Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion

Du, 2017, Molecular mechanisms of vascular dementia: What can be learned from animal models of chronic cerebral hypoperfusion?, Mol Neurobiol, 54, 3670, 10.1007/s12035-016-9915-1 Gorelick, 2011, Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American Stroke Association, Stroke, 42, 2672, 10.1161/STR.0b013e3182299496 Jia, 2020, Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: A cross-sectional study, Lancet Public Health, 5, e661, 10.1016/S2468-2667(20)30185-7 Jia, 2014, The prevalence of dementia in urban and rural areas of China, Alzheimers Dement, 10, 1, 10.1016/j.jalz.2013.01.012 Oberlin, 2017, Effects of physical activity on poststroke cognitive function: A meta-analysis of randomized controlled trials, Stroke, 48, 3093, 10.1161/STROKEAHA.117.017319 Shu, 2020, Cognitive gains of aerobic exercise in patients with ischemic cerebrovascular disorder: A systematic review and meta-analysis, Front Cell Dev Biol, 8, 582380, 10.3389/fcell.2020.582380 Liu-Ambrose, 2016, Aerobic exercise and vascular cognitive impairment: A randomized controlled trial, Neurology, 87, 2082, 10.1212/WNL.0000000000003332 Choi, 2016, Effect of exercise-induced neurogenesis on cognitive function deficit in a rat model of vascular dementia, Mol Med Rep, 13, 2981, 10.3892/mmr.2016.4891 Lee, 2018, Effect of treadmill exercise on spatial navigation impairment associated with cerebellar Purkinje cell loss following chronic cerebral hypoperfusion, Mol Med Rep, 17, 8121 Jia, 2021, Blood neuro-exosomal synaptic proteins predict Alzheimer's disease at the asymptomatic stage, Alzheimers Dement, 17, 49, 10.1002/alz.12166 Headley, 2018, Neurogranin as a predictor of memory and executive function decline in MCI patients, Neurology, 90, e887, 10.1212/WNL.0000000000005057 Kvartsberg, 2015, Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease, Alzheimers Dement, 11, 1180, 10.1016/j.jalz.2014.10.009 Liu, 2020, Neurogranin as a cognitive biomarker in cerebrospinal fluid and blood exosomes for Alzheimer's disease and mild cognitive impairment, Transl Psychiatry, 10, 125, 10.1038/s41398-020-0801-2 Janelidze, 2016, Cerebrospinal fluid neurogranin and YKL-40 as biomarkers of Alzheimer's disease, Ann Clin Transl Neurol, 3, 12, 10.1002/acn3.266 Willemse, 2018, Neurogranin as cerebrospinal fluid biomarker for Alzheimer disease: An assay comparison study, Clin Chem, 64, 927, 10.1373/clinchem.2017.283028 Casaletto, 2017, Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers, Neurology, 89, 1782, 10.1212/WNL.0000000000004569 Shibata, 2004, White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion, Stroke, 35, 2598, 10.1161/01.STR.0000143725.19053.60 Liu, 2018, Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins, J Affect Disord, 227, 126, 10.1016/j.jad.2017.10.019 Spowart-Manning, 2004, The T-maze continuous alternation task for assessing the effects of putative cognition enhancers in the mouse, Behav Brain Res, 151, 37, 10.1016/j.bbr.2003.08.004 Farkas, 2007, Permanent, bilateral common carotid artery occlusion in the rat: A model for chronic cerebral hypoperfusion-related neurodegenerative diseases, Brain Res Rev, 54, 162, 10.1016/j.brainresrev.2007.01.003 Lin, 2018, Genetic dissection of presynaptic and postsynaptic BDNF-TrkB signaling in synaptic efficacy of CA3-CA1 synapses, Cell Rep, 24, 1550, 10.1016/j.celrep.2018.07.020 Kalaria, 2016, Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease, Acta Neuropathol, 131, 659, 10.1007/s00401-016-1571-z Venkat, 2015, Models and mechanisms of vascular dementia, Exp Neurol, 272, 97, 10.1016/j.expneurol.2015.05.006 Nishio, 2010, A mouse model characterizing features of vascular dementia with hippocampal atrophy, Stroke, 41, 1278, 10.1161/STROKEAHA.110.581686 Song, 2019, Effect of regular swimming exercise to duration-intensity on neurocognitive function in cerebral infarction rat model, Neurol Res, 41, 37, 10.1080/01616412.2018.1524087 Moser, 2015, Place cells, grid cells, and memory, Cold Spring Harb Perspect Biol, 7, a021808, 10.1101/cshperspect.a021808 Sun, 2018, Astrocytes protect neurons in the hippocampal CA3 against ischemia by suppressing the intracellular Ca2+ overload, Front Cell Neurosci, 12, 280, 10.3389/fncel.2018.00280 Dupret, 2010, The reorganization and reactivation of hippocampal maps predict spatial memory performance, Nat Neurosci, 13, 995, 10.1038/nn.2599 Patten, 