Network pharmacology-based analysis of the mechanism of Guben Sanjie Pill in the treatment of lung cancer

Journal of Herbal Medicine - Tập 36 - Trang 100608 - 2022
Kai Wang1, Lu Zhai1, Feng Li1, Yunyun Cao1, Pan Lu1, Xiaoning Liu1, Yarong Liu1, Na Li1, Xinhan Zhao2
1Department of Integrated Traditional Chinese and Western Medicine, Xi'an Changan District Hospital, Xi’an, Shaanxi 710061, China
2Department of Oncology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

Tài liệu tham khảo

Bi, 2017, The component formula of Salvia miltiorrhiza and Panax ginseng induces apoptosis and inhibits cell invasion and migration through targeting PTEN in lung cancer cells, Oncotarget, 8, 101599, 10.18632/oncotarget.21354 Bischoff, 2008, Quercetin: potentials in the prevention and therapy of disease, Curr. Opin. Clin. Nutr. Metab. Care, 11, 733, 10.1097/MCO.0b013e32831394b8 Blanco-Aparicio, 2010, Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models, PLoS One, 5, 10.1371/journal.pone.0009305 Boezio, 2017, Network-based approaches in pharmacology, Mol. Inform., 36, 10.1002/minf.201700048 Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 68, 394, 10.3322/caac.21492 Chang, 2017, Quercetin suppresses the metastatic ability of lung cancer through inhibiting snail-dependent Akt activation and Snail-independent ADAM9 expression pathways, Biochim. Biophys. Acta Mol. Cell Res., 1864, 1746, 10.1016/j.bbamcr.2017.06.017 Chen, 2016, The Hedyotis diffusa Willd. (Rubiaceae): a review on phytochemistry, pharmacology, quality control and pharmacokinetics, Molecules, 21, 10.3390/molecules21060710 Chen, 2016, Drug target identification using network analysis: taking active components in Sini decoction as an example, Sci. Rep., 6, 24245, 10.1038/srep24245 Chen, 2016, Eyes on systems pharmacology, Pharmacol. Res., 114, 39, 10.1016/j.phrs.2016.09.026 Chen, 2016, Total flavonoids of Hedyotis diffusa Willd inhibit inflammatory responses in LPS-activated macrophages via suppression of the NF-κB and MAPK signaling pathways, Exp. Ther. Med., 11, 1116, 10.3892/etm.2015.2963 Dahabreh, 2013, Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer, Am. J. Epidemiol., 177, 1317, 10.1093/aje/kws394 Dai, 2014, In vitro anticancer activity of myricanone in human lung adenocarcinoma A549 cells, Chemotherapy, 60, 81, 10.1159/000371738 Guo, 2021, Quercetin induces pro-apoptotic autophagy via SIRT1/AMPK signaling pathway in human lung cancer cell lines A549 and H1299 in vitro, Thorac. Cancer, 12, 1415, 10.1111/1759-7714.13925 Häggblad Sahlberg, 2017, Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells, Int. J. Oncol., 50, 5, 10.3892/ijo.2016.3771 Hirpara, 2009, Quercetin and its derivatives: synthesis, pharmacological uses with special emphasis on anti-tumor properties and prodrug with enhanced bio-availability, Anti-Cancer Agents Med. Chem., 9, 138, 10.2174/187152009787313855 Hirsch, 2017, Lung cancer: current therapies and new targeted treatments, Lancet, 389, 299, 10.1016/S0140-6736(16)30958-8 Hsu, 2012, Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway, Lung Cancer, 75, 167, 10.1016/j.lungcan.2011.07.001 Huang, 2017, Molecular targets and associated potential pathways of danlu capsules in hyperplasia of mammary glands based on systems pharmacology, Evid. Based Complement. Altern. Med., 2017, 1930598, 10.1155/2017/1930598 Jalal, 2019, Identification and quantification of quercetin, a major constituent of Artocarpus altilis by targeting related genes of apoptosis and cell cycle: in vitro cytotoxic activity against human lung carcinoma cell lines, Nutr. Cancer, 71, 792, 10.1080/01635581.2018.1516790 Jia, 2018, Impact of serum vascular endothelial growth factor and interleukin-6 on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small-cell lung cancer, Lung Cancer, 125, 22, 10.1016/j.lungcan.2018.08.025 Kuo, 2004, Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells, J. Biol. Chem., 279, 55875, 10.1074/jbc.M407985200 Lee, 2015, Quercetin enhances chemosensitivity to gemcitabine in lung cancer cells by inhibiting heat shock protein 70 expression, Clin. Lung Cancer, 16, e235, 10.1016/j.cllc.2015.05.006 Li, 2019, Quercetin is the active component of Yang-Yin-Qing-Fei-Tang to induce apoptosis in non-small cell lung cancer, Am. J. Chin. Med., 47, 879, 10.1142/S0192415X19500460 Li, 2015, Network based approach to drug discovery: a mini review, Mini Rev. Med. Chem., 15, 687, 10.2174/1389557515666150219143933 Liu, 2011, Traditional Chinese medicine in cancer care: a review of case reports published in Chinese literature, Forsch. Komplement., 18, 257, 10.1159/000333065 Liu, 2020, IL-6 promotes metastasis of non-small-cell lung cancer by up-regulating TIM-4 via NF-κB, Cell Prolif., 53, 10.1111/cpr.12776 Lv, 2018, Polymorphism in lncRNA AC008392.1 and its interaction with smoking on the risk of lung cancer in a Chinese