Neurobiological model of the persistence of anorexia nervosa

Joanna Steinglass1, B. Timothy Walsh1
11051 Riverside Drive, Unit 98, New York, NY, 10032, USA

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Hudson JI, Hiripi E, Pope Jr HG, Kessler RC. The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol Psychiatry. 2007;61(3):348–58.

Gard MC, Freeman CP. The dismantling of a myth: a review of eating disorders and socioeconomic status. Int J Eat Disord. 1996;20(1):1–12.

APA. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington: American Psychiatric Association Press; 2000.

Herpertz-Dahlmann B. Adolescent eating disorders: update on definitions, symptomatology, epidemiology, and comorbidity. Child Adolesc Psychiatr Clin N Am. 2015;24(1):177–96.

Swanson SA, Crow SJ, Le Grange D, Swendsen J, Merikangas KR. Prevalence and correlates of eating disorders in adolescents. Results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry. 2011;68(7):714–23.

Lock J, Le Grange D, Agras WS, Moye A, Bryson SW, Jo B. Randomized clinical trial comparing family-based treatment with adolescent-focused individual therapy for adolescents with anorexia nervosa. Arch Gen Psychiatry. 2010;67(10):1025–32.

Agras WS, Lock J, Brandt H, Bryson SW, Dodge E, Halmi KA, et al. Comparison of 2 family therapies for adolescent anorexia nervosa: a randomized parallel trial. JAMA Psychiatry. 2014;71(11):1279–86.

Watson HJ, Bulik CM. Update on the treatment of anorexia nervosa: review of clinical trials, practice guidelines and emerging interventions. Psychol Med. 2013;43(12):2477–500.

Hay P. A systematic review of evidence for psychological treatments in eating disorders: 2005–2012. Int J Eat Disord. 2013;46(5):462–9.

Eckert ED, Halmi KA, Marchi P, Grove W, Crosby R. Ten-year follow-up of anorexia nervosa: clinical course and outcome. Psychol Med. 1995;25(1):143–56.

Pike KM. Long-term course of anorexia nervosa: response, relapse, remission, and recovery. Clin Psychol Rev. 1998;18(4):447–75.

Arcelus J, Mitchell AJ, Wales J, Nielsen S. Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders: A Meta-analysis of 36 Studies. Arch Gen Psychiatry. 2011;68(7):724–31.

Sullivan PF. Mortality in anorexia nervosa. Am J Psychiatry. 1995;152(7):1073–5.

Schultz W. Predictive reward signal of dopamine neurons. J Neurophysiol. 1998;80(1):1–27.

Hassani OK, Cromwell HC, Schultz W. Influence of expectation of different rewards on behavior-related neuronal activity in the striatum. J Neurophysiol. 2001;85(6):2477–89.

Dagher A. Functional brain imaging of appetite. Trends Endocrinol Metab. 2012;23(5):250–60.

LaBar KS, Gitelman DR, Parrish TB, Kim YH, Nobre AC, Mesulam MM. Hunger selectively modulates corticolimbic activation to food stimuli in humans. Behav Neurosci. 2001;115(2):493–500.

Smeets PA, Charbonnier L, van Meer F, van der Laan LN, Spetter MS. Food-induced brain responses and eating behaviour. Proc Nutr Soc. 2012;1–10.

Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron. 2002;36(2):199–211.

Kissileff HR, Walsh BT, Kral JG, Cassidy SM. Laboratory studies of eating behavior in women with bulimia. Physiol Behav. 1986;38(4):563–70.

Walsh BT, Hadigan CM, Kissileff HR, LaChaussee JL. Bulimia nervosa. A syndrome of feast and famine. In: Anderson GH, Kennedy SH, editors. The biology of feast and famine. Relevance to eating disorders. San Diego: Academic; 1992. p. 1–20.

Heaner MK, Walsh BT. A history of the identification of the characteristic eating disturbances of Bulimia Nervosa, Binge Eating Disorder and Anorexia Nervosa. Appetite. 2013;65:185–8.

