Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

M Geiszt, 2001, Chronic granulomatous disease: more than the lack of superoxide?, J Leukoc Biol, 69, 191, 10.1189/jlb.69.2.191

C Nathan, 2006, Neutrophils and immunity: challenges and opportunities., Nat Rev Immunol, 6, 173, 10.1038/nri1785

V Brinkmann, 2004, Neutrophil extracellular traps kill bacteria., Science, 303, 1532, 10.1126/science.1092385

M von Kockritz-Blickwede, 2008, Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation., Blood, 111, 3070, 10.1182/blood-2007-07-104018

S Yousefi, 2008, Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense., Nat Med, 14, 949, 10.1038/nm.1855

TA Fuchs, 2007, Novel cell death program leads to neutrophil extracellular traps., J Cell Biol, 176, 231, 10.1083/jcb.200606027

AS Alghamdi, 2005, Seminal DNase frees spermatozoa entangled in neutrophil extracellular traps., Biol Reprod, 73, 1174, 10.1095/biolreprod.105.045666

JD Lippolis, 2006, Neutrophil extracellular trap formation by bovine neutrophils is not inhibited by milk., Vet Immunol Immunopathol, 113, 248, 10.1016/j.vetimm.2006.05.004

D Palic, 2007, Fish cast NETs: neutrophil extracellular traps are released from fish neutrophils., Dev Comp Immunol, 31, 805, 10.1016/j.dci.2006.11.010

K Beiter, 2006, An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps., Curr Biol, 16, 401, 10.1016/j.cub.2006.01.056

JT Buchanan, 2006, DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps., Curr Biol, 16, 396, 10.1016/j.cub.2005.12.039

SR Clark, 2007, Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood., Nat Med, 13, 463, 10.1038/nm1565

CF Urban, 2006, Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms., Cell Microbiol, 8, 668, 10.1111/j.1462-5822.2005.00659.x

AB Guimaraes-Costa, 2009, Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps., Proc Natl Acad Sci U S A, 106, 6748, 10.1073/pnas.0900226106

HH Gadebusch, 1966, Natural host resistance to infection with Cryptococcus neoformans. IV. The effect of some cationic proteins on the experimental disease., J Infect Dis, 116, 551, 10.1093/infdis/116.5.551

M Kashima, 1991, H1 histones contribute to candidacidal activities of human epidermal extract., J Dermatol, 18, 695, 10.1111/j.1346-8138.1991.tb03160.x

PS Hiemstra, 1993, Antimicrobial proteins of murine macrophages., Infect Immun, 61, 3038, 10.1128/IAI.61.7.3038-3046.1993

RA Hajjeh, 2004, Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program., J Clin Microbiol, 42, 1519, 10.1128/JCM.42.4.1519-1527.2004

FC Odds, 1987, Candida infections: an overview., Crit Rev Microbiol, 15, 1, 10.3109/10408418709104444

M Whiteway, 2007, Morphogenesis in Candida albicans., Annu Rev Microbiol, 61, 529, 10.1146/annurev.micro.61.080706.093341

F Cottier, 2009, Sensing the environment: response of Candida albicans to the X factor., FEMS Microbiol Lett, 295, 1, 10.1111/j.1574-6968.2009.01564.x

RA Calderone, 2001, Virulence factors of Candida albicans., Trends Microbiol, 9, 327, 10.1016/S0966-842X(01)02094-7

P Sudbery, 2004, The distinct morphogenic states of Candida albicans., Trends Microbiol, 12, 317, 10.1016/j.tim.2004.05.008

MP McNamara, 1988, Neutrophil death as a defence mechanism against Candida albicans infections., Lancet, 2, 1163, 10.1016/S0140-6736(88)90234-6

M Steinbakk, 1990, Antimicrobial actions of calcium binding leucocyte L1 protein, calprotectin., Lancet, 336, 763, 10.1016/0140-6736(90)93237-J

AR Murthy, 1993, In vitro candidastatic properties of the human neutrophil calprotectin complex., J Immunol, 151, 6291, 10.4049/jimmunol.151.11.6291

D Foell, 2007, S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules., J Leukoc Biol, 81, 28, 10.1189/jlb.0306170

D Foell, 2004, Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation., Clin Chim Acta, 344, 37, 10.1016/j.cccn.2004.02.023

PG Sohnle, 1991, The zinc-reversible antimicrobial activity of neutrophil lysates and abscess fluid supernatants., J Infect Dis, 164, 137, 10.1093/infdis/164.1.137

PG Sohnle, 1996, Inhibition of Candida albicans growth by calprotectin in the absence of direct contact with the organisms., J Infect Dis, 174, 1369, 10.1093/infdis/174.6.1369

BD Corbin, 2008, Metal chelation and inhibition of bacterial growth in tissue abscesses., Science, 319, 962, 10.1126/science.1152449

ED Weinberg, 1975, Nutritional immunity. Host's attempt to withold iron from microbial invaders., JAMA, 231, 39, 10.1001/jama.1975.03240130021018

HY Sroussi, 2009, Substitution of methionine 63 or 83 in S100A9 and cysteine 42 in S100A8 abrogate the antifungal activities of S100A8/A9: potential role for oxidative regulation., FEMS Immunol Med Microbiol, 55, 55, 10.1111/j.1574-695X.2008.00498.x