2015, The benefits of exercise on structural and functional plasticity in the rodent hippocampus of different disease models, Brain Plast, 1, 97, 10.3233/BPL-150016 Bocchio, 2017, Synaptic plasticity, engrams, and network oscillations in amygdala circuits for storage and retrieval of emotional memories, Neuron, 94, 731, 10.1016/j.neuron.2017.03.022 Lisman, 2018, Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability, Nat Neurosci, 21, 309, 10.1038/s41593-018-0076-6 Wu, 2017, Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP, Nature, 544, 316, 10.1038/nature21720 Foster, 2018, Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling, Sci Signal, 11, eaat9093, 10.1126/scisignal.aat9093 Yang, 2017, Gastrin-releasing peptide facilitates glutamatergic transmission in the hippocampus and effectively prevents vascular dementia induced cognitive and synaptic plasticity deficits, Exp Neurol, 287, 75, 10.1016/j.expneurol.2016.08.008 Bhuvanendran, 2019, Embelin Improves the spatial memory and hippocampal long-term potentiation in a rat model of chronic cerebral hypoperfusion, Sci Rep, 9, 14507, 10.1038/s41598-019-50954-y Pak, 2000, Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice, Proc Natl Acad Sci U S A, 97, 11232, 10.1073/pnas.210184697 Huang, 2006, Environmental enrichment enhances neurogranin expression and hippocampal learning and memory but fails to rescue the impairments of neurogranin null mutant mice, J Neurosci, 26, 6230, 10.1523/JNEUROSCI.1182-06.2006 Manniche, 2020, Cerebrospinal fluid biomarkers to differentiate idiopathic normal pressure hydrocephalus from subcortical ischemic vascular disease, J Alzheimers Dis, 75, 937, 10.3233/JAD-200036 Bloniecki, 2020, Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration?, Alzheimers Res Ther, 12, 153, 10.1186/s13195-020-00718-y De Vos, 2017, Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke, BMC Neurol, 17, 170, 10.1186/s12883-017-0945-8 Li, 2000, MAP2 and neurogranin as markers for dendritic lesions in CNS injury. An immunohistochemical study in the rat, APMIS, 108, 98, 10.1034/j.1600-0463.2000.d01-32.x Represa, 1990, Neurogranin immunocytochemical localization of a brain-specific protein kinase C substrate, J Neurosci, 10, 3782, 10.1523/JNEUROSCI.10-12-03782.1990 Garrido-García, 2019, Neurogranin expression is regulated by synaptic activity and promotes synaptogenesis in cultured hippocampal neurons, Mol Neurobiol, 56, 7321, 10.1007/s12035-019-1593-3 Wu, 2003, Participation of NMDA-mediated phosphorylation and oxidation of neurogranin in the regulation of Ca2+- and Ca2+/calmodulin-dependent neuronal signaling in the hippocampus, J Neurochem, 86, 1524, 10.1046/j.1471-4159.2003.01963.x Ataei, 2015, Calcium/calmodulin-dependent protein kinase II is a ubiquitous molecule in human long-term memory synaptic plasticity: A systematic review, Int J Prev Med, 6, 88, 10.4103/2008-7802.164831 Jones, 2018, Rapid, experience-dependent translation of neurogranin enables memory encoding, Proc Natl Acad Sci U S A, 115, E5805, 10.1073/pnas.1716750115 Li, 2012, Effects of rehabilitation on cognition, synaptophysin and neurogranin in rats with cerebral infarction, Chin J Rehabil Theory Pract, 18, 15 Lin, 2021, Involuntary, forced or voluntary exercise can ameliorate the cognitive deficits by enhancing levels of hippocampal NMDAR1, pAMPAR1 and pCaMKII in a model of vascular dementia, Neurol Res, 43, 349, 10.1080/01616412.2020.1866351 Luca, 2019, Oxidative stress-related endothelial damage in vascular depression and vascular cognitive impairment: Beneficial effects of aerobic physical exercise, Oxid Med Cell Longev, 2019, 8067045, 10.1155/2019/8067045 Trigiani, 2020, Benefits of physical exercise on cognition and glial white matter pathology in a mouse model of vascular cognitive impairment and dementia, GLIA, 68, 1925, 10.1002/glia.23815 Huang, 2011, Stimulation-mediated translocation of calmodulin and neurogranin from soma to dendrites of mouse hippocampal CA1 pyramidal neurons, Neuroscience, 178, 1, 10.1016/j.neuroscience.2011.01.027 Brosseron, 2021, Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation, J Neurochem, 157, 2210, 10.1111/jnc.15175 Sanfilippo, 2020, Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels, Brain Res, 1749, 147127, 10.1016/j.brainres.2020.147127 Höglund, 2020, Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration, Neurobiol Dis, 134, 104645, 10.1016/j.nbd.2019.104645