Neutrophils in rheumatoid arthritis: More than simple final effectors

Nathan, 2006, Neutrophils and immunity: challenges and opportunities, Nat Rev Immunol, 6, 173, 10.1038/nri1785

Ashcroft, 2000, Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing, Nat Med, 6, 1147, 10.1038/80489

Cross, 2004, Secretion of oncostatin M by neutrophils in rheumatoid arthritis, Arthritis Rheum, 50, 1430, 10.1002/art.20166

Auer, 2007, Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis, Arthritis Res Ther, 9, R94, 10.1186/ar2294

Kasama, 2000, Expression of vascular endothelial growth factor by synovial fluid neutrophils in rheumatoid arthritis (RA), Clin Exp Immunol, 121, 533, 10.1046/j.1365-2249.2000.01272.x

Cheema, 2001, Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases, Arthritis Rheum, 44, 1313, 10.1002/1529-0131(200106)44:6<1313::AID-ART223>3.0.CO;2-S

Scapini, 2005, Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases, Blood, 105, 830, 10.1182/blood-2004-02-0564

Assi, 2007, Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint, Arthritis Rheum, 56, 1776, 10.1002/art.22697

Vossenaar, 2003, Citrullination of synovial proteins in murine models of rheumatoid arthritis, Arthritis Rheum, 48, 2489, 10.1002/art.11229

Eyles, 2006, Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease, Nat Clin Pract Rheumatol, 2, 500, 10.1038/ncprheum0291

Anzilotti, 2010, Peptidylarginine deiminase 4 and citrullination in health and disease, Autoimmun Rev, 9, 158, 10.1016/j.autrev.2009.06.002

Hoshino, 2008, MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner, J Autoimmun, 31, 79, 10.1016/j.jaut.2008.03.006

Bjorkman, 2008, Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease, Arthritis Rheum, 58, 2931, 10.1002/art.23941

Hultqvist, 2005, Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice, Cell Immunol, 233, 97, 10.1016/j.cellimm.2005.04.008

Bylund, 2007, Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B, Eur J Immunol, 37, 1087, 10.1002/eji.200636651

Kitas, 1988, T-cell functional defects in rheumatoid arthritis: intrinsic or extrinsic?, J Autoimmun, 1, 339, 10.1016/0896-8411(88)90004-2

Cedergren, 2007, Intracellular oxidative activation in synovial fluid neutrophils from patients with rheumatoid arthritis but not from other arthritis patients, J Rheumatol, 34, 2162

Robinson, 1992, Stimulation of neutrophils by insoluble immunoglobulin aggregates from synovial fluid of patients with rheumatoid arthritis, Eur J Clin Invest, 22, 314, 10.1111/j.1365-2362.1992.tb01468.x

Krumbholz, 2005, BAFF is elevated in serum of patients with Wegener's granulomatosis, J Autoimmun, 25, 298, 10.1016/j.jaut.2005.08.004

Bostan, 2001, Effects of synovial fluid on the respiratory burst of granulocytes in rheumatoid arthritis, J Cell Mol Med, 5, 188, 10.1111/j.1582-4934.2001.tb00152.x

Akgul, 2001, Molecular control of neutrophil apoptosis, FEBS Lett, 487, 318, 10.1016/S0014-5793(00)02324-3

Sweeney, 2004, Rheumatoid arthritis: regulation of synovial inflammation, Int J Biochem Cell Biol, 36, 372, 10.1016/S1357-2725(03)00259-0

Andersson, 2008, Recent developments in the immunobiology of rheumatoid arthritis, Arthritis Res Ther, 10, 204, 10.1186/ar2370

Weinmann, 2007, Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy, Clin Exp Rheumatol, 25, 885

Raza, 2006, Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis, Arthritis Res Ther, 8, R120, 10.1186/ar2009

Mangan, 2006, Transforming growth factor-beta induces development of the T(H)17 lineage, Nature, 441, 231, 10.1038/nature04754

Miranda-Carus, 2006, Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes, Arthritis Rheum, 54, 1151, 10.1002/art.21731

Rouse, 2007, Regulatory T cells in health and disease, J Intern Med, 262, 78, 10.1111/j.1365-2796.2007.01836.x

Renshaw, 2000, Inflammatory neutrophils retain susceptibility to apoptosis mediated via the Fas death receptor, J Leukoc Biol, 67, 662, 10.1002/jlb.67.5.662

Kiener, 1997, Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation, J Immunol, 159, 1594, 10.4049/jimmunol.159.4.1594

Hasunuma, 1997, Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis, Arthritis Rheum, 40, 80, 10.1002/art.1780400112

Bell, 1995, Human blood and synovial fluid neutrophils cultured in vitro undergo programmed cell death which is promoted by the addition of synovial fluid, Ann Rheum Dis, 54, 910, 10.1136/ard.54.11.910

Parsonage, 2008, Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha, Arthritis Res Ther, 10, R47, 10.1186/ar2406

Cross, 2006, Neutrophil apoptosis in rheumatoid arthritis is regulated by local oxygen tensions within joints, J Leukoc Biol, 80, 521, 10.1189/jlb.0306178

Wong, 2009, Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid, Rheumatology (Oxford), 48, 39, 10.1093/rheumatology/ken412

Iking-Konert, 2005, Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells, Ann Rheum Dis, 64, 1436, 10.1136/ard.2004.034132

Iking-Konert, 2002, Up-regulation of the dendritic cell marker CD83 on polymorphonuclear neutrophils (PMN): divergent expression in acute bacterial infections and chronic inflammatory disease, Clin Exp Immunol, 130, 501, 10.1046/j.1365-2249.2002.02008.x

Ziolkowska, 2002, High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment, Arthritis Rheum, 46, 1744, 10.1002/art.10388

Pettit, 2001, TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis, Am J Pathol, 159, 1689, 10.1016/S0002-9440(10)63016-7

Poubelle, 2007, Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils, Arthritis Res Ther, 9, R25, 10.1186/ar2137