Neurotrophic factors and neural grafts: a growing field

Forno, 1990, Pathology of Parkinson's disease; the importance of the substantia nigra and Lewy bodies, 185 Martin, 1986, Huntington's disease. Pathogenesis and management, New Engl J Med, 315, 1267, 10.1056/NEJM198611133152006 Pearson, 1989, The neuroanatomy of Alzheimer's disease, Rev Neurosci, 2, 101, 10.1515/REVNEURO.1989.2.2.101 Mitsumoto, 1988, Amyotrophic lateral sclerosis. Recent advances in pathogenesis and therapeutic trials, Arch Neurol, 45, 189, 10.1001/archneur.1988.00520260077025 1993, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes, Cell, 72, 971, 10.1016/0092-8674(93)90585-E Wictorin, 1992, Anatomy and connectivity of intrastriatal striatal transplants, Prog Neurobiol, 38, 611, 10.1016/0301-0082(92)90044-F Dunnett, 1993, Huntington's disease: animal models and transplantation repair, Curr Opin Neuriobiol, 10.1016/0959-4388(93)90155-R Björklund, 1992, Dopaminergic transplants in experimental parkinsonism: cellular mechanisms of graft induced functional recovery, Curr Opin Neurobiol, 2, 683, 10.1016/0959-4388(92)90039-N Barde, 1988, What, if anything, is a neurotrophic factor?, Trends Neurosci, 11, 343, 10.1016/0166-2236(88)90055-0 Thoenen, 1991, The changing scene of neurotrophic factors, Trends Neurosci, 14, 165, 10.1016/0166-2236(91)90097-E Appel, 1981, A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism and Alzheimer's disease, Ann Neurol, 10, 499, 10.1002/ana.410100602 Clough, 1991, Parkinson's disease: management, Lancet, 337, 1324, 10.1016/0140-6736(91)92990-J Barker, 1993, The biology and behaviour of intracerebral adrenal transplants in animals and man, Rev Neurosci, 4, 113, 10.1515/REVNEURO.1993.4.2.113 Freed, 1991, Substantia nigra grafts and Parkinson's disease: from animal experiments to human therapeutic trials, Restor Neurol Neurosci, 3, 109 Verhofstad, 1985, Immunohistochemical and biochemical study on the noradrenaline and adrenaline storing cells of the adrenal medulla of the rat, Cell Tiss Res, 242, 233, 10.1007/BF00214536 Müller, 1981, High performance liquid chromatography with electrochemical detection as a highly efficient tool ofr studying catecholaminergic systems I. Quantification of noradrenaline, adrenaline and dopamine in cultured adrenal medullary cells, J Neurosci Methods, 4, 39, 10.1016/0165-0270(81)90017-0 Freed, 1983, Catecholamine content of intracerebral adrenal medulla grafts, Brain Res, 269, 184, 10.1016/0006-8993(83)90980-0 Becker, 1992, Adrenal medulla grafts in hemiparkinsonian rats: mechanisms mediating recovery of function, Restor Neurol Neurosci, 4, 174 Madrazo, 1987, Open microsurgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson's disease, N Engl J Med, 316, 831, 10.1056/NEJM198704023161402 Goetz, 1992, United Parkinson Foundation Neurotransplantation registry on adrenal medullary transplants: presurgical and 1 and 2 year follow up, Neurology, 41, 1719, 10.1212/WNL.41.11.1719 Sawle, 1993, The role of positron emission tomography in the assessment of human neurotransplantation, Trends Neurosci, 16, 172, 10.1016/0166-2236(93)90143-A Freed, 1980, Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: long term behavioral, biochemical and histochemical studies, Ann Neurol, 8, 510, 10.1002/ana.410080508 Bolam, 1987, Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum, Exp Brain Res, 68, 131, 10.1007/BF00255240 Freund, 1985, Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study, J Neurosci, 5, 603, 10.1523/JNEUROSCI.05-03-00603.1985 Dunnett, 1981, Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway, Brain Res, 229, 209, 10.1016/0006-8993(81)90759-9 Dunnett, 1988, Graft derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic tissues, Exp Brain Res, 71, 411, 10.1007/BF00247501 Fahn, 1992, Fetal tissue transplants in Parkinson's disease, N Engl J Med, 327, 1589, 10.1056/NEJM199211263272209 Doupe, 1985, Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors and chromaffin cell plasticity, J Neurosci, 5, 2119, 10.1523/JNEUROSCI.05-08-02119.1985 Doupe, 1985, Small intensely fluorescent cell in culture: role of