Hetherington MM, Rolls BJ. Eating behavior in eating disorders: response to preloads. Physiol Behav. 1991;50(1):101–8.

Hadigan CM, Anderson EJ, Miller KK, Hubbard JL, Herzog DB, Klibanski A, et al. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. Int J Eat Disord. 2000;28(3):284–92.

Sysko R, Walsh BT, Schebendach J, Wilson GT. Eating behavior among women with anorexia nervosa. Am J Clin Nutr. 2005;82(2):296–301.

Hamilton CM, Strader LC, Pratt JG, Maiese D, Hendershot T, Kwok RK, et al. The PhenX Toolkit: get the most from your measures. Am J Epidemiol. 2011;174(3):253–60.

Mayer LE, Schebendach J, Bodell LP, Shingleton RM, Walsh BT. Eating behavior in anorexia nervosa: Before and after treatment. Int J Eat Disord. 2012; 45(2):290–293.

Huse DM, Lucas AR. Dietary patterns in anorexia nervosa. Am J Clin Nutr. 1984;40(2):251–4.

Schebendach JE, Mayer LE, Devlin MJ, Attia E, Contento IR, Wolf RL, et al. Dietary energy density and diet variety as predictors of outcome in anorexia nervosa. Am J Clin Nutr. 2008;87(4):810–6.

Schebendach J, Mayer LE, Devlin MJ, Attia E, Walsh BT. Dietary energy density and diet variety as risk factors for relapse in anorexia nervosa: A replication. Int J Eat Disord. 2012;45(1):79–84.

Jeffery RW, Adlis SA, Forster JL. Prevalence of dieting among working men and women: the healthy worker project. Health Psychol. 1991;10(4):274–81.

Lowe MR, Annunziato RA, Markowitz JT, Didie E, Bellace DL, Riddell L, et al. Multiple types of dieting prospectively predict weight gain during the freshman year of college. Appetite. 2006;47(1):83–90.

French SA, Jeffery RW, Folsom AR, McGovern P, Williamson DF. Weight loss maintenance in young adulthood: prevalence and correlations with health behavior and disease in a population-based sample of women aged 55–69 years. Int J Obes Relat Metab Disord. 1996;20(4):303–10.

Reba-Harrelson L, Von Holle A, Hamer RM, Swann R, Reyes ML, Bulik CM. Patterns and prevalence of disordered eating and weight control behaviors in women ages 25–45. Eat Weight Disord. 2009;14(4):e190–8.

Liebman M, Cameron BA, Carson DK, Brown DM, Meyer SS. Dietary fat reduction behaviors in college students: relationship to dieting status, gender and key psychosocial variables. Appetite. 2001;36(1):51–6.

Shisslak CM, Crago M, Estes LS. The spectrum of eating disturbances. Int J Eat Disord. 1995;18(3):209–19.

Fairburn CG. Cognitive Behavior Therapy and Eating Disorders. New York: Guilford Press; 2008.

Kaye WH, Wierenga CE, Bailer UF, Simmons AN, Bischoff-Grethe A. Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa. Trends Neurosci. 2013;36(2):110–20.

Kaye W. Neurobiology of anorexia and bulimia nervosa. Physiol Behav. 2008;94(1):121–35.

Steinglass JE, Sysko R, Mayer L, Berner LA, Schebendach J, Wang Y, et al. Pre-meal anxiety and food intake in anorexia nervosa. Appetite. 2010;55(2):214–8.

Lavender JM, De Young KP, Wonderlich SA, Crosby RD, Engel SG, Mitchell JE, et al. Daily Patterns of Anxiety in Anorexia Nervosa: Associations With Eating Disorder Behaviors in the Natural Environment. J Abnorm Psychol. 2013;122(3):672–83.

Steinglass JE, Walsh BT, Stern Y. Set shifting deficit in anorexia nervosa. J Int Neuropsychol Soc. 2006;12(3):431–5.

Tchanturia K, Davies H, Roberts M, Harrison A, Nakazato M, Schmidt U, et al. Poor cognitive flexibility in eating disorders: examining the evidence using the Wisconsin Card Sorting Task. PLoS One. 2012;7(1):e28331.