JM Ehrchen, 2009, The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer., J Leukoc Biol

T Vogl, 2007, Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock., Nat Med, 13, 1042, 10.1038/nm1638

A Rammes, 1997, Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway., J Biol Chem, 272, 9496, 10.1074/jbc.272.14.9496

K Kessenbrock, 2009, Netting neutrophils in autoimmune small-vessel vasculitis., Nat Med, 15, 623, 10.1038/nm.1959

S Jaillon, 2007, The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps., J Exp Med, 204, 793, 10.1084/jem.20061301

X Lauth, 2009, M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition., J Innate Immun, 1, 202, 10.1159/000203645

BJ Bentwood, 1980, The sequential release of granule constitutents from human neutrophils., J Immunol, 124, 855, 10.4049/jimmunol.124.2.855

K Luger, 1997, Crystal structure of the nucleosome core particle at 2.8 A resolution., Nature, 389, 251, 10.1038/38444

RI Lehrer, 1993, Holocrine secretion of calprotectin: a neutrophil-mediated defense against Candida albicans?, J Lab Clin Med, 121, 193

BE Steinberg, 2007, Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death., Sci STKE, 2007, pe11, 10.1126/stke.3792007pe11

RS Bhardwaj, 1992, The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions., Eur J Immunol, 22, 1891, 10.1002/eji.1830220732

M Bianchi, 2009, Restoration of NET formation by gene therapy in CGD controls aspergillosis., Blood

T Meshulam, 1995, A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanil ide (XTT)., J Infect Dis, 172, 1153, 10.1093/infdis/172.4.1153

MP Manitz, 2003, Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro., Mol Cell Biol, 23, 1034, 10.1128/MCB.23.3.1034-1043.2003

I Neeli, 2008, Histone deimination as a response to inflammatory stimuli in neutrophils., J Immunol, 180, 1895, 10.4049/jimmunol.180.3.1895

R Lopez-Alemany, 2003, Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase., Am J Hematol, 72, 234, 10.1002/ajh.10299

C Kerkhoff, 1999, The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils., J Biol Chem, 274, 32672, 10.1074/jbc.274.46.32672

A Voganatsi, 2001, Mechanism of extracellular release of human neutrophil calprotectin complex., J Leukoc Biol, 70, 130, 10.1189/jlb.70.1.130

D Ermert, 2009, Mouse Neutrophil Extracellular Traps in Microbial Infections., J Innate Immun, 1, 181, 10.1159/000205281

MK Fagerhol, 1980, Release and Quantitation of a Leucocyte Derived Protein (L1)., Scandinavian Journal of Haematology, 24, 393, 10.1111/j.1600-0609.1980.tb02754.x

J Edgeworth, 1991, Identification of p8,14 as a highly abundant heterodimeric calcium binding protein complex of myeloid cells., J Biol Chem, 266, 7706, 10.1016/S0021-9258(20)89506-4

SS Mambula, 2000, Human neutrophil-mediated nonoxidative antifungal activity against Cryptococcus neoformans., Infect Immun, 68, 6257, 10.1128/IAI.68.11.6257-6264.2000

RD Diamond, 1980, Damage to Candida albicans hyphae and pseudohyphae by the myeloperoxidase system and oxidative products of neutrophil metabolism in vitro., J Clin Invest, 66, 908, 10.1172/JCI109958

L Christin, 1997, Mechanisms and target sites of damage in killing of Candida albicans hyphae by human polymorphonuclear neutrophils., J Infect Dis, 176, 1567, 10.1086/514156

M Lackmann, 1992, Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins., J Biol Chem, 267, 7499, 10.1016/S0021-9258(18)42545-8

C Kerkhoff, 2005, The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2., FASEB J, 19, 467, 10.1096/fj.04-2377fje

D Viemann, 2007, MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program., Blood, 109, 2453, 10.1182/blood-2006-08-040444

JR Allport, 2002, Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro., J Leukoc Biol, 71, 821, 10.1189/jlb.71.5.821

AM Gillum, 1984, Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations., Mol Gen Genet, 198, 179, 10.1007/BF00328721

U Zimny-Arndt, 2009, Classical proteomics: two-dimensional electrophoresis/MALDI mass spectrometry., Methods Mol Biol, 492, 65, 10.1007/978-1-59745-493-3_4

F Schmidt, 2006, Distinctive mass losses of tryptic peptides generated by matrix-assisted laser desorption/ionization time-of-flight/time-of-flight., Rapid Commun Mass Spectrom, 20, 933, 10.1002/rcm.2382

S Takamori, 2006, Molecular anatomy of a trafficking organelle., Cell, 127, 831, 10.1016/j.cell.2006.10.030

M Klempt, 1997, The heterodimer of the Ca2+-binding proteins MRP8 and MRP14 binds to arachidonic acid., FEBS Lett, 408, 81, 10.1016/S0014-5793(97)00394-3

C Legrand, 1992, Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]., J Biotechnol, 25, 231, 10.1016/0168-1656(92)90158-6

M Allen, 1994, Lactate dehydrogenase activity as a rapid and sensitive test for the quantification of cell numbers in vitro., Clin Mater, 16, 189, 10.1016/0267-6605(94)90116-3