New developments in the biochemical assessment of myocardial injury in children: troponins T and I as highly sensitive and specific markers of myocardial injury

Progress in Pediatric Cardiology - Tập 8 - Trang 71-81 - 1997
M.E Ottlinger1, L Pearsall2, N Rifai3, S.E Lipshultz4
1Department of Pathology and Laboratory Medicine, Boston Veteran's Administration Medical Center, 150 South Huntington Avenue, Boston, MA 02130, USA and Department of Pathology, Boston University School of Medicine
2Department of Pediatrics, Children's Hospital at Strong and University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA
3Department of Laboratory Medicine, Children's Hospital, 300 Longwood Avenue, Boston, MA, USA and Department of Pathology, Harvard Medical School
4Division of Pediatric Cardiology, Children's Hosptial at Strong and University of Rochester Medical Center, Box 631, 601 Elmwood Avenue, Rochester, NY, USA and Department of Pediatrics, University of Rochester School of Medicine and Dentistry

Tài liệu tham khảo

Katus, 1992, Proteins of the troponin complex, Lab Med, 23, 311, 10.1093/labmed/23.5.311 Nascimben, 1996, Creatine kinase system in failing and nonfailing human myocardium, Circulation, 94, 1894, 10.1161/01.CIR.94.8.1894 Keffer, 1996, Myocardial markers of injury: evolution and insights, Clin Chem, 105, 305 El Allaf, 1986, Differentiating muscle damage from myocardial injury by means of the serum creatine kinase (CK) isoenzyme MB mass measurement/total CK activity ratio, Clin Chem, 32, 291, 10.1093/clinchem/32.2.291 Braunwald, 1994, Diagnosing and managing unstable angina, Circulation, 90, 613, 10.1161/01.CIR.90.1.613 Piper, 1984, Early enzyme release from myocardial cells is not due to irreversible cell damage, J Mol Cell Cardiol, 16, 385, 10.1016/S0022-2828(84)80609-4 Wu, 1994, Cardiac troponin T immunoassay for diagnosis of acute myocardial infarction, Clin Chem, 40, 900, 10.1093/clinchem/40.6.900 Burlina A, Zaninotto M, Secchiero S, Rubin D, Accorsi F. Troponin T as a marker of ischemic myocardial injury. Clin Biochem, 27:113–121. Antman, 1995, Evaluation of a rapid bedside assay for detection of serum cardiac troponin T, J Am Med Assoc, 273, 1279, 10.1001/jama.1995.03520400049043 Adams, 1994, Clin Chem, 40, 1291, 10.1093/clinchem/40.7.1291 Gerhardt, 1991, Clin Chem, 37, 1405, 10.1093/clinchem/37.8.1405 Hamm, 1992, The prognostic value of serum troponin T in unstable angina, N Engl J Med, 327, 146, 10.1056/NEJM199207163270302 Hamm, 1997, Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I, N Engl J Med, 337, 1648, 10.1056/NEJM199712043372302 Bakker, 1994, Troponin T and myoglobin at admission: value of early diagnosis of acute myocardial infarction, Eur Heart J, 15, 45, 10.1093/oxfordjournals.eurheartj.a060378 Efthymiadis, 1994, The diagnostic value of the determination of troponin T in the diagnosis of unstable angina, Acta Cardiol, XLIX, 419 Ravkilde, 1994, Cardiac troponin T and CK-MB mass release after visually successful percutaneous transluminal coronary angioplasty in stable angina pectoris, Am Heart J, 127, 13, 10.1016/0002-8703(94)90504-5 Antman, 1996, Cardiac-specific troponin I levels to predict the rise of mortality in patients with acute coronary syndromes, N Eng J Med, 335, 1342, 10.1056/NEJM199610313351802 Salvadori, 1992, Creatine kinase and creatine kinase-MB isoenzyme during and after exercise testing in normal and obese young people, Chest, 102, 1687, 10.1378/chest.102.6.1687 Cohen, 1996, Troponin I in hypothyroidism, Clin Chem, 42, 1494, 10.1093/clinchem/42.9.1494 Burnett, 1994, Serum enzymes in hypothyroidism, N Z Med J, 107, 355 Maguire, 1991, Cardiotoxicity during treatment of severe childhood asthma pediatrics, ?, 88, 1180 Rama, 1996, Troponin I immunoenzymometric assays for detection of muscle damage applied to monitoring a triathalon, Clin Chem, 42, 2033, 10.1093/clinchem/42.12.2033 Rifai, 1996, Myocardial injury in athletes participating in the Hawaii ironman triathlon, (Abstr), Circulation, 94, I Grubb, 1996, Resuscitation from out-of-hospital cardiac arrest, Resuscitation, 33, 35, 10.1016/S0300-9572(96)00971-9 Bonnefoy, 1997, Cardiac troponin I does not increase after cardioversion, Chest, 111, 15, 10.1378/chest.111.1.15 Keshgegian, 1984, Serum creatine kinase MB isoenzyme in chronic muscle disease, Clin Chem, 30, 575, 10.1093/clinchem/30.4.575 Mahalingham, 1996, A case against the specificity of cardiac troponin-T, J Clin Pathol, 49, 766, 10.1136/jcp.49.9.766 Thygesan, 1986, Creatine kinase and creatine kinase B-subunit in stable and unstable angine pectoris, Eur J Clin Invest, 16, 1, 10.1111/j.1365-2362.1986.tb01298.x Braunwald, 1989, Unstable angina: a classification, Circulation, 80, 410, 10.1161/01.CIR.80.2.410 Botker, 1991, Gradation of unstable angina based on a sensitive immunoassay for creatine kinase MB, Br Heart J, 65, 72, 