glucocorticoids and growth factors in their development and interconversions with other neural crest derivatives, J Neurosci, 5, 2143, 10.1523/JNEUROSCI.05-08-02143.1985 Stromberg, 1985, Nerve fibre production by intraocular adrenal medullary grafts: stimulation by nerve growth factor or by sympathetic denervation of the host iris, Cell Tiss Res, 241, 241, 10.1007/BF00217167 Stromberg, 1985, Chronic implants of chromaffin tissue into the dopamine denervated striatum. Effects of NGF on graft survival, fiber outgrowth and rotational behavior, Exp Brain Res, 60, 335, 10.1007/BF00235929 Cunningham, 1991, The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted to the striatum, Brain Res, 561, 192, 10.1016/0006-8993(91)91595-R Doering, 1992, Peripheral nerve segments promote consistent long-term survival of adrenal medulla transplants in the brain, Exp Neurol, 118, 253, 10.1016/0014-4886(92)90182-P Watts, 1992, Early experience with intrastriatal adrenal medulla/nerve cografting in Parkinson's disease, Restor Neurol Neurosci, 4, 194 Olson, 1992, Intraputamenal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease, Restor Neurol Neurosci, 4, 194 Barid, 1993, Fibroblast growth factors: what's in a name?, Endocrinol, 132, 487, 10.1210/en.132.2.487 Bean, 1991, Expression of acidic and basic fibroblast growth factors in the substantia nigra of rat, monkey and human, 88, 10237 Tooyama, 1993, Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease, Neurology, 43, 372, 10.1212/WNL.43.2.372 Ferrari, 1989, Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture, Dev Biol, 133, 140, 10.1016/0012-1606(89)90305-9 Engele, 1991, The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia, J Neurosci, 11, 3070, 10.1523/JNEUROSCI.11-10-03070.1991 Mayer, 1993, Mitogenic effects of bFGF on embryonic mesencephalic dopaminergic neurones, Dev Brain Res, 72, 253, 10.1016/0165-3806(93)90190-L Mayer, 1993, Basic FGF promotes the survival of embryonic mesencephalic dopaminergic neurones. I. Effects in vitro, Neurosci Patel, 1992, Organisation of septohippocampal neurons and their regulation by trophic factors produced by astrocytes, 59 Lin, 1993, GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons, Science, 260, 1130, 10.1126/science.8493557 Steinbusch, 1990, Basic fibroblast growth factor enhances survival and sprouting of fetal dopaminergic cells implanted in the denervated rat caudate-putamen: preliminary observations, Prog Brain Res, 82, 81, 10.1016/S0079-6123(08)62593-5 Mayer, 1993, Basic FGF promotes the survival of embryonic ventral mesencephalic dopaminergic neurones. II. Effects on nigral transplants in vivo, Neurosci, 10.1016/0306-4522(93)90340-L Date, 1990, MPTP-treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (aFGF), Brain Res, 526, 156, 10.1016/0006-8993(90)90264-C Otto, 1990, Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice, J Neurosci, 10, 1912, 10.1523/JNEUROSCI.10-06-01912.1990 Park, 1992, Protection from 1-methyl-4-phenyl pyridium (MPP+) toxicity and stimulation of regrowth of MPP+-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF, Brain Res, 599, 83, 10.1016/0006-8993(92)90855-4 Meakin, 1992, The nerve growth factor family of receptors, Trends Neurosci, 15, 323, 10.1016/0166-2236(92)90047-C Gall, 1992, Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons, Mol Cell Neurosci, 3, 56, 10.1016/1044-7431(92)90009-Q Magal, 1991, Effect of CNTF on low affinity NGF receptor expression by cultured neurons from different rat brain regions, J Neurosci Res, 30, 560, 10.1002/jnr.490300314 Knüsel, 1991, Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3, 88, 961 Beck, 1993, The nature of the trophic action of brain-derived neurotrophic factor, des(1–3)-insulin-like growth factor-1 and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture, Neurosci, 52, 855, 10.1016/0306-4522(93)90534-M Spina, 1992, Brain derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridium ion toxicity: involvement of the glutathione system, J Neurochem, 59, 99, 10.1111/j.1471-4159.1992.tb08880.x Knüsel, 1992, Brain derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain, J