Neuro‐ophthalmological findings in sarcoidosis

Wiley - Tập 82 Số 6 - Trang 723-729 - 2004
Kjell Heuser1, Emı́lia Kerty1
1Department of Neurology, Rikshospitalet, University of Oslo, Oslo, Norway

Tóm tắt

Abstract.Purpose:  This review emphasizes the importance of neuro‐ophthalmological signs and symptoms in sarcoidosis. The presence of ophthalmological and neuro‐ophthalmological findings may lead to diagnosis of the disease and the initiation of adequate treatment. Material and Methods:  Patients who had been diagnosed with neurosarcoidosis during the period 1990 − 2001 were identified from the departmental diagnostic index. The history, clinical, laboratory and imaging data of patients were analysed. Results:  Fifteen patients were identified, four men and 11 women, with a mean age of 44.1 years (range 26–65 years). In six of the 15 (40%), neurological deficits were the initial symptoms. Nine (60%) had known sarcoidosis at the time of presentation. Ten patients (66%) had ophthalmological/neuro‐ophthalmological symptoms and signs. Conclusion:  Neuro‐ophthalmological symptoms may develop early in neurosarcoidosis. If neuro‐ophthalmological symptoms arise in patients with established biopsy‐proven sarcoidosis, the diagnosis is usually easy to make. However, a number of patients with neurosarcoidosis may present with neuro‐ophthalmic symptoms before systemic involvement becomes obvious. In this situation the diagnosis is challenging, and the major goal is to establish the presence of systemic sarcoidosis.

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Wiley

Tập 82 Số 6

723-729

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