10.1136/hrt.65.2.72 Lipshultz, 1997, Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury, Circulation, 96, 2641, 10.1161/01.CIR.96.8.2641 Tagger, 1996, Vulnerability of pediatric myocardium to cardiac surgery, Heart, 76, 214, 10.1136/hrt.76.3.214 Taggert, 1997, Effects of age and ischemic time on biochemical evidence of myocardial injury after pediatric cardiac operations, J Thorac Cardiovasc Surg, 113, 728, 10.1016/S0022-5223(97)70231-9 Kaukoranta, 1997, Normothermic retrograde blood cardioplegia with or without preceding ischemic preconditioning, Ann Thorac Surg, 63, 1268, 10.1016/S0003-4975(97)00100-8 Oliver, 1994, Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias, Lancet, 343, 155, 10.1016/S0140-6736(94)90939-3 Kjellman, 1995, Alpha-ketoglutarate for myocardial protection in heart surgery, Lancet, 345, 552, 10.1016/S0140-6736(95)90466-2 Wendel, 1995, Lower cardiac troponin T levels in patients undergoing cardiopulmonary bypass and receiving high-dose aprotinin therapy indicate reduction of perioperative myocardial damage, J Thorac Cardiovasc Surg, 109, 1164, 10.1016/S0022-5223(95)70200-8 Grant, 1994, Elevated donor cardiac troponin T: A marker of acute graft failure in infant heart recipients, Circulation, 90, 2618, 10.1161/01.CIR.90.6.2618 Franz, 1996, Serum troponin T: diagnostic marker for acute myocarditis, Clin Chem, 42, 340, 10.1093/clinchem/42.2.340 Smith, 1997, Elevations of cardiac troponin I associated with myocarditis, Circulation, 95, 163, 10.1161/01.CIR.95.1.163 Wong, 1997, Does clinically unsuspected myocardial injury occur in children? Abstract, Pediatr Res, 41, 101A, 10.1203/00006450-199704001-00609 Lipshultz SE, Grenier MA. Left ventricular dysfunction in infants and children infected with the human immunodeficiency virus. Prog Pediatr Cardiol 1997:33–43. Finkel, 1993, Interleukin-6 (IL-6) as a mediator of stunned myocardium, Am J Cardiol, 71, 1231, 10.1016/0002-9149(93)90654-U Nishigaki, 1997, Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in patients with chronic congestive heart failure, J Am Coll Cardiol, 29, 1214, 10.1016/S0735-1097(97)00055-7 Takada, 1995, Therapy with immunoglobin suppresses myocarditis in a murine coxsackievirus B3 model, Circulation, 92, 1604, 10.1161/01.CIR.92.6.1604 Lipshultz, 1991, Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood, N Engl J Med, 324, 808, 10.1056/NEJM199103213241205 Lipshultz, 1995, Female sex and higher drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer, N Engl J Med, 332, 1738, 10.1056/NEJM199506293322602 Dorr, 1996, Cytoprotective agents for anthracyclines, Semin Oncol, 23, 23 Ottlinger, 1995, Myocardial damage in doxorubicin-treated children: a study of serum cardiac troponin T. Abstr, Proc Am Soc Clin Oncol, 14, 345 Missov, 1996, Increased circulating cardiac troponin I in anthracycline-treated patients (Abstr), Circulation, 94, I Fink, 1995, Cardiac troponin T and creatine kinase MB mass concentrations in children receiving anthracycline chemotherapy, Med Pediatr Oncol, 25, 185, 10.1002/mpo.2950250305 Herman, 1998, Use of cardiac troponin-T levels as an indicator of doxorubicin-induced cardiotoxicity, Cancer Res:, 58, 195 Adams, 1996, Improved detection of cardiac contusion with cardiac troponin I, Am Heart J, 131, 308, 10.1016/S0002-8703(96)90359-2 Langer, 1989, Diagnosis and incidence of cardiac injury in children with blunt thoracic trauma, J Pediatr Surg, 24, 1091, 10.1016/S0022-3468(89)80225-8 Mair, 1991, Cardiac troponin T in the diagnosis of heart contusion, Lancet, 338, 693, 10.1016/0140-6736(91)91266-W Hirsch, 1997, Cardiac troponin I in pediatrics: normal values and potential use and potential in the assessment of cardiac injury, J Pediatr, 130, 872, 10.1016/S0022-3476(97)70271-3 Fischer, 1996, Troponin T in monitoring of myocardial injury in critically ill children (Abstr), Circulation, 94, 156 Panteghini, 1997, Cardiac troponin T in serum as a marker for myocardial injury in newborns, Clin Chem, 43, 1455, 10.1093/clinchem/43.8.1455 Braun, 1996, Discrepant results for cardiac troponin T and troponin I in chronic myopathy, depending on instrument and assay generation, Clin Chem, 42, 2039, 10.1093/clinchem/42.12.2039 Bhayana, 1995, Discordance between results for serum troponin T and troponin I in renal disease, Clin Chem, 41, 312, 10.1093/clinchem/41.2.312 Jabs, 1996, Elevations of serum troponin T (TnT) and I (TnI) levels and cardiac abnormalities in children with chronic renal failure (CRF). (Abstr), J Am Soc Nephrol, 9, 1320 Somers MJG, Rifai N, Colan SD, Harmon W, Lipshultz SE. Abnormalities in echocardiography and biochemical cardiac markers in children and young adults with chronic renal failure (CRF) (Abstr). J Am Soc Nephrol 1997:in press. Bodor, 1995, Cardiac troponin I is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue, Clin Chem, 41, 1710, 10.1093/clinchem/41.12.1710