Neurons in Niemann-Pick Disease Type C Accumulate Gangliosides as Well as Unesterified Cholesterol and Undergo Dendritic and Axonal Alterations
Tóm tắt
Từ khóa
Tài liệu tham khảo
Siegel, 1994, Growth of ectopic dendrites on cortical pyramidal neurons in neuronal storage diseases correlates with abnormal accumulation of GM2 ganglioside, J Neurochem, 62, 1852, 10.1046/j.1471-4159.1994.62051852.x
Walkley, 1998, Cellular pathology of lysosomal storage disorders, Brain Pathology, 8, 175, 10.1111/j.1750-3639.1998.tb00144.x
Garver, 2000, Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments, J Lipid Res, 41, 673, 10.1016/S0022-2275(20)32376-2
Xie, 1999, Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein, Am J Physiol, 276, E336
Liu, 2000, Alleviation of neuronal ganglioside storage does no improve the clinical course of the Niemann-Pick C disease mouse, Human Mol Gen, 9, 1007, 10.1093/hmg/9.7.1087
Kolter, 1998, Recent advances in the biochemistry of sphingolipidoses, Brain Path, 8, 79, 10.1111/j.1750-3639.1998.tb00138.x
Zervas, 2000, GM2 ganglioside and pyramidal neuron dendritogenesis in cultures from ferret cerebral cortex (Abstract), Soc Neurosci, 26, 572
Hakomori, 1990, Bifunctional role of glycosphingolipids, J Biol Chem, 265, 18713, 10.1016/S0021-9258(17)30565-3
Hakomori S . Role of gangliosides in transmembrane signaling and cell recognition. In: Rosengerg A , ed. Biology of the sialic acids. New York: Plenum Press, 1995:243–57
Carlson, 1988, Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2, major sialoglycoproteins carrying polylactosaminoglycan, J Biol Chem, 263, 18911, 10.1016/S0021-9258(18)37369-1
Zervas, 1999, Species differences in the degree of ectopic dendritogenesis on cortical pyramidal neurons on neuronal storage diseases (Abstract), Soc Neurosci, 25, 1117
Sonderfeld, 1985, Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects, Eur J Biochem, 149, 247, 10.1111/j.1432-1033.1985.tb08919.x
Schwarzmann, 1990, Metabolism and intracellular transport of glycosphingolipids, Perspectives in Biochemistry, 29, 10865, 10.1021/bi00501a001
Trinchera, 1990, Precursor-product relationship between GM1 and GD1a biosynthesized from exogenous GM2 ganglioside in rat liver, J Biochem, 107, 619, 10.1093/oxfordjournals.jbchem.a123096
Leppimaki, 1998, The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts, Biochem J, 338, 285, 10.1042/bj3350285
Overly, 1996, Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons, J Neurosci, 16, 6056, 10.1523/JNEUROSCI.16-19-06056.1996
Franklin KBJ Paxinos G . The mouse brain in stereotaxic coordinates. San Diego: Academic Press, 1997