Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor
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Barbacid, 1995, Neurotrophic factors and their receptors, Curr. Opin. Cell Biol., 7, 148, 10.1016/0955-0674(95)80022-0
Barleon, 1996, Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1, Blood, 87, 3336, 10.1182/blood.V87.8.3336.bloodjournal8783336
Breier, 1992, Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation, Development, 114, 521, 10.1242/dev.114.2.521
Carmeliet, 1996, Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele, Nature, 380, 435, 10.1038/380435a0
Chen, 1997, Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III, Neuron, 19, 547, 10.1016/S0896-6273(00)80371-2
Cohen, 1992, High levels of biologically active vascular endothelial growth factor (VEGF) are produced by the baculovirus expression system, Growth Factors, 7, 131, 10.3109/08977199209046402
de Vries, 1992, The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor, Science, 255, 989, 10.1126/science.1312256
Dvorak, 1991, Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors, J. Exp. Med., 174, 1275, 10.1084/jem.174.5.1275
Dvorak, 1995, Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis, Am. J. Path., 146, 1029
Elenius, 1997, Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation, EMBO J., 16, 1268, 10.1093/emboj/16.6.1268
Enomoto, 1994, Vascular endothelial growth factor induces the disorganization of actin stress fibers accompanied by protein tyrosine phosphorylation and morphological change in Balb/C3T3 cells, Biochem. Biophys. Res. Commun., 202, 1716, 10.1006/bbrc.1994.2133
Feiner, 1997, Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ, Neuron, 19, 539, 10.1016/S0896-6273(00)80370-0
Ferrara, 1997, The biology of vascular endothelial growth factor, Endocrine Rev., 18, 4, 10.1210/edrv.18.1.0287
Ferrara, 1996, Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene, Nature, 380, 439, 10.1038/380439a0
Flamme, 1995, Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo, Dev. Biol., 169, 699, 10.1006/dbio.1995.1180
Fong, 1995, Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium, Nature, 376, 66, 10.1038/376066a0
Fujisawa, 1995, Growth-associated expression of a membrane protein, neuropilin, in Xenopus optic nerve fibers, Dev. Neurosci., 17, 343, 10.1159/000111304
Gearing, 1989, Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor, EMBO J., 8, 3667, 10.1002/j.1460-2075.1989.tb08541.x
Gitay-Goren, 1992, The binding of vascular endothelial growth factor to its receptors is dependent on cell surface–associated heparin-like molecules, J. Biol. Chem., 267, 6093, 10.1016/S0021-9258(18)42666-X
Gitay-Goren, 1996, Selective binding of VEGF121 to one of the three VEGF receptors of vascular endothelial cells, J. Biol. Chem., 267, 6093, 10.1016/S0021-9258(18)42666-X
He, 1997, Neuropilin is a receptor for the axonal chemorepellent Semaphorin III, Cell, 90, 739, 10.1016/S0092-8674(00)80534-6
Houck, 1992, Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms, J. Biol. Chem., 267, 26031, 10.1016/S0021-9258(18)35712-0
Joukov, 1996, A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases, EMBO J., 15, 1751, 10.1002/j.1460-2075.1996.tb00521.x
Kawakami, 1995, Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system, J. Neurobiol., 29, 1, 10.1002/(SICI)1097-4695(199601)29:1<1::AID-NEU1>3.0.CO;2-F
Keck, 1989, Vascular permeability factor, an endothelial cell mitogen related to PDGF, Science, 246, 1309, 10.1126/science.2479987
Kendall, 1993, Inhibition of vascular endothelial growth factor activity by endogenously encoded soluble receptor, Proc. Natl. Acad. Sci. USA, 90, 10705, 10.1073/pnas.90.22.10705
Keyt, 1996, Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis, J. Biol. Chem., 271, 5638, 10.1074/jbc.271.10.5638
Keyt, 1996, The carboxyl-terminal domain (111–165) of vascular endothelial growth factor is critical for its mitogenic potency, J. Biol. Chem., 271, 7788, 10.1074/jbc.271.13.7788
