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Depsidone và dichromone mới từ thân cây Garcinia paucinervis với hoạt tính chống phát triển tế bào
Tóm tắt
Một depsidone mới, paucinervin Q (1), một dichromone mới, paucinervin R (2), và một hợp chất đã biết, paucinervin B (3), đã được phân lập từ thân cây Garcinia paucinervis bằng các phương pháp sắc ký khác nhau. Cấu trúc của các hợp chất được xác định thông qua phân tích dữ liệu quang phổ. Các hợp chất phân lập được đánh giá về hoạt tính chống phát triển tế bào đối với ba dòng tế bào ung thư HL-60, PC-3 và CaCo-2. Hợp chất 1 cho thấy hoạt tính ức chế đáng kể.
Từ khóa
#depsidone #dichromone #Garcinia paucinervis #hoạt tính chống phát triển tế bào #HL-60 #PC-3 #CaCo-2Tài liệu tham khảo
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