Neurofilament light chain predicts disease activity in relapsing-remitting MS

Kristin N. Varhaug1,2,3, Christian Barro1,2,3, Kjetil Bjørnevik1,2,3, Kjell–Morten Myhr1,2,3, Øivind Torkildsen1,2,3, Stig Wergeland1,2,3, Laurence A. Bindoff1,2,3, Jens Kühle1,2,3, Christian A. Vedeler1,2,3
1Department of Global Public Health and Primary Care (K.B.), University of Bergen, Norway
2From the Department of Neurology (K.N.V., K.B., K.-M.M., Ø.T., S.W., L.A.B., C.V.), Haukeland University Hospital; Department of Clinical Medicine (K.N.V., K.-M.M., Ø.T., S.W., L.A.B., C.V.), University of Bergen, Norway; Neurologic Clinic and Policlinic (C.B., J.K.), Departments of Medicine, Clinical Research and Biomedicine, University Hospital Basel, University of Basel, Switzerland; Department of Global Public Health and Primary Care (K.B.), University of Bergen, Norway; and Norwegian MS...
3Norwegian MS-Registry & Biobank (K.-M.M.).

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10.1056/NEJM199801293380502

10.1136/jnnp.64.3.402

10.1016/j.neuron.2016.05.018

10.1002/acn3.325

Steinacker P, Feneberg E, Weishaupt J, et al. Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients. J Neurol Neurosurg Psychiatry 2016;87:12–20.

10.1002/ana.24552

10.1177/1352458516658560

10.1177/1352458515574148

10.1212/WNL.0000000000001491

10.1177/1352458516639384

10.1002/ana.22247

10.1177/1352458515623365

Disanto G, Adiutori R, Dobson R, et al. Serum neurofilament light chain levels are increased in patients with a clinically isolated syndrome. J Neurol Neurosurg Psychiatry 2016;87:126–129.

10.1093/brain/awv017

10.1177/1352458514561906

10.1002/pmic.201500284

10.1093/brain/awq035

10.1001/archneurol.2012.283

10.1089/15368590252917647

10.1002/ana.24954

10.1177/1352458513490544

10.1111/jnc.13881

10.1016/j.jneuroim.2016.12.006

10.1177/1352458511433063

Piehl F Kockum I Khademi M et al. Plasma neurofilament light chain levels in patients with MS switching from injectable therapies to fingolimod. Mult Scler Epub 2017 Jun 1.