Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates

Neuroscience - Tập 106 - Trang 669-677 - 2001
L Massieu1, P Del Rı́o1, T Montiel1
1Instituto de Fisiologı́a Celular, Departamento de Neurociencias, Universidad Nacional Autónoma de México, CP 04510 México D.F. AP 70-253, Mexico

Tài liệu tham khảo

Alston, 1977, 3-Nitropropionate, the substance of Indigofera, is a suicide inactivator of succinate dehydrogenase, Proc. Natl. Acad. Sci. USA, 74, 3767, 10.1073/pnas.74.9.3767 Baker, 1991, Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient flobal ischemia in the rabbit brain, J. Neurochem., 57, 1370, 10.1111/j.1471-4159.1991.tb08303.x Blitzblau, 1996, The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures, Eur. J. Neurosci., 8, 1840, 10.1111/j.1460-9568.1996.tb01328.x Brewer, 2000, Protective effect of the energy precursor creatine against toxicity of glutamate and β-amyloid in rat hippocampal neurons, J. Neurochem., 74, 1968, 10.1046/j.1471-4159.2000.0741968.x Bridges, 1991, Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer, J. Med. Chem., 34, 717, 10.1021/jm00106a037 Brouillet, 1998, Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat, J. Neurochem., 70, 794, 10.1046/j.1471-4159.1998.70020794.x Brustovetsky, 2001, On the mechanisms of neuroprotection by creatine and phosphocreatine, J. Neurochem., 76, 425, 10.1046/j.1471-4159.2001.00052.x Coyle, 1993, Oxidative stress, glutamate and neurodegenerative disorders, Science, 262, 689, 10.1126/science.7901908 Daikhin, 1998, Ketone bodies and brain glutamate and GABA metabolism, Dev. Neurosci., 20, 358, 10.1159/000017331 Desagher, 1997, Pyruvate protects neurons against hydrogen peroxide-induced toxicity, J. Neurosci., 17, 9060, 10.1523/JNEUROSCI.17-23-09060.1997 Desphande, 1997, 3-Nitropropionic acid increases the intracellular Ca2+ in cultured astrocytes by reverse operation of the Na+–Ca2+ exchanger, Exp. Neurol., 145, 38, 10.1006/exnr.1997.6457 Eimerl, 1995, Resuscitation of brain neurons in the presence of Ca2+ after toxic NMDA-receptor activity, J. Neurochem., 65, 739, 10.1046/j.1471-4159.1995.65020739.x Faden, 1989, The role of excitatory amino acids and NMDA receptors in traumatic brain injury, Science, 244, 798, 10.1126/science.2567056 Garcı́a, 2001, Strategies of neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro, J. Neurosci. Res., 64, 418, 10.1002/jnr.1093 Globus, 1988, Effect of ischemia on the release of striatal dopamine, glutamate, and γ-aminobutyric acid studied by intracerebral microdialysis, J. Neurochem., 51, 1455, 10.1111/j.1471-4159.1988.tb01111.x Hamilton, 1987, Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic (energy deficient) brain damage, Acta Neuropathol., 72, 286, 10.1007/BF00691103 Henneberry, 1989, The role of neuronal energy in the neurotoxicity of excitatory amino acids, Neurobiol. Aging, 10, 611, 10.1016/0197-4580(89)90149-8 Hodgkins, 1998, Interference with cellular energy metabolism reduces kynurenic acid formation in rat brain slices: reversal by lactate and pyruvate, Eur. J. Neurosci., 10, 1986, 10.1046/j.1460-9568.1998.00208.x Hodgkins, 1998, Metabolic control of kynurenic acid formation in the rat brain, Dev. Neurosci., 20, 408, 10.1159/000017338 Ikonomidou, 1995, Excitotoxicity and neurodegenerative diseases, Curr. Opin. Neurol., 8, 487, 10.1097/00019052-199512000-00017 Izumi, 1994, Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices, NeuroReport, 5, 617, 10.1097/00001756-199401000-00021 Izumi, 1997, Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation, J. Neurosci., 17, 9448, 10.1523/JNEUROSCI.17-24-09448.1997 Izumi, 1998, β-Hydroxybutyrate fuels synaptic function during development, J. Clin. Invest., 101, 1121, 10.1172/JCI1009 Kashiwaya, 2000, D-β-Hydroxybutyrate protects neurons in models of Alzheimer’s and Parkinson’s disease, Proc. Natl. Acad. Sci. USA, 97, 5440, 10.1073/pnas.97.10.5440 Kim, 2000, Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid, J. Cereb. Blood Flow Metab., 20, 119, 10.1097/00004647-200001000-00016 Malcon, 2000, Neuroprotective effects of creatine administration against NMDA and malonate toxicity, Brain Res., 860, 195, 10.1016/S0006-8993(00)02038-2 Massieu, 1997, Glutamate uptake impairment and neuronal damage in young and aged rats in vivo, J. Neurochem., 69, 1151, 