Holliday J, Tchanturia K, Landau S, Collier D, Treasure J. Is impaired set-shifting an endophenotype of anorexia nervosa? Am J Psychiatry. 2005;162(12):2269–75.

Lang K, Stahl D, Espie J, Treasure J, Tchanturia K. Set shifting in children and adolescents with anorexia nervosa: an exploratory systematic review and meta-analysis. Int J Eat Disord. 2014;47(4):394–9.

Shott ME, Filoteo JV, Jappe LM, Pryor T, Maddox WT, Rollin MD, et al. Altered implicit category learning in anorexia nervosa. Neuropsychology. 2012;26(2):191–201.

Oberndorfer TA, Frank GK, Simmons AN, Wagner A, McCurdy D, Fudge JL, et al. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am J Psychiatry. 2013;170(10):1143–51.

Titova OE, Hjorth OC, Schioth HB, Brooks SJ. Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies. BMC Psychiatry. 2013;13:110.

Frank GK, Shott ME, Hagman JO, Mittal VA. Alterations in Brain Structures Related to Taste Reward Circuitry in Ill and Recovered Anorexia Nervosa and in Bulimia Nervosa. Am J Psychiatry. 2013; 170(10):1152–60.

Wagner A, Aizenstein H, Venkatraman VK, Fudge J, May JC, Mazurkewicz L, et al. Altered reward processing in women recovered from anorexia nervosa. Am J Psychiatry. 2007;164(12):1842–9.

Decker JH, Figner B, Steinglass JE. On Weight and Waiting: Delay Discounting in Anorexia Nervosa Pretreatment and Posttreatment. Biol Psychiatry. 2015;78(9):606–14.

Frank GK, Reynolds JR, Shott ME, Jappe L, Yang TT, Tregellas JR, et al. Anorexia nervosa and obesity are associated with opposite brain reward response. Neuropsychopharmacology. 2012;37(9):2031–46.

Cowdrey FA, Park RJ, Harmer CJ, McCabe C. Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa. Biol Psychiatry. 2011;70(8):736–43.

Fladung AK, Gron G, Grammer K, Herrnberger B, Schilly E, Grasteit S, et al. A neural signature of anorexia nervosa in the ventral striatal reward system. Am J Psychiatry. 2010;167(2):206–12.

Frank GK, Bailer UF, Henry SE, Drevets W, Meltzer CC, Price JC, et al. Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [< sup > 11</sup > C] raclopride. Biol Psychiatry. 2005;58(11):908–12.

Broft A, Slifstein M, Osborne J, Kothari P, Morim S, Shingleton R, et al. Striatal dopamine type 2 receptor availability in anorexia nervosa. Psychiatry Res. 2015;233(3):380–7.

Cha J, Ide JS, Siciliano F, Biezonski D, Bowman D, Simpson HB et al. Hyperconnectivity of reward circuitry in Anorexia Nervosa: A longitudinal, multimodal MRI study. Human brain mapping. revise and resubmit.

Carroll ME, France CP, Meisch RA. Intravenous self-administration of etonitazene, cocaine and phencyclidine in rats during food deprivation and satiation. J Pharmacol Exp Ther. 1981;217(2):241–7.

Cadoni C, Solinas M, Valentini V, Di Chiara G. Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine. Eur J Neurosci. 2003;18(8):2326–34.

Carroll ME, Meisch RA. Oral phencyclidine (PCP) self-administration in rhesus monkeys: effects of feeding conditions. J Pharmacol Exp Ther. 1980;214(2):339–46.

Galvan A, Hare TA, Parra CE, Penn J, Voss H, Glover G, et al. Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J Neurosci. 2006;26(25):6885–92.

Somerville LH, Hare T, Casey BJ. Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescents. J Cogn Neurosci. 2011;23(9):2123–34.

Kaye WH, Fudge JL, Paulus M. New insights into symptoms and neurocircuit function of anorexia nervosa. Nat Rev Neurosci. 2009;10(8):573–84.