Neurosci, 12, 4391, 10.1523/JNEUROSCI.12-11-04391.1992 Sauer, 1993, Brain derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts, Brain Res, 10.1016/0006-8993(93)90560-A Altar, 1992, Brain derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo, 89, 11347 Lapchak, 1993, Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection, Neurosci, 53, 639, 10.1016/0306-4522(93)90612-J Knüsel, 1990, Selective and non-selective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and insulin-like growth factors I and II, J Neurosci, 10, 558, 10.1523/JNEUROSCI.10-02-00558.1990 Brundin, 1985, Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival, Brain Res, 331, 251, 10.1016/0006-8993(85)91550-1 Pritzel, 1986, Afferent and efferent connections of striatal grafts implanted into ibotenic acid lesion striatum in adult rats, Exp Brain Res, 65, 112, 10.1007/BF00243834 Dunnett, 1988, Striatal grafts in the ibotenic acid-lesioned neostriatum: functional studies, Prog Brain Res, 78, 39, 10.1016/S0079-6123(08)60264-2 Matsuda, 1990, Effect of basis fibroblast growth factors on neurons cultured from various regions of postnatal rat brain, Brain Res, 520, 310, 10.1016/0006-8993(90)91720-2 Kessler, 1986, Differential regulation of cholinergic and peptidergic development in the rat striatum in culture, Dev Biol, 113, 77, 10.1016/0012-1606(86)90109-0 Okazawa, 1992, Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum, FEBS, 313, 138, 10.1016/0014-5793(92)81430-T Schumacher, 1991, Intracerebral implantation of nerve growth factor-producing fibroblasts protect striatum against neurotoxic levels of excitatory amino acids, Neurosci, 45, 561, 10.1016/0306-4522(91)90271-O Frim, 1993, Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions, NeuroReport, 4, 367, 10.1097/00001756-199304000-00006 Katzman, 1991, Advances in Alzheimer's disease, FASEB J, 5, 278, 10.1096/fasebj.5.3.2001787 Growdon, 1992, Treatment for Alzheimer's disease?, N Engl J Med, 327, 1306, 10.1056/NEJM199210293271810 Dunnett, 1992, The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions, Trends Neurosci, 14, 494, 10.1016/0166-2236(91)90061-X Dunnett, 1982, Septal transplants restore maze learning in rats with fimbria-fornix lesions, Brain Res, 251, 335, 10.1016/0006-8993(82)90751-X Nilsson, 1990, Acetylcholine release from intrahippocampal septal grafts is under control of the host brain, 87, 2647 Dunnett, 1991, Neural transplants as a treatment for Alzheimer's disease?, Psychol Med, 21, 825, 10.1017/S0033291700029822 Svendsen, 1993, NGF withdrawal results in the death of developing but not mature septal cholinergic neurons in vitro: protection by protein synthesis inhibition, J Neurosci Williams, 1986, Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria-fornix transection, 83, 9231 Tuszynski, 1991, Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain, Ann Neurol, 30, 625, 10.1002/ana.410300502 Fischer, 1987, Amelioration of cholinergic neuron atrophy and spatial memory in aged rat by nerve growth factor, Nature, 329, 65, 10.1038/329065a0 Tuszynski, 1990, Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection, Neurosci, 36, 33, 10.1016/0306-4522(90)90349-9 Gage, 1992, Neural transplants: prospects for Alzheimer's disease, Curr Opin Neurol Neurosurg, 5, 94 Strada, 1992, Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's Disease? An autoradiographic study in human striatum and basal forebrain, J Neurosci, 12, 4766, 10.1523/JNEUROSCI.12-12-04766.1992 Phillips, 1990, Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons, Science, 250, 290, 10.1126/science.1688328 Alderson, 1990, Brain derived neurotrophic factor increase survival and differentiated functions of rat septal cholinergic neurons in culture, Neuron, 5, 297, 10.1016/0896-6273(90)90166-D Thoenen, 1991, The synthesis of nerve growth factor and brain derived neurotrophic factor in hippocampal and cortical neurons is regulated by specific transmitter systems, Ann NY Acad Sci, 638, 86, 10.1111/j.1749-6632.1991.tb00196.x Lindefors, 1992, Septal cholinergic afferents regulate expression of brain derived neurotrophic factor and