Network pharmacology-based study of the protective mechanism of conciliatory anti-allergic decoction on asthma

Ahmed, 2017, The epidemiology of noncommunicable respiratory disease in sub-Saharan Africa, the Middle East, and North Africa, Malawi Med, 29, 203, 10.4314/mmj.v29i2.24 Amato, 2013, Climate change, air pollution and extreme events leading to increasing prevalence of allergic respiratory diseases, Multidiscip Respir Med, 8, 12, 10.1186/2049-6958-8-12 Pond, 2012, Rising to the GINA Asthma Challenge: thinking beyond just asthma, Eur. Respir. J., 40, 280, 10.1183/09031936.00036712 Pinja, 2015, Phenotypes, risk factors, and mechanisms of adult-onset asthma, Mediators Inflamm., 2015, 1 Tan, 2016, Novel biologicals for the treatment of allergic diseases and asthma, Curr. Allergy Asthma Rep., 16, 70, 10.1007/s11882-016-0650-5 Quirce, 2012, Emerging drugs for asthma, Expert Opin Emerg Drugs, 17, 219, 10.1517/14728214.2012.683410 Kruse, 2018, Drug repurposing to treat asthma and allergic disorders: progress and prospects, Allergy, 73, 313, 10.1111/all.13305 Zheng, 2019, Effect of roflumilast and zileuton on the contraction of airway smooth muscle of asthmatic rat, Chin J Mod Appl Pharm, 36, 269 Li, 2007, Traditional Chinese herbal remedies for asthma and food allergy, J. Allergy Clin. Immunol., 120, 25, 10.1016/j.jaci.2007.04.030 Kaixian, 2017, Precision medicine and innovative development of traditional Chinese medicine (TCM), modernization of Traditional Chinese Medicine and Materia Medica, World Sci Technol, 19, 7 Li, 2012, Effect of Chinese medication on the immune function and chronic airway inflammation in asthma children at chronic duration stage, J Trad Chin Med, 53, 2011 Song, 2018, Uncovering the mechanism of Maxing Ganshi Decoction on asthma from a systematic perspective: a network pharmacology study, Sci Rep, 8, 17362, 10.1038/s41598-018-35791-9 Liu, 2013, Effects of taraxasterol on ovalbumin-induced allergic asthma in mice, J. Ethnopharmacol., 148, 787, 10.1016/j.jep.2013.05.006 Yang, 2015, Cordycepin alleviates airway hyperreactivity in a murine model of asthma by attenuating the inflammatory process, Int. Immunopharmacol., 26, 401, 10.1016/j.intimp.2015.04.017 Park, 2009, Quercetin regulates Th1/Th2 balance in a murine model of asthma, Int. Immunopharmacol., 9, 261, 10.1016/j.intimp.2008.10.021 Gong, 2012, Kaempferol suppresses eosionphil infiltration and airway inflammation in airway epithelial cells and in mice with allergic asthma, J. Nutr., 142, 47, 10.3945/jn.111.150748 Sun, 2013, Effects of baicalin on airway remodeling in asthmatic mice, Planta Med., 79, 199, 10.1055/s-0032-1328197 Opoku, 2017, Stigmasterol modulates allergic airway inflammation in guinea pig model of ovalbumin-induced asthma, Mediators Inflamm., 1 Ryu, 2015, Wogonin, a plant flavone from Scutellariae radix, attenuated ovalbumin-induced airway inflammation in mouse model of asthma via the suppression of IL-4/STAT6 signaling, J Clin Biochem Nutr, 57, 105, 10.3164/jcbn.15-45 Spiropoulos, 2008, Role and pharmacogenomics of TNF-alpha in asthma, Mini Rev. Med. Chem., 8, 934, 10.2174/138955708785132828 Berry, 2007, TNF-alpha in asthma, Curr. Opin. Pharmacol., 7, 279, 10.1016/j.coph.2007.03.001 Kobayashi, 2012, IFN-γ elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model, Eur. J. Immunol., 42, 393, 10.1002/eji.201141845 Wegmann, 2009, Th2 cells as targets for therapeutic intervention in allergic bronchial asthma, Expert Rev. Mol. Diagn., 9, 85, 10.1586/14737159.9.1.85 Walsh, 2017, Biologics targeting IL-5, IL-4 or IL-13 for the treatment of asthma – an update, Expert Rev Clin Immunol, 13, 143, 10.1080/1744666X.2016.1216316 Walsh, 2018, Recent developments in the use of biologics targeting IL-5, IL-4 or IL-13 in severe refractory asthma, Expert Rev Respir Med, 2, 957, 10.1080/17476348.2018.1520095 Wang, 2019, Establishment of a high-throughput drug screening cell inflammatory model based on NF-κB signaling pathway, Chin J Mod Appl Pharm, 36, 397 Zhou, 2018, Alleviating airway inflammation by inhibiting ERK-NF-κB signaling pathway by blocking Kv1.3 channels, PLoS ONE, 13, e0199167 Zhang, 2017, Deguelin attenuates allergic airway inflammation via inhibition of NF-κb pathway in mice, Int J Biol Sci, 13, 492, 10.7150/ijbs.17238 O’Connell, 2015, IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells, Am J Physiol Lung Cell Mol Physiol, 309, L348, 10.1152/ajplung.00099.2015