Keating C, Tilbrook AJ, Rossell SL, Enticott PG, Fitzgerald PB. Reward processing in anorexia nervosa. Neuropsychologia. 2012;50(5):567–75.

O’Hara CB, Campbell IC, Schmidt U. A reward-centred model of anorexia nervosa: A focussed narrative review of the neurological and psychophysiological literature. Neurosci Biobehav Rev. 2015;52:131–52.

Park RJ, Godier LR, Cowdrey FA. Hungry for reward: How can neuroscience inform the development of treatment for Anorexia Nervosa? Behav Res Ther. 2014;62:47–59.

Fladung AK, Schulze UM, Scholl F, Bauer K, Gron G. Role of the ventral striatum in developing anorexia nervosa. Transl Psychiatry. 2013;3:e315.

Graybiel AM. Habits, rituals, and the evaluative brain. Annu Rev Neurosci. 2008;31:359–87.

Balleine BW, O’Doherty JP. Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action. Neuropsychopharmacology. 2010;35(1):48–69.

O’Doherty J, Dayan P, Schultz J, Deichmann R, Friston K, Dolan RJ. Dissociable roles of ventral and dorsal striatum in instrumental conditioning. Science. 2004;304(5669):452–4.

Daw ND, Shohamy D. The cognitive neuroscience of motivation and learning. Soc Cogn. 2008;26(5):593–620.

Robbins TW, Gillan CM, Smith DG, de Wit S, Ersche KD. Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry. Trends Cogn Sci. 2012;16(1):81–91.

Herholz K, Kreig JC, Emrich HM, Pawlik G, Beil C, Pirke KM, et al. Regional cerebral glucose metabolism in anorexia nervosa measured by positron emission tomography. Biol Psychiatry. 1987;22:43–51.

Delvenne V, Goldman S, De Maertelaer V, Simon Y, Luxen A, Lotstra F. Brain hypometabolism of glucose in anorexia nervosa: normalization after weight gain. Biol Psychiatry. 1996;40:761–8.

Delvenne V, Goldman S, De Maertelaer V, Lotstra F. Brain glucose metabolism in eating disorders assessed by positron emission tomography. Int J Eat Disord. 1999;25(1):29–37.

Krieg JC, Holthoff V, Schreiber W, Pirke KM, Herholz K. Glucose metabolism in the caudate nuclei of patients with eating disorders, measured by PET. Eur Arch Psychiatry Clin Neurosci. 1991;240(6):331–3.

Sanders N, Smeets PA, van Elburg AA, Danner UN, van Meer F, Hoek HW, et al. Altered food-cue processing in chronically ill and recovered women with anorexia nervosa. Front Behav Neurosci. 2015;9:46.

Walsh BT. The enigmatic persistence of anorexia nervosa. Am J Psychiatry. 2013;170(5):477–84.

Steinglass J, Walsh BT. Habit learning and anorexia nervosa: a cognitive neuroscience hypothesis. Int J Eat Disord. 2006;39(4):267–75.

Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Williams LM. Anorexia nervosa: towards an integrative neuroscience model. Eur Eat Disord Rev. 2010;18(3):165–79.

Godier LR, Park RJ. Compulsivity in anorexia nervosa: a transdiagnostic concept. Front Psychol. 2014;5:778.

Marsh R, Maia TV, Peterson BS. Functional disturbances within frontostriatal circuits across multiple childhood psychopathologies. Am J Psychiatry. 2009;166(6):664–74.

Foerde K, Steinglass JE, Shohamy D, Walsh BT. Neural mechanisms supporting maladaptive food choices in anorexia nervosa. Nat Neurosci. 2015;18(11):1571–3.

Steinglass J, Foerde K, Kostro K, Shohamy D, Walsh BT. Restrictive food intake as a choice-A paradigm for study. Int J Eat Disord. 2015;48(1):59–66.

Hare TA, Camerer CF, Rangel A. Self-control in decision-making involves modulation of the vmPFC valuation system. Science. 2009;324(5927):646–8.