10.1046/j.1471-4159.1997.69031151.x Massieu, 1995, Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study, J. Neurochem., 64, 2262, 10.1046/j.1471-4159.1995.64052262.x Massieu, 2000, In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate, Exp. Neurol., 165, 257, 10.1006/exnr.2000.7481 Matsumoto, 1993, Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia, J. Cereb. Blood Flow Metab., 13, 586, 10.1038/jcbfm.1993.76 Matthews, 1998, Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington’s disease, J. Neurosci., 18, 156, 10.1523/JNEUROSCI.18-01-00156.1998 Maus, 1999, Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity, Eur. J. Neurosci., 11, 3215, 10.1046/j.1460-9568.1999.00745.x Nehlig, 1993, Glucose and ketone body utilization by the brain of neonatal rats, Prog. Neurobiol., 40, 163, 10.1016/0301-0082(93)90022-K Novelli, 1988, Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced, Brain Res., 451, 205, 10.1016/0006-8993(88)90765-2 Obrenovitch, 1997, Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy, Prog. Neurobiol., 51, 39, 10.1016/S0301-0082(96)00049-4 Obrenovitch, 1993, Extracellular neuroactive amino acids in the rat striatum during ischemia: comparison between penumbral conditions and ischemia with sustained anoxic depolarisation, J. Neurochem., 61, 178, 10.1111/j.1471-4159.1993.tb03553.x O’Gorman, 1997, The role of creatine kinase in inhibition of mitochondrial permeability transition, FEBS Lett., 414, 253, 10.1016/S0014-5793(97)01045-4 Palmer, 1993, Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model, J. Neurochem., 61, 2015, 10.1111/j.1471-4159.1993.tb07437.x Pang, 1997, Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis, J. Neurosci., 17, 3064, 10.1523/JNEUROSCI.17-09-03064.1997 Paxinos, G., Watson, C., 1986. The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney. Pollay, 1980, Starvation-induced changes in transport of ketone bodies across the blood–brain barrier, J. Neurosci. Res., 5, 163, 10.1002/jnr.490050208 Rossi, 2000, Glutamate release in severe brain ischaemia is mainly by reversed uptake, Nature, 403, 316, 10.1038/35002090 Ruiz, 1998, Protection by pyruvate and malate against glutamate-mediated neurotoxicity, NeuroReport, 9, 1277 Sánchez-Carbente, 1999, Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired, J. Neurochem., 72, 129, 10.1046/j.1471-4159.1999.0720129.x Sandberg, 1986, Extracellular overflow of neuroactive amino acids during severe insulin-induced hypoglycemia: in vivo dialysis of the rat hippocampus, J. Neurochem., 47, 178, 10.1111/j.1471-4159.1986.tb02847.x Schinder, 1996, Mitochondrial dysfunction is a primary event in glutamate neurotoxicity, J. Neurosci., 16, 6125, 10.1523/JNEUROSCI.16-19-06125.1996 Schulz, 1996, Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases, Neuroscience, 71, 1043, 10.1016/0306-4522(95)00527-7 Schulz, 1996, Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity, Neurochem. Int., 29, 167, 10.1016/0197-0186(95)00122-0 Small, D.L., Morley, P., Buchan, A.M., 1997. Preclinical studies of glutamate receptor antagonists for the treatment of cerebral ischemia. In: Miller, L.P. (Ed.), Stroke Therapy. Basic, Preclinical, and Clinical Directions. Wiley-Liss, New York, pp. 65–99. Volterra, 1996, The competitive transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate triggers excitotoxicity in rat cortical neuron–astrocyte co-cultures via glutamate release rather than uptake inhibition, Eur. J. Neurosci., 8, 2019, 10.1111/j.1460-9568.1996.tb01345.x Wallimann, 1992, Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis, Biochem. J., 281, 21, 10.1042/bj2810021 Whal, 1994, Extracellular glutamate during focal cerebral ischaemia in rats: time course and calcium dependency, J. Neurochem., 63, 1003, 10.1046/j.1471-4159.1994.63031003.x Xu, 1997, Effect of phosphomonoesters, phosphodiesters, and phosphocreatine on glutamate uptake by synaptic vesicles, Mol. Chem. Neuropathol., 32, 89, 10.1007/BF02815169 Zeevalk, 1990, Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina, J. Pharmacol. Exp. Ther., 253, 1285 Zeevalk, 1992, Evidence that the loss of the voltage-dependent Mg2+ block at the N-methyl-D-aspartate receptor underlines receptor activation during inhibition of neuronal metabolism, J. Neurochem., 59, 1211, 10.1111/j.1471-4159.1992.tb08430.x