Kim, 1993, Inhibition of vascular endothelial growth factor–induced angiogenesis suppresses tumor growth in vivo, Nature, 362, 841, 10.1038/362841a0
Kitsukawa, 1995, Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs, Development, 121, 4309, 10.1242/dev.121.12.4309
Kitsukawa, 1997, Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice, Neuron, 19, 995, 10.1016/S0896-6273(00)80392-X
Klagsbrun, 1996, Vascular endothelial growth factor and its receptors, Cytokine Growth Factor Rev., 7, 259, 10.1016/S1359-6101(96)00027-5
Kolodkin, 1993, The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules, Cell, 75, 1389, 10.1016/0092-8674(93)90625-Z
Kolodkin, 1997, Neuropilin is a Semaphorin III receptor, Cell, 90, 753, 10.1016/S0092-8674(00)80535-8
Leung, 1989, Vascular endothelial growth factor is a secreted angiogenic mitogen, Science, 246, 1306, 10.1126/science.2479986
Lopez-Casillas, 1993, Betaglycan presents ligand to the TGFβ signaling receptor, Cell, 73, 1435, 10.1016/0092-8674(93)90368-Z
Midy, 1994, Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts, Biochem. Biophys. Res. Commun., 199, 380, 10.1006/bbrc.1994.1240
Millauer, 1993, High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis, Cell, 72, 835, 10.1016/0092-8674(93)90573-9
Millauer, 1994, Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant, Nature, 367, 576, 10.1038/367576a0
Omura, 1997, Identification of a 190-kDa vascular endothelial growth factor165 cell surface binding protein on human glioma cell line, J. Biol. Chem., 272, 23317, 10.1074/jbc.272.37.23317
Peters, 1993, Vascular endothelial growth factor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth, Proc. Natl. Acad. Sci. USA, 90, 8915, 10.1073/pnas.90.19.8915
Plate, 1992, Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo, Nature, 359, 845, 10.1038/359845a0
Plouet, 1989, Isolation and characterization of newly identified endothelial cell mitogen produced by AtT-20 cells, EMBO J., 8, 3801, 10.1002/j.1460-2075.1989.tb08557.x
Poltorak, 1997, VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix, J. Biol. Chem., 272, 7151, 10.1074/jbc.272.11.7151
Shalaby, 1995, Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice, Nature, 376, 62, 10.1038/376062a0
Shibuya, 1990, Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family, Oncogene, 5, 519
Shweiki, 1993, Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis, J. Clin. Invest., 91, 2235, 10.1172/JCI116450
Soker, 1996, Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain, J. Biol. Chem., 271, 5761, 10.1074/jbc.271.10.5761
Soker, 1997, Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165, J. Biol. Chem., 272, 31582, 10.1074/jbc.272.50.31582
Takagi, 1987, Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies, Dev. Biol., 122, 90, 10.1016/0012-1606(87)90335-6
Takagi, 1991, The A5 antigen, a candidate for the neural recognition molecule, has homologies to complement components and coagulation factors, Neuron, 7, 295, 10.1016/0896-6273(91)90268-5
Takagi, 1995, Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system, Dev. Biol., 170, 207, 10.1006/dbio.1995.1208
Terman, 1992, Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor, Biochem. Biophys. Res. Commun., 187, 1579, 10.1016/0006-291X(92)90483-2
Tischer, 1989, Vascular endothelial growth factor, Biochem. Biophys. Res. Commun., 165, 1198, 10.1016/0006-291X(89)92729-0
Tischer, 1991, The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing, J. Biol. Chem., 266, 11947, 10.1016/S0021-9258(18)99049-6
Waltenberger, 1994, Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor, J. Biol. Chem., 269, 26988, 10.1016/S0021-9258(18)47116-5
Wilchek, 1982, Immobilization of enzymes and affinity ligands onto agarose via stable and uncharged carbamate linkages, Biochem. Int., 4, 629
Yayon, 1991, Cell surface, heparin-like molecules are required for binding basic fibroblast growth factor to its high affinity receptors, Cell, 64, 841, 10.1016/0092-8674(91)90512-W