population, Cancer Manag. Res., 10 Ma, 2016, Prognostic and predictive effect of TP53 mutations in patients with non-small cell lung cancer from adjuvant cisplatin-based therapy randomized trials: a LACE-bio pooled analysis, J. Thorac. Oncol. Off. Publ. Int. Assoc. Study Lung Cancer, 11, 850 Ma, 2015, Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro, J. Ethnopharmacol., 173, 91, 10.1016/j.jep.2015.07.016 Mihara, 2012, IL-6/IL-6 receptor system and its role in physiological and pathological conditions, Clin. Sci., 143, 10.1042/CS20110340 Peng, 2018, Alleviating the intestinal absorption of rhein in rhubarb through herb compatibility in Tiaowei Chengqi Tang in Caco-2 cells, Evid. Based Complement. Altern. Med., 2018, 7835128, 10.1155/2018/7835128 Qiao, 2013, The association between TP53 Arg72Pro polymorphism and lung cancer susceptibility: evidence from 30,038 subjects, Lung, 191, 369, 10.1007/s00408-013-9461-9 Ru, 2014, TCMSP: a database of systems pharmacology for drug discovery from herbal medicines, J. Cheminform., 6, 13, 10.1186/1758-2946-6-13 Shafabakhsh, 2019, Quercetin: a natural compound for ovarian cancer treatment, J. Ovarian Res., 12, 55, 10.1186/s13048-019-0530-4 Siegel, 2019, Cancer statistics, 2019, CA Cancer J. Clin., 69, 7, 10.3322/caac.21551 Tang, 2019, SIX4 acts as a master regulator of oncogenes that promotes tumorigenesis in non-small-cell lung cancer cells, Biochem. Biophys. Res. Commun., 516, 851, 10.1016/j.bbrc.2019.06.114 Tao, 2013, Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease, J. Ethnopharmacol., 145, 1, 10.1016/j.jep.2012.09.051 Tao, 2013, Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease, J. Ethnopharmacol., 145, 1, 10.1016/j.jep.2012.09.051 Trott, 2010, AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading, J. Comput. Chem., 31, 455, 10.1002/jcc.21334 Wang, 2017, Effects of javanica oil emulsion injection combined with radiotherapy versus radiotherapy alone on the efficacy and safety in patients with esophageal cancer: a pooled analysis of 1269 cases, J. BUON Off. J. Balk. Union Oncol., 22, 985 Wang, 2014, Which is the best Chinese herb injection based on the FOLFOX regimen for gastric cancer? A network meta- analysis of randomized controlled trials, Asian Pac. J. Cancer Prev. APJCP, 15, 4795, 10.7314/APJCP.2014.15.12.4795 Wang, 2016, Berberine suppresses cyclin D1 expression through proteasomal degradation in human hepatoma cells, Int. J. Mol. Sci., 17, 10.3390/ijms17111899 Wang, 2018, Network pharmacology-based validation of caveolin-1 as a key mediator of Ai Du Qing inhibition of drug resistance in breast cancer, Front. Pharmacol., 9, 1106, 10.3389/fphar.2018.01106 Wu, 2018, miR-377-5p inhibits lung cancer cell proliferation, invasion, and cell cycle progression by targeting AKT1 signaling, J. Cell. Biochem. Wu, 2018, Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer, Cancer Med., 7, 1546, 10.1002/cam4.1419 Xu, 2020, A TP53-associated gene signature for prediction of prognosis and therapeutic responses in lung squamous cell carcinoma, Oncoimmunology, 9, 1731943, 10.1080/2162402X.2020.1731943 Xu, 2014, The possibility of traditional chinese medicine as maintenance therapy for advanced nonsmall cell lung cancer, Evid. Based Complement. Altern. Med. eCAM, 2014, 10.1155/2014/278917 Xu, 2012, A novel chemometric method for the prediction of human oral bioavailability, Int. J. Mol. Sci., 13, 6964, 10.3390/ijms13066964 Xue, 2013, TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis, Nucleic Acids Res., 41 (Database Issue), D1089 Yao, 2013, Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction, J. Ethnopharmacol., 150, 619, 10.1016/j.jep.2013.09.018 Ye, 2011, HIT: linking herbal active ingredients to targets, Nucleic Acids Res., 39 (Database Issue), D1055, 10.1093/nar/gkq1165 Ye, 2016, Drug repositioning through network pharmacology, Curr. Top. Med. Chem., 16, 3646, 10.2174/1568026616666160530181328 Yoo, 2014, The novel miR-9500 regulates the proliferation and migration of human lung cancer cells by targeting Akt1, Cell Death Differ., 21, 1150, 10.1038/cdd.2014.33 Zhang, 2018, LncRNA PICART1 suppressed non-small cell lung cancer cells proliferation and invasion by targeting AKT1 signaling pathway, Am. J. Transl. Res., 10, 4193 Zhang, 2016, Polypharmacology in drug discovery: a review from systems pharmacology perspective, Curr. Pharm. Des., 22, 3171, 10.2174/1381612822666160224142812 Zhang, 2012, Drug repositioning: an important application of network pharmacology, Chin. J. Pharmacol. Toxicol., 26, 779 Zhao, 2020, TP53 somatic mutations are associated with poor survival in non-small cell lung cancer patients who undergo immunotherapy, Aging, 12, 14556, 10.18632/aging.103502 Zheng, 2019, An autocrine IL-6/IGF-1R loop mediates EMT and promotes tumor growth in non-small cell lung cancer, Int. J. Biol. Sci., 15, 1882, 10.7150/ijbs.31999