Neural Processing During Fear Extinction Predicts Intrusive Memories

Stephan F. Miedl1, Julina A. Rattel1, Laila K. Franke1, Jens Blechert1,2, Martin Kronbichler2,3, Victor I. Spoormaker4, Frank H. Wilhelm1
1Clinical Stress and Emotion Laboratory, Division of Clinical Psychology, Psychotherapy, and Health Psychology, Department of Psychology, University of Salzburg, Salzburg, Austria
2Centre for Cognitive Neuroscience, University of Salzburg, Salzburg, Austria
3Neuroscience Institute, Christian Doppler Clinic, Paracelsus Medical University Salzburg, Salzburg, Austria
4Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany

Tài liệu tham khảo

Kilpatrick, 2013, National estimates of exposure to traumatic events and PTSD prevalence using DSM-IV and DSM-5 criteria, J Trauma Stress, 26, 537, 10.1002/jts.21848 2013 Bonanno, 2013, Annual research review: Positive adjustment to adversity-trajectories of minimal-impact resilience and emergent resilience, J Child Psychol Psychiatry, 54, 378, 10.1111/jcpp.12021 Norris, 1992, Epidemiology of trauma: Frequency and impact of different potentially traumatic events on different demographic groups, J Consult Clin Psychol, 60, 409, 10.1037/0022-006X.60.3.409 Ehlers, 2000, A cognitive model of posttraumatic stress disorder, Behav Res Ther, 38, 319, 10.1016/S0005-7967(99)00123-0 Ross, 2017, An integrated neuroscience perspective on formulation and treatment planning for posttraumatic stress disorder: An educational review, JAMA Psychiatry, 74, 407, 10.1001/jamapsychiatry.2016.3325 Orr, 2000, De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder, J Abnorm Psychol, 109, 290, 10.1037/0021-843X.109.2.290 Pittig, 2018, The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research, Neurosci Biobehav Rev, 88, 117, 10.1016/j.neubiorev.2018.03.015 Blechert, 2007, Fear conditioning in posttraumatic stress disorder: Evidence for delayed extinction of autonomic, experiential, and behavioural responses, Behav Res Ther, 45, 2019, 10.1016/j.brat.2007.02.012 Rothbaum, 2003, Applying learning principles to the treatment of post-trauma reactions, Ann N Y Acad Sci, 1008, 112, 10.1196/annals.1301.012 Graham, 2011, The study of fear extinction: Implications for anxiety disorders, Am J Psychiatry, 168, 1255, 10.1176/appi.ajp.2011.11040557 Duits, 2015, Updated meta-analysis of classical fear conditioning in the anxiety disorders, Depress Anxiety, 32, 239, 10.1002/da.22353 Lommen, 2013, Pre-trauma individual differences in extinction learning predict posttraumatic stress, Behav Res Ther, 51, 63, 10.1016/j.brat.2012.11.004 Holmes, 2008, Inducing and modulating intrusive emotional memories: A review of the trauma film paradigm, Acta Psychol, 127, 553, 10.1016/j.actpsy.2007.11.002 Lissek, 2005, Classical fear conditioning in the anxiety disorders: A meta-analysis, Behav Res Ther, 43, 1391, 10.1016/j.brat.2004.10.007 Wegerer, 2013, Relationship between fear conditionability and aversive memories: Evidence from a novel conditioned-intrusion paradigm, PLoS One, 8, 10.1371/journal.pone.0079025 Wegerer, 2013, Emotional learning: A naturalistic experimental paradigm for investigating fear acquisition and extinction using aversive films, Z Psychiatr Psychol Psychother, 61, 93 Wegerer, 2014, Low levels of estradiol are associated with elevated conditioned responding during fear extinction and with intrusive memories in daily life, Neurobiol Learn Mem, 116, 145, 10.1016/j.nlm.2014.10.001 Rattel, 2019, Peritraumatic unconditioned and conditioned responding explains sex differences in intrusions after analogue trauma, Behav Res Ther, 116, 19, 10.1016/j.brat.2019.01.009 Brewin, 2010, Intrusive images in psychological disorders: Characteristics, neural mechanisms, and treatment implications, Psychol Rev, 117, 210, 10.1037/a0018113 Patel, 2012, Neurocircuitry models of posttraumatic stress disorder and beyond: A meta-analysis of functional neuroimaging studies, Neurosci Biobehav Rev, 36, 2130, 10.1016/j.neubiorev.2012.06.003 Pitman, 2012, Biological studies of post-traumatic stress disorder, Nat Rev Neurosci, 13, 769, 10.1038/nrn3339 Rauch, 2006, Neurocircuitry models of posttraumatic stress disorder and extinction: Human neuroimaging research—Past, present, and future, Biol Psychiatry, 60, 376, 10.1016/j.biopsych.2006.06.004 Stark, 2015, Post-traumatic stress influences the brain even in the absence of symptoms: A systematic, quantitative meta-analysis of neuroimaging studies, Neurosci Biobehav Rev, 56, 207, 10.1016/j.neubiorev.2015.07.007 Battaglini, 2016, Intrusive memories of distressing information: An fMRI study, PLoS One, 11, 10.1371/journal.pone.0140871 Bourne, 2013, The neural basis of flashback formation: The impact of viewing trauma, Psychol Med, 43, 1521, 10.1017/S0033291712002358 Clark, 2016, Intrusive memories to traumatic footage: The neural basis of their encoding and involuntary recall, Psychol Med, 46, 505, 10.1017/S0033291715002007 Suarez-Jimenez, 2019, Neural signatures of