New developments in stem cell biology and therapy. meeting report from the working group of the German Society for Hematology and Oncology

Besser, 2004, Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3, J Biol Chem, 279, 45076, 10.1074/jbc.M404979200 Wagner, 2004, Molecular evidence for stem cell function of the slow-dividing fraction among human hematopoietic progenitor cells by genome-wide analysis, Blood, 104, 675, 10.1182/blood-2003-10-3423 Schiedlmeier, 2003, High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation, Blood, 101, 1759, 10.1182/blood-2002-03-0767 Jundt, 2004, Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells, Blood, 103, 3511, 10.1182/blood-2003-07-2254 Göthert, 2005, In vivo fate-tracing studies using the SCL stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis, Blood, 105, 2724, 10.1182/blood-2004-08-3037 Roeder, 2005, Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization, Blood, 105, 609, 10.1182/blood-2004-01-0282 Bieback, 2004, Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood, Stem Cells, 22, 625, 10.1634/stemcells.22-4-625 Stamm, 2003, Autologous bone marrow stem cell transplantation for myocardial regeneration, Lancet, 361, 45, 10.1016/S0140-6736(03)12110-1 Stark, 2004, Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermo-epidermal junction in organotypic co-culture, Eur J Cell Biol, 83, 631, 10.1078/0171-9335-00435 Spyridonidis, 2004, Epithelial tissue chimerism after human hematopoietic cell transplantation is a real phenomenon, Am J Pathol, 164, 1147, 10.1016/S0002-9440(10)63203-8 Kuçi, 2003, Identification of a novel class of human adherent CD34– stem cells that give rise to SCID-repopulating cells, Blood, 101, 869, 10.1182/blood-2002-03-0711 Klein, 2004, Related articles links the possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia, Crit Rev Oncol Hematol, 50, 87, 10.1016/j.critrevonc.2003.09.001 Hart, 2004, Expression and function of homing-essential molecules and enhanced in vivo homing ability of human peripheral blood-derived hematopoietic progenitor cells after stimulation with stem cell factor, Stem Cells, 22, 580, 10.1634/stemcells.22-4-580 Becker, 2004, Transfer of the multidrug resistance gene, MDR-1, yo hematopoietic progenitors from a patient with transformed large cell lymphoma, and demonstration of in vivo chemotherapy protection with dose escalating chemotherapy [abstract], Blood, 104, 5278, 10.1182/blood.V104.11.5278.5278 Nagy, 2004, Clonal analysis of individual marrow-repopulating cells after experimental peripheral blood progenitor cell transplantation, Stem Cells, 22, 570, 10.1634/stemcells.22-4-570 Laufs, 2004, Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns, Mol Ther, 10, 874, 10.1016/j.ymthe.2004.08.001 Fischer, 2005, Related articles, links integration of retroviruses: a fine balance between efficiency and danger, PLoS Med, 2, e10, 10.1371/journal.pmed.0020010 Buschfort-Papewalis, 2002, Down-regulation of DNA repair in human CD34(+) progenitor cells corresponds to increased drug sensitivity and apoptotic response, Blood, 100, 845, 10.1182/blood-2002-01-0022 Jansen, 2002, Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells, Cancer Gene Ther, 9, 737, 10.1038/sj.cgt.7700490 Ciccolini, 2003, Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation, J Neurosci, 23, 103, 10.1523/JNEUROSCI.23-01-00103.2003 Henschler, 2004, A mouse model to study organ homing behaviour of haemopoietic progenitor cells reveals high selectivity but low efficiency of multipotent progenitors to home into haemopoietic organs, Br J Haematol, 126, 111, 10.1111/j.1365-2141.2004.04995.x