New antiepileptic drugs

Shorvon, 1994, Emergency treatment of epileptic status, 175 1989, Commission on Classification and Terminology of the International League Against Epilepsy, Proposal for classification of epilepsies and epileptic syndromes, 30, 389 Gram, 1990, Epileptic seizures and syndromes, Lancet, 336, 161, 10.1016/0140-6736(90)91672-W Wallace, 1989, Prescribing anticonvulsant drugs: 4 ethosuximide, Prescriber's Journal, 29, 258 Perlin, 1992, Calcium and epilepsy, 15 Brodie, 1990, Established anticonvulsants and treatment of refractory epilepsy, Lancet, 336, 350, 10.1016/0140-6736(90)91886-F Brodie, 1989, Prescribing anticonvulsant drugs: 1 sodium valproate, Prescriber's Journal, 29, 30 Christe, 1989, Valproate in juvenile myoclonic epilepsy, 91 Brodie, 1992, Drugs in focus: 1 vigabatrin, Prescriber's Journal, 32, 21 Duncan, 1994, Vigabatrin, 113 Brodie, 1993, Drugs in focus: 10 lamotrigine, Prescriber's Journal, 33, 212 Leppik, 1994, Lamotrigine, 91 Ferrie, 1994, Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy, Seizure, 3, 157, 10.1016/S1059-1311(05)80208-0 Palmer, 1993, Felbamate: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy, Drugs, 45, 1041, 10.2165/00003495-199345060-00008 Coulter, 1989, Specific petit mal anticonvulsants reduce calcium currents in thalamic neurones, Neurosci Lett, 98, 74, 10.1016/0304-3940(89)90376-5 Taylor, 1993, Mechanism of action of new anti-epileptic drugs, 41 MacDonald, 1994, Mechanism of action of new anticonvulsant drugs, 35 Fink Jensen, 1992, The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats, Eur J Pharmacol, 220, 197, 10.1016/0014-2999(92)90748-S Brodie, 1995, Tiagabine pharmacology in profile, Epilepsia, 36, 7, 10.1111/j.1528-1157.1995.tb06015.x McLean, 1994, Oxcarbazepine: mechanisms of action, Epilepsia, 35, 55, 10.1111/j.1528-1157.1994.tb05949.x Shank, 1994, Topiramate: preclinical evaluation of a structurally novel anticonvulsant, Epilepsia, 35, 450, 10.1111/j.1528-1157.1994.tb02459.x Brodie, 1995, Double blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy, Lancet, 345, 476, 10.1016/S0140-6736(95)90581-2 Kalviainen, 1995, Vigabatrin versus carbamazepine monotherapy in patients with newly diagnosed epilepsy: a randomised controlled study, Arch Neurol, 52, 989, 10.1001/archneur.1995.00540340081016 Marson, 1997, The new antiepileptic drugs: a systematic review of their efficacy and tolerability, Epilepsia, 10.1111/j.1528-1157.1997.tb01251.x Ferrie, 1996, Psychotic and severe behavioural reactions with vigabatrin: a review, Acta Neurol Scand, 93, 1, 10.1111/j.1600-0404.1996.tb00161.x Chadwick, 1994, Gabapentin, 75 Shorvon, 1996, Safety of topiramate: adverse events and relationship to dosing, Epilepsia, 37, 18, 10.1111/j.1528-1157.1996.tb06029.x 1996, 473 Yerby, 1991, Pregnancy and teratogenesis, 167 Richens, 1993, Clinical pharmacokinetics of gabapentin, 13 Walker, 1995, Clinical pharmacokinetics of new antiepileptic drugs, Pharmacol Ther, 67, 351, 10.1016/0163-7258(95)00021-6 Mawer, 1995, Interactions involving new antiepileptic drugs, Pharmacol Ther, 68, 209, 10.1016/0163-7258(95)02006-3 Scheuer, 1992, Medical aspects of treating epilepsy, 127 Wolf, 1992, Lamotrigine: preliminary clinical observations on pharmacokinetics and interactions with traditional antiepileptic drugs, J Epilepsy, 5, 73, 10.1016/S0896-6974(05)80054-4 Wilensky, 1989, Topiramate pharmacokinetics in epileptic patients receiving carbamazepine, Epilepsia, 30, 645 Floren, 1989, Pharmacokinetics of topiramate in patients with partial epilepsy receiving phenytoin or valproic acid, Epilepsia, 30, 646 Patsalos P N, Duncan J S. New antiepileptic drugs. A review of their current clinical status and clinical potential. CNS Drugs; 2: 40–77. Wong, 1996, Survey of the perceived efficacy and adverse reaction profiles of gabapentin, lamotrigine, vigabatrin, Epilepsia, 37, 80 Omtzigt, 1992, The risk of spina bifida aperta after first trimester exposure to valproate in a prenatal cohort, Neurology, 42, 119 1996, 378