conditioning, extinction learning, and extinction recall in posttraumatic stress disorder: A meta-analysis of functional magnetic resonance imaging studies [published online ahead of print Jul 1], Psychol Med Fullana, 2016, Neural signatures of human fear conditioning: An updated and extended meta-analysis of fMRI studies, Mol Psychiatry, 21, 500, 10.1038/mp.2015.88 Fullana, 2018, Fear extinction in the human brain: A meta-analysis of fMRI studies in healthy participants, Neurosci Biobehav Rev, 88, 16, 10.1016/j.neubiorev.2018.03.002 Downar, 2016, The neural crossroads of psychiatric illness: An emerging target for brain stimulation, Trends Cogn Sci, 20, 107, 10.1016/j.tics.2015.10.007 Buysse, 1989, The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research, Psychiatry Res, 28, 193, 10.1016/0165-1781(89)90047-4 Laux, 1981 Hautzinger, 1993 Langner, 2010, Presentation and validation of the Radboud Faces Database, Cogn Emot, 24, 1377, 10.1080/02699930903485076 Cascio, 2015, Narcissists’ social pain seen only in the brain, Soc Cogn Affect Neurosci, 10, 335, 10.1093/scan/nsu072 Shirer, 2012, Decoding subject-driven cognitive states with whole-brain connectivity patterns, Cereb Cortex, 22, 158, 10.1093/cercor/bhr099 Miedl, 2016, Criticism hurts everybody, praise only some: Common and specific neural responses to approving and disapproving social-evaluative videos, NeuroImage, 132, 138, 10.1016/j.neuroimage.2016.02.027 Gu, 2013, Anterior insular cortex and emotional awareness, J Comp Neurol, 521, 3371, 10.1002/cne.23368 Phelps, 2005, Contributions of the amygdala to emotion processing: From animal models to human behavior, Neuron, 48, 175, 10.1016/j.neuron.2005.09.025 Pessoa, 2010, Emotion processing and the amygdala: From a “low road” to “many roads” of evaluating biological significance, Nat Rev Neurosci, 11, 773, 10.1038/nrn2920 Miedl, 2018, Neural activity during traumatic film viewing is linked to endogenous estradiol and hormonal contraception, Psychoneuroendocrinology, 87, 20, 10.1016/j.psyneuen.2017.10.006 LaBar, 1998, Human amygdala activation during conditioned fear acquisition and extinction: A mixed-trial fMRI study, Neuron, 20, 937, 10.1016/S0896-6273(00)80475-4 Sander, 2003, The human amygdala: An evolved system for relevance detection, Rev Neurosci, 14, 303, 10.1515/REVNEURO.2003.14.4.303 Norrholm, 2011, Fear extinction in traumatized civilians with posttraumatic stress disorder: Relation to symptom severity, Biol Psychiatry, 69, 556, 10.1016/j.biopsych.2010.09.013 Wiech, 2010, Anterior insula integrates information about salience into perceptual decisions about pain, J Neurosci, 30, 16324, 10.1523/JNEUROSCI.2087-10.2010 Singer, 2004, Empathy for pain involves the affective but not sensory components of pain, Science, 303, 1157, 10.1126/science.1093535 Paulus, 2006, An insular view of anxiety, Biol Psychiatry, 60, 383, 10.1016/j.biopsych.2006.03.042 Seeley, 2007, Dissociable intrinsic connectivity networks for salience processing and executive control, J Neurosci, 27, 2349, 10.1523/JNEUROSCI.5587-06.2007 Lovero, 2009, Anterior insular cortex anticipates impending stimulus significance, NeuroImage, 45, 976, 10.1016/j.neuroimage.2008.12.070 Shin, 2004, Hippocampal function in posttraumatic stress disorder, Hippocampus, 14, 292, 10.1002/hipo.10183 Werner, 2009, Hippocampal function during associative learning in patients with posttraumatic stress disorder, J Psychiatr Res, 43, 309, 10.1016/j.jpsychires.2008.03.011 Bryant, 2005, Neural networks of information processing in posttraumatic stress disorder: A functional magnetic resonance imaging study, Biol Psychiatry, 58, 111, 10.1016/j.biopsych.2005.03.021 Felmingham, 2009, Anterior cingulate activity to salient stimuli is modulated by autonomic arousal in posttraumatic stress disorder, Psychiatry Res, 173, 59, 10.1016/j.pscychresns.2008.12.005 Bishop, 2004, Prefrontal cortical function and anxiety: Controlling attention to threat-related stimuli, Nat Neurosci, 7, 184, 10.1038/nn1173 Whalen, 1998, The emotional counting Stroop paradigm: A functional magnetic resonance imaging probe of the anterior cingulate affective division, Biol Psychiatry, 44, 1219, 10.1016/S0006-3223(98)00251-0 Etkin, 2007, Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia, Am J Psychiatry, 164, 1476, 10.1176/appi.ajp.2007.07030504 Etkin, 2011, Emotional processing in anterior cingulate and medial prefrontal cortex, Trends Cogn Sci, 15, 85, 10.1016/j.tics.2010.11.004 Lopresto, 2016, Neural circuits and mechanisms involved in fear generalization: Implications for the pathophysiology and treatment of posttraumatic stress disorder, Neurosci Biobehav Rev, 60, 31, 10.1016/j.neubiorev.2015.10.009 Onat, 2015, The neuronal basis of fear generalization in humans, Nat Neurosci, 18, 1811, 10.1038/nn.4166 Wilhelm, 2017, Attend or defend? Sex differences in behavioral, autonomic, and respiratory response patterns to emotion-eliciting films, Biol Psychol, 130, 30, 10.1016/j.biopsycho.2017.10.006