β-nerve growth factor mRNA in rat hippocampus, Exp Brain Res, 88, 78, 10.1007/BF02259130 Phillips, 1991, BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease, Neuron, 7, 695, 10.1016/0896-6273(91)90273-3 Lapchak, 1992, BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain, NeuroReport, 3, 405, 10.1097/00001756-199205000-00007 Widmer, 1993, BDNF protection of basal forebrain cholinergic neurons after axotomy: complete protection of p75 NGFR-positive cells, NeuroReport, 4, 363, 10.1097/00001756-199304000-00005 McNamara, 1993, Did radicals strike Lou Gehrig?, Nature, 362, 20, 10.1038/362020a0 Cadusseau, 1993, Development of motorneurons in spinal transplants, Restor Neurol Neurosci, 5, 61 Clowry, 1991, Grafts of embryonic tissue into spinal cord: a possible strategy for treating neuromuscular disorders, Neuromusc Disord, 1, 87, 10.1016/0960-8966(91)90054-V Kunkel-Bagden, 1990, Spinal cord transplants enhance the recovery of locomotor function after spinal cord injury at birth, Exp Brain Res, 81, 25, 10.1007/BF00230097 Lowrie, 1992, Dependence of postnatal motoneurones on their targets: review and hypothesis, Trends Neurosci, 15, 80, 10.1016/0166-2236(92)90014-Y Sieradzan, 1992, The ability of isolated embryonic motoneurones grafted into rat spinal cord to express cholinergic markers and innervate skeletal muscle, Restor Neurol Neurosci, 4, 220 Nothias, 1990, Double step neural transplants to replace degenerated motoneurons, Prog Brain Res, 82, 239, 10.1016/S0079-6123(08)62610-2 Oppenheim, 1992, High hopes of a trophic factor, Nature, 358, 451, 10.1038/358451a0 Yan, 1992, Brain derived neurotrophic factor rescues spinal motor neurons after axotomy-induced cell death, Nature, 360, 753, 10.1038/360753a0 Sendtner, 1992, Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section, Nature, 360, 757, 10.1038/360757a0 Arakawa, 1990, Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines, J Neurosci, 10, 3507, 10.1523/JNEUROSCI.10-11-03507.1990 Stöckli, 1989, Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor, Nature, 342, 920, 10.1038/342920a0 Gurney, 1992, Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor, J Neurosci, 12, 3241, 10.1523/JNEUROSCI.12-08-03241.1992 Patterson, 1993, Neuronal differentiation factors/cytokines and synaptic plasticity, Cell, 72, 123, 10.1016/S0092-8674(05)80032-7 Schwartz, 1992, Neurotransmitters as neurotrophic factors: a new set of functions, Int Rev Neurobiol, 34, 1, 10.1016/S0074-7742(08)60096-3 Hyman, 1991, BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra, Nature, 350, 230, 10.1038/350230a0 Leon, 1988, Development and survival of neurons in dissociated fetal mesencephalic serum-free cell cultures: II. Modulatory effects of gangliosides, J Neurosci, 8, 746, 10.1523/JNEUROSCI.08-03-00746.1988 Hama, 1991, Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures, Neurosci, 40, 445, 10.1016/0306-4522(91)90132-8 Nikkhah, 1993, Platelet derived growth factor promotes survival of rat and human mesencephalic neurons in culture, Exp Brain Res, 92, 516, 10.1007/BF00229041 Prochiantz, 1981, Specific stimulation of in vitro maturation of mesencephalic dopaminergic neurones by striatal membranes, Nature, 293, 570, 10.1038/293570a0 Dal Toso, 1988, Development and survival of neurons in dissociated mesencephalic serum-free cell cultures: I. Effects of cell density and of an adult mammalian striatal-derived neuronotrophic factor (SDNF), J Neurosci, 8, 733, 10.1523/JNEUROSCI.08-03-00733.1988 O'Malley, 1992, Mesencephalic type I astrocytes mediate the survival of substantia nigra dopaminergic neurons in culture, Brain Res, 582, 65, 10.1016/0006-8993(92)90317-3 Walicke, 1988, Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions, J Neurosci, 8, 2618, 10.1523/JNEUROSCI.08-07-02618.1988 Brenneman, 1992, Cytokine regulation of neuronal survival, J Neurochem, 38, 454, 10.1111/j.1471-4159.1992.tb09743.x Giacobini, 1991, Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts, Exp Brain Res, 86, 73, 10.1007/BF00231041 Hagg, 1992, Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS, Neuron, 8, 145, 10.1016/0896-6273(92)90116-U