Neurotensin 1 receptor in the prelimbic cortex regulates anxiety-like behavior in rats

Buhler, 2005, Neurotensin activation of the NTR1 on spinally-projecting serotonergic neurons in the rostral ventromedial medulla is antinociceptive, Pain, 114, 285, 10.1016/j.pain.2004.12.031 Calhoon, 2015, Resolving the neural circuits of anxiety, Nat. Neurosci., 18, 1394, 10.1038/nn.4101 Carraway, 1973, The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami, J. Biol. Chem., 248, 6854, 10.1016/S0021-9258(19)43429-7 Deutch, 1987, Stress-induced alterations in neurotensin, somatostatin and corticotropin-releasing factor in mesotelencephalic dopamine system regions, Brain Res., 417, 350, 10.1016/0006-8993(87)90462-8 Ebner, 2004, Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats, Proc. Natl. Acad. Sci. U. S. A., 101, 4280, 10.1073/pnas.0400794101 Fitzpatrick, 2012, Altered sleep and affect in the neurotensin receptor 1 knockout mouse, Sleep, 35, 949, 10.5665/sleep.1958 Geisler, 2006, Brain neurotensin, psychostimulants, and stress - emphasis on neuroanatomical substrates, Peptides, 27, 2364, 10.1016/j.peptides.2006.03.037 Gross, 2004, The developmental origins of anxiety, Nat. Rev. Neurosci., 5, 545, 10.1038/nrn1429 Izaguirre, 2016, Elucidating the role of peripheral Neurotensin in appetite control, Endocrinology, 157, 3391, 10.1210/en.2016-1542 Kinkead, 2004, Neurotensin, schizophrenia, and antipsychotic drug action, Int. Rev. Neurobiol., 59, 327, 10.1016/S0074-7742(04)59013-X Kleczkowska, 2013, Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review, Eur. J. Pharmacol., 716, 54, 10.1016/j.ejphar.2013.03.004 Laszlo, 2010, The role of neurotensin in positive reinforcement in the rat central nucleus of amygdala, Behav. Brain Res., 208, 430, 10.1016/j.bbr.2009.12.022 Li, 2016, An obligatory role for neurotensin in high-fat-diet-induced obesity, Nature, 533, 411, 10.1038/nature17662 Lisboa, 2010, Different role of the ventral medial prefrontal cortex on modulation of innate and associative learned fear, Neuroscience, 171, 760, 10.1016/j.neuroscience.2010.09.048 Luttinger, 1982, The effect of neurotensin on food consumption in the rat, Eur. J. Pharmacol., 81, 499, 10.1016/0014-2999(82)90116-9 Maaswinkel, 1996, Effects of an electrolytic lesion of the prelimbic area on anxiety-related and cognitive tasks in the rat, Behav. Brain Res., 79, 51, 10.1016/0166-4328(95)00261-8 Mendez, 1997, High affinity neurotensin receptor mRNA distribution in rat brain and peripheral tissues. Analysis by quantitative RT-PCR, J. Mol. Neurosci., 9, 93, 10.1007/BF02736853 Moghaddam, 2002, Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders, Biol. Psychiatry, 51, 775, 10.1016/S0006-3223(01)01362-2 Normandeau, 2018, A key role for Neurotensin in chronic-stress-induced anxiety-like behavior in rats, Neuropsychopharmacology, 43, 285, 10.1038/npp.2017.134 Ollmann, 2015, Positive reinforcing effect of neurotensin microinjection into the ventral pallidum in conditioned place preference test, Behav. Brain Res., 278, 470, 10.1016/j.bbr.2014.10.021 Ollmann, 2015, Anxiolytic effect of neurotensin microinjection into the ventral pallidum, Behav. Brain Res., 294, 208, 10.1016/j.bbr.2015.08.010 Paxinos, 2014 Pentkowski, 2013, Cortagine infused into the medial prefrontal cortex attenuates predator-induced defensive behaviors and Fos protein production in selective nuclei of the amygdala in male CD1 mice, Horm. Behav., 64, 519, 10.1016/j.yhbeh.2013.06.008 Petrie, 2004, The neurotensin agonist PD149163 increases Fos expression in the prefrontal cortex of the rat, Neuropsychopharmacology, 29, 1878, 10.1038/sj.npp.1300494 Prus, 2014, Acute, but not repeated, administration of the neurotensin NTS1 receptor agonist PD149163 decreases conditioned footshock-induced ultrasonic vocalizations in rats, Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 49, 78, 10.1016/j.pnpbp.2013.11.011 Sabihi, 2014, Oxytocin in the medial prefrontal cortex regulates maternal care, maternal aggression and anxiety during the postpartum period, Front. Behav. Neurosci., 8, 10.3389/fnbeh.2014.00258 Sabihi, 2014, Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats, Psychoneuroendocrinology, 45, 31, 10.1016/j.psyneuen.2014.03.009 Saitoh, 2014, Activation of the prelimbic medial prefrontal cortex induces anxiety-like behaviors via N-Methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in mice, J. Neurosci. Res., 92, 1044, 10.1002/jnr.23391 Saiz Ruiz, 1992, Plasma neuropeptides in affective and anxiety disorders, Arch. Neurobiol. (Madr.), 55, 1 Sanz, 1993, Effects of neurotensin on the release of glutamic acid in the prefrontal cortex and striatum of the rat, Neuroreport, 4, 1194 Shilling, 2008, The neurotensin-1 receptor agonist PD149163 blocks fear-potentiated startle, Pharmacol. Biochem. Behav., 90, 748, 10.1016/j.pbb.2008.05.025 Shugalev, 2012, Reproduction of passive avoidance reactions after Neurotensin microinjection into nucleus Accumbens of rat brain against the background of reserpine action, Zh Vyssh Nerv Deyat+, 62, 357 Sun, 2019, Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1, Mol. Psychiatry, 24, 126, 10.1038/s41380-018-0102-9 Swanson, 2005, Metabotropic glutamate receptors as novel targets for anxiety and stress disorders, Nat. Rev. Drug Discov., 4, 131, 10.1038/nrd1630 Torregrossa, 2008, Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement, J. Pharmacol. Exp. Ther., 325, 556, 10.1124/jpet.107.130310 Tschumi, 2019, Diverse actions of the modulatory peptide neurotensin on central synaptic transmission, Eur. J. Neurosci., 49, 784, 10.1111/ejn.13858 Vadnie, 2014, Activation of neurotensin receptor type 1 attenuates locomotor activity, Neuropharmacology, 85, 482, 10.1016/j.neuropharm.2014.05.046 Van Eden, 1985, Cytoarchitectonic development of the prefrontal cortex in the rat, J. Comp. Neurol., 241, 253, 10.1002/cne.902410302 Vincent, 1999, Neurotensin and neurotensin receptors, Trends Pharmacol. Sci., 20, 302, 10.1016/S0165-6147(99)01357-7 Wieronska, 2013, Glutamate-based anxiolytic ligands in clinical trials, Expert Opin. Investig. Drugs, 22, 1007, 10.1517/13543784.2013.803066