, J. Leukoc. Biol., 75, 973, 10.1189/jlb.1103554 Sun, 2004, Multitasking of helix–loop–helix proteins in lymphopoiesis, Adv. Immunol., 84, 43, 10.1016/S0065-2776(04)84002-1 Zhuang, 1994, The helix–loop–helix gene E2A is required for B cell formation, Cell, 79, 875, 10.1016/0092-8674(94)90076-0 Bain, 1994, E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements, Cell, 79, 885, 10.1016/0092-8674(94)90077-9 Bain, 1999, Thymocyte maturation is regulated by the activity of the helix–loop–helix protein, E47, J. Exp. Med., 190, 1605, 10.1084/jem.190.11.1605 Zhuang, 1996, B-lymphocyte development is regulated by the combined dosage of three basic helix–loop–helix genes, E2A, E2-2, and HEB, Mol. Cell. Biol., 16, 2898, 10.1128/MCB.16.6.2898 Barndt, 1999, A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during αβ thymopoiesis, J. Immunol., 163, 3331, 10.4049/jimmunol.163.6.3331 Sawada, 1993, A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines, Mol. Cell. Biol., 13, 5620, 10.1128/MCB.13.9.5620 Barndt, 2000, Functions of E2A–HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB, Mol. Cell. Biol., 20, 6677, 10.1128/MCB.20.18.6677-6685.2000 Zhuang, 1998, Functional replacement of the mouse E2A gene with a human HEB cDNA, Mol. Cell. Biol., 18, 3340, 10.1128/MCB.18.6.3340 Barndt, 1999, Controlling lymphopoiesis with a combinatorial E-protein code, Cold Spring Harb. Symp. Quant. Biol., 64, 45, 10.1101/sqb.1999.64.45 Herblot, 2002, Gradient of E2A activity in B-cell development, Mol. Cell. Biol., 22, 886, 10.1128/MCB.22.3.886-900.2002 Quong, 2004, Receptor editing and marginal zone B cell development are regulated by the helix–loop–helix protein, E2A, J. Exp. Med., 199, 1101, 10.1084/jem.20031180 Bain, 1999, Positive and negative regulation of V(D)J recombination by the E2A proteins, J. Exp. Med., 189, 289, 10.1084/jem.189.2.289 Bain, 2001, Regulation of the helix–loop–helix proteins, E2A and Id3, by the Ras–ERK–MAPK cascade, Nat. Immunol., 2, 165, 10.1038/84273 Jen, 1996, Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis, Dev. Dyn., 207, 235, 10.1002/(SICI)1097-0177(199611)207:3<235::AID-AJA1>3.0.CO;2-I Wilson, 1991, Repression of immunoglobulin enhancers by the helix–loop–helix protein Id: implications for B-lymphoid-cell development, Mol. Cell. Biol., 11, 6185, 10.1128/MCB.11.12.6185 Sun, 1994, Constitutive expression of the Id1 gene impairs mouse B cell development, Cell, 79, 893, 10.1016/0092-8674(94)90078-7 Ikawa, 2004, Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent, Immunity, 20, 349, 10.1016/S1074-7613(04)00049-4 Zhuang, 2004, Regulation of E2A gene expression in B-lymphocyte development, Mol. Immunol., 40, 1165, 10.1016/j.molimm.2003.11.031 Heemskerk, 1997, Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3, J. Exp. Med., 186, 1597, 10.1084/jem.186.9.1597 Yokota, 1999, Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2, Nature, 397, 702, 10.1038/17812 Ordentlich, 1998, Notch inhibition of E47 supports the existence of a novel signaling pathway, Mol. Cell. Biol., 18, 2230, 10.1128/MCB.18.4.2230 Maillard, 2003, Notch and the immune system, Immunity, 19, 781, 10.1016/S1074-7613(03)00325-X Huang, 2004, Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination, Mol. Cell. Biol., 24, 8951, 10.1128/MCB.24.20.8951-8962.2004 DeKoter, 2002, PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors, Immunity, 16, 297, 10.1016/S1074-7613(02)00269-8 Scott, 1994, Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages, Science, 265, 1573, 10.1126/science.8079170 DeKoter, 2000, Regulation of B lymphocyte and macrophage development by graded expression of PU.1, Science, 288, 1439, 10.1126/science.288.5470.1439 Kee, 1998, Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix–loop–helix transcription factor E12, J. Exp. Med., 188, 699, 10.1084/jem.188.4.699 Smith, 2002, Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression, J. Immunol., 169, 261, 10.4049/jimmunol.169.1.261 Seet, 2004, Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A, J. Exp. Med., 199, 1689, 10.1084/jem.20032202 Medina, 2004, Assembling a gene regulatory network for specification of the B cell fate, Dev. Cell, 7, 607, 10.1016/j.devcel.2004.08.006 O'Riordan, 1999, Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A, Immunity, 11, 21, 10.1016/S1074-7613(00)80078-3 Mansson, 2004, Pearson correlation analysis of microarray data allows for the identification of genetic targets for early B-cell factor, J. Biol. Chem., 279, 17905, 10.1074/jbc.M400589200 Maier, 2004, Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription, Nat. Immunol., 5, 1069, 10.1038/ni1119 Greenbaum, 2002, Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system, Proc. Natl. Acad. Sci. U. S. A., 99, 15030, 10.1073/pnas.232299999 Hsu, 2003, A conserved transcriptional enhancer regulates RAG gene expression in developing B cells, Immunity, 19, 105, 10.1016/S1074-7613(03)00181-X Greenbaum, 2004, Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes, J. Biol. Chem., 279, 45028, 10.1074/jbc.M400061200 Romanow, 2000, E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells, Mol. Cell, 5, 343, 10.1016/S1097-2765(00)80429-3 Inlay, 2004, Important roles for E protein binding sites within the immunoglobulin κ chain intronic enhancer in activating VκJκ rearrangement, J. Exp. Med., 200, 1205, 10.1084/jem.20041135 Inlay, 2002, Essential roles of the κ light chain intronic enhancer and 3′ enhancer in κ rearrangement and demethylation, Nat. Immunol., 3, 463, 10.1038/ni790 Ephrussi, 1985, B lineage-specific interactions of an immunoglobulin enhancer with cellular factors in vivo, Science, 227, 134, 10.1126/science.3917574 Brekke, 2004, Assembly and analysis of the mouse immunoglobulin κ gene sequence, Immunogenetics, 56, 490, 10.1007/s00251-004-0659-0 Eckner, 1996, Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation, Genes Dev., 10, 2478, 10.1101/gad.10.19.2478 Massari, 1999, A conserved motif present in a class of helix–loop–helix proteins activates transcription by direct recruitment of the SAGA complex, Mol. Cell, 4, 63, 10.1016/S1097-2765(00)80188-4 Bradney, 2003, Regulation of E2A activities by histone acetyltransferases in B lymphocyte development, J. Biol. Chem., 278, 2370, 10.1